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Description References
Fenamiphos structure
Chemical Name:
sra3886;NEMACUR;B 68138;Nenacur;SRA 3886;ent27572;nemacurp;BAY 68138;FenaMifos;ai3-27572
Molecular Formula:
Formula Weight:
MOL File:

Fenamiphos Properties

Melting point:
Flash point:
100 °C
storage temp. 
Water Solubility 
0.07 g/100 mL
Exposure limits
OSHA PEL: TWA 0.1 mg/m3; ACGIH TLV: TWA 0.1 mg/m3.
CAS DataBase Reference
22224-92-6(CAS DataBase Reference)
NIST Chemistry Reference
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T+;N,N,T+
Risk Statements  24-28-50/53-36-26/28
Safety Statements  23-28-36/37-45-60-61-35-26
RIDADR  UN 2811/3017
WGK Germany  3
RTECS  TB3675000
HazardClass  6.1(a)
PackingGroup  I
Hazardous Substances Data 22224-92-6(Hazardous Substances Data)
Toxicity LD50 orally in rats (mg/kg): 10-25 (Waggoner, Khasawinah); LD50 orally in birds (mg/kg): 2.4 (Hill, Camardese)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Fenamiphos price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 45483 Fenamiphos PESTANAL 22224-92-6 250mg $60.2 2018-11-20 Buy

Fenamiphos Chemical Properties,Uses,Production


Fenamiphos is a colourless crystal or a tan, waxy solid. It is non-corrosive to metals and breaks down readily in strong acids and bases. Fenamiphos is used as a nematicide and an insecticide for use on a wide variety of field, vegetable, and fruit crops. Fenamiphos has been used primarily to control nematodes and thrips on various agricultural crops (i.e., citrus, grapes, peanuts, pineapples, tobacco, etc.) and non-agricultural (i.e., turf and ornamentals) sites.Alternatively, it can also be used for the treatment of other kinds of invertebrates such as sucking insects and spider mite. Fenamiphos takes effects through inhibiting the acetylcholinesterase in the pests. There are no residential uses for fenamiphos and is a Restricted Use Pesticide (RUP) due to high acute toxicity and toxicity to wildlife.


Chemical Properties

Fenamiphos is a colorless crystal or a tan, waxy solid. It is non-corrosive to metals and breaks down readily in strong acids and bases. Fenamiphos is used as a nematicide and an insecticide. It is sparingly soluble in water, but readily soluble in dichloromethane, isopropanol, and toluene. It is used primarily for the control of nematodes and thrips on citrus, grapes, peanuts, pineapples, tobacco, turf, and ornamentals. There are no residential uses for fenamiphos. The US EPA has grouped fenamiphos as an RUP owing to its high acute toxicity and toxicity to wildlife. Reports have indicated that the manufacture and sale of fenamiphos is to be phased out by 2007–2008.

Chemical Properties

Yellow Solid


Nematocide and insecticide.




Systemic broad spectrum nematocide with anticholinesterase activity. Nematocide.

General Description

Brown waxy solid or colorless solid. Used as a nematocide.

Air & Water Reactions

Fenamiphos is hydrolyzed by strong acids and strong alkalis.

Reactivity Profile

Organothiophosphates, such as Fenamiphos, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.


Toxic by inhalation and skin contact. Questionable carcinogen.

Health Hazard

Occupational exposures to fenamiphos cause severe toxicity and adverse health effects. It inhibits the activity of the cholinesterase enzyme in humans, leading to over stimulation of the nervous system. The symptoms of poisoning include, but are not restricted to, nausea, dizziness, confusion, impaired memory, disorientation, severe depression, irritability, headache, speech diffi culties, delayed reaction times, nightmares, sleepwalking, and drowsiness or insomnia. Very high exposures, such as accidental ingestion and/or major spillage, cause respiratory paralysis and death. Laboratory studies have indicated that the teratogenic effects of fenamiphos occurred only at levels that caused overt maternal toxicity and are likely indirect consequences of this toxicity. Other studies have indicated that fenamiphos is non-mutagenic and also have no evidence suggesting that fenamiphos is carcinogenic to animals and humans.

Health Hazard

Fenamiphos is highly toxic orally, by inhalation, and by absorption through the skin. (Non-Specific -- Parathion) Death may occur from respiratory failure.

Fire Hazard

(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Emits toxic fumes of nitrogen oxides, phosphorus oxides, and sulfur oxides when heated to decomposition.

Agricultural Uses

Nematicide, Insecticide: A U.S. EPA restricted Use Pesticide (RUP). Fenamiphos is an organophosphate nematicide used to control a wide variety of nematode (roundworm) pests. Nematodes can live as parasites on the outside or the inside of a plant. They may be free living or associated with cyst and root-knot formations in plants. Fenamiphos is used on a variety of plants including tobacco, turf, bananas, pineapples, citrus and other fruit vines, some vegetables, and grains. The compound is absorbed by roots and is then distributed throughout the plant. Fenamiphos, as is typical of other organophosphates, blocks the enzyme acetylcholinesterase in the target pest. The pesticide also has secondary activity against other invertebrates such as sucking insects and spider mites.

Trade name

BAY 68138®; Bayer 68138®; NEMACUR®; NEMACURP®

Safety Profile

Poison by ingestion, inhalation, and skin contact. When heated to decomposition it emits very toxic fumes of NOx, POx, and SOx.

Environmental Fate

Soil. Oxidizes in soil to the corresponding sulfone and sulfoxide (Lee et al., 1986). Fenamiphos rapidly degraded in Arredondo soil to fenamiphos sulfone and at the sametime to the corresponding phenol. The half-life in this soil is 38–67 days (Ou and Rao, 1986).
Surface Water. In estuarine water, the half-life of fenamiphos was 1.80 days (Lacorte et al., 1995).
Chemical/Physical. Emits toxic fumes of phosphorus, nitrogen and sulfur oxides when heated to decomposition (Sax and Lewis, 1987; Lewis, 1990).

Fenamiphos Preparation Products And Raw materials

Raw materials

Preparation Products

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