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KEMPTIDE

KEMPTIDE structure

CAS No.: 65189-71-1

Chemical Name:: KEMPTIDE

Synonyms: LRRASLG;KEMPTIDE;Nsc332190;KEMPTIDE ACETATE;KEMPTIDE [LRRASLG];KEMPTIDE ACETATE SALT;PHOSPHATE ACCEPTOR PEPTIDE;LEU-ARG-ARG-ALA-SER-LEU-GLY;LEU-ARG-ARG-ALA-SER-LEU-GLY-OH;Polypeptide (boehringer) 600925

CBNumber:: CB7234741

Molecular Formula:: C32H61N13O9

Molecular Weight:: 771.91

MDL Number:: MFCD00076710

MOL File:: 65189-71-1.mol

Last updated:2024-03-27 11:49:37

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KEMPTIDE Properties

Density	1.43±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	H₂O: 20 mg/mL
pka	3.32±0.10(Predicted)
form	powder
color	white
Water Solubility	Soluble in water (20 mg/ml).
Sequence	H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
F	3-10
HS Code	35079090

KEMPTIDE price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	J60591	Kemptide	65189-71-1	5mg	$150	2023-06-20	Buy
Alfa Aesar	J60591	Kemptide	65189-71-1	1mg	$44	2021-12-16	Buy
Cayman Chemical	15555	Kemptide ≥95%	65189-71-1	1mg	$44	2024-03-01	Buy
Cayman Chemical	15555	Kemptide ≥95%	65189-71-1	5mg	$140	2024-03-01	Buy
Cayman Chemical	15555	Kemptide ≥95%	65189-71-1	10mg	$257	2024-03-01	Buy

Product number	Packaging	Price	Buy
J60591	5mg	$150	Buy
J60591	1mg	$44	Buy
15555	1mg	$44	Buy
15555	5mg	$140	Buy
15555	10mg	$257	Buy

KEMPTIDE Chemical Properties,Uses,Production

Uses

Kemptide, phosphate acceptor, is shown to be a basic serine-containing heptapeptide corresponding to a sequence from pig liver pyruvate kinase. This synthetic peptide is a substrate of PKA (cyclic AMP-dependent protein kinase) and is phosphorylated and activated after microinjection into Xenopus oocytes. Exposure of Kemptide to insulin has demonstrated an increase in activation of this agent, which can be inhibited by the catalytic subunit of phosphatase 2A.

Biological Activity

kemptide is a synthetic heptapeptide that acts as a substrate for camp-dependent protein kinase (pk) [1].cyclic amp-dependent protein kinase is the sole intracellular acceptor for cyclic amp in all cell types. protein phosphorylation by different types of protein kinase (pk) activities comprises a form of protein modification that plays an important role in the regulation of numerous biological processes [1][2].kemptide is a novel synthetic heptapeptide phosphate acceptor that acts as a substrate for camp-dependent protein kinase. kemptide had all the properties of a cytophilic substrate and could preserving cell membrane intactness when added to cultured cells. in the presence of extracellular atp and camp, different types of intact cells catalyzed the phosphorylation of kemptide with km values of 3-4 μm. kemptide phosphorylation was influenced by pki, the inhibitory protein specific for camp-pk [1]. kemptide was usually used as a substrate for detection of activities of soluble a-kinase isolated from guinea-pig lung parenchyma and from bovine tracheal smooth muscle [2][3].

References

[1]. kübler d, pyerin w, bill o, et al. evidence for ecto-protein kinase activity that phosphorylates kemptide in a cyclic amp-dependent mode. j biol chem. 1989 aug 25;264(24):14549-55.
[2]. giembycz ma, diamond j. evaluation of kemptide, a synthetic serine-containing heptapeptide, as a phosphate acceptor for the estimation of cyclic amp-dependent protein kinase activity in respiratory tissues. biochem pharmacol. 1990 jan 15;39(2):271-83.
[3]. langlands jm, rodger iw. determination of soluble camp-dependent protein kinase activity in guinea-pig tracheal smooth muscle. preferential use of kemptide as a phosphorylating substrate. biochem pharmacol. 1990 apr 15;39(8):1365-74.

KEMPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

KEMPTIDE Suppliers

Global( 100)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
Nanjing TGpeptide	+86-13347807150 +86-13347807150	support@tgpeptide.com	China	3279	58

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Cellmano Biotech Limited	58
career henan chemical co	58
BOC Sciences	58
Zhejiang J&C Biological Technology Co.,Limited	58
Hangzhou Go Top Peptide Biotech	58
Chengdu Youngshe Chemical Co., Ltd.	58
LEAP CHEM CO., LTD.	58
Hebei Miaoyin Technology Co.,Ltd	58
Nanjing TGpeptide	58

View Lastest Price from KEMPTIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-19	KEMPTIDE 65189-71-1	US $7.00 / KG	1KG	99%	100kg	Career Henan Chemical Co

KEMPTIDE
65189-71-1
US $7.00 / KG
99%
Career Henan Chemical Co

65189-71-1(KEMPTIDE)Related Search:

KEMPTIDE, SYNTHETIC, >97% PURITY KEMPTIDE [LRRWSLG], [TRP4],[TRP4]-KEMPTIDE KEMPTIDE KEMPTIDE [LRRASLG], BIOTINYLATED-LC KEMPTIDE, 5-FAM LABELED,KEMPTIDE [LRRASLG], 5-FAM LABELED

KEMPTIDE, 5-TMR LABELED,KEMPTIDE [LRRASLG], 5-TMR LABELED [PSER5]-KEMPTIDE, BIOTINYLATED-LC [PSER5]-KEMPTIDE, 5-TMR LABELED CYS-KEMPTIDE KEMPTIDE [LRRASLG], BIOTINYLATED

[PSER5]-KEMPTIDE, BIOTINYLATED [PSER5]-KEMPTIDE KEMPTIDE [LRRAALG], NEGATIVE CONTROL KEMPTIDE, AMIDE Kemptide [LRRASLG], Hilytefluor488 labeled

Kemptide (Phosphate Acceptor Peptide) KEMPTIDE [LRRASVA], [VAL6, ALA7],(VAL6,ALA7)-KEMPTIDE KEMPTIDE [LKRA-PT-LG], [LYS2, PT5]

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L-Leucyl-L-arginyl-L-arginyl-L-alanyl-L-seryl-L-leucylglycine Glycine,L-leucyl-L-arginyl-L-arginyl-L-alanyl-L-seryl-L-leucyl- LRRASLG LEU-ARG-ARG-ALA-SER-LEU-GLY LEU-ARG-ARG-ALA-SER-LEU-GLY-OH KEMPTIDE [LRRASLG] KEMPTIDE ACETATE SALT KEMPTIDE H-LEU-ARG-ARG-ALA-SER-LEU-GLY-OH ARG-ARG-LYS-ALA-SER-GLY-PRO-PRO-VAL PHOSPHATE ACCEPTOR PEPTIDE PHOSPHATE ACCEPTOR PEPTIDE ACETATE SALT KEMPTIDE ACETATE H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val-OH Nsc332190 Polypeptide (boehringer) 600925 Kemptide acetate salt, ≥95% (HPLC) 65189-71-1 Cell Biology Cell Signaling and Neuroscience BioChemical Kinase/Phosphatase Biology Protein Kinase A (PKA) Serine/Threonine Kinase Substrates Peptide