4-Hydroxy Cholesterol-d7
- CAS No.
- 1246302-80-6
- Chemical Name:
- 4-Hydroxy Cholesterol-d7
- Synonyms
- 4-Hydroxy Cholesterol-d7;4β-Hydroxy Cholesterol-d7;cholest-5-ene-3,4-diol-d7;4-beta-Hydroxy Cholesterol-d7;CHOLEST-5-ENE-3,4-DIOL-D7;4-HYDROXYCHOLESTEROL-D7;(3S,4R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6,7,7,7-tetradeuterio-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,4-diol
- CBNumber:
- CB72487154
- Molecular Formula:
- C27H46O2
- Molecular Weight:
- 402.65294
- MDL Number:
- MFCD15071187
- MOL File:
- 1246302-80-6.mol
4-Hydroxy Cholesterol-d7 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25971 | 4β-hydroxy Cholesterol-d7 ≥99% deuterated forms (d1-d7) | 1246302-80-6 | 500μg | $189 | 2024-03-01 | Buy |
| Cayman Chemical | 25971 | 4β-hydroxy Cholesterol-d7 ≥99% deuterated forms (d1-d7) | 1246302-80-6 | 1mg | $359 | 2024-03-01 | Buy |
| TRC | H917982 | 4β-HydroxyCholesterol-d7 | 1246302-80-6 | 1mg | $205 | 2021-12-16 | Buy |
| Usbiological | 013561 | 4β-Hydroxy Cholesterol-d7 | 1246302-80-6 | 1mg | $496 | 2021-12-16 | Buy |
| AK Scientific | 0465CK | Cholest-5-en-3beta,4beta-diol(d7) | 1246302-80-6 | 1mg | $498 | 2021-12-16 | Buy |
4-Hydroxy Cholesterol-d7 Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential and also a new endogenous CYP3A marker.
Uses
4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
Uses
4β-hydroxycholesterol-d7 has been used:
- as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysis
- to spike serum samples for mass spectrometry measurements
- as an internal standard for the quantification of human colon biopsies samples using HPLC-MS
General Description
4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.
Biochem/physiol Actions
4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.
4-Hydroxy Cholesterol-d7 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1976 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |