6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
![6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Structure](CAS2/GIF/479347-86-9.gif)
- CAS No.
- 479347-86-9
- Chemical Name:
- 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
- Synonyms
- NSC7169;NSC 7169;NSC-7169;3-dione . 2Na;NBQX (sodium salt);FG 9202 disodium salt;6-Nitro-7-sulphamoylbenzo(f)-quinoxaline-2;6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE-2;3-DIONE . 2NA;FG 9202 DISODIUM SALT;Benzo[f]quinoxaline-7-sulfonamide,1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-,sodium salt(1:2)
- CBNumber:
- CB72511387
- Molecular Formula:
- C24H14N8Na2O12S2
- Molecular Weight:
- 716.5239
- MDL Number:
- MOL File:
- 479347-86-9.mol
| storage temp. | -20°C Freezer |
|---|---|
| solubility | Soluble in H2O |
| form | crystalline solid |
| color | Orange |
| Water Solubility | Soluble to 100 mM in water |
| Stability | Store in Freezer at -20°C |
| FDA UNII | FSU8N86V27 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14914 | NBQX (sodium salt) ≥98% | 479347-86-9 | 10mg | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 14914 | NBQX(sodiumsalt) ≥98% | 479347-86-9 | 100mg | $874 | 2024-03-01 | Buy |
| Cayman Chemical | 14914 | NBQX (sodium salt) ≥98% | 479347-86-9 | 5mg | $65 | 2021-12-16 | Buy |
| Cayman Chemical | 14914 | NBQX (sodium salt) ≥98% | 479347-86-9 | 25mg | $262 | 2024-03-01 | Buy |
| Cayman Chemical | 14914 | NBQX (sodium salt) ≥98% | 479347-86-9 | 50mg | $493 | 2024-03-01 | Buy |
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Chemical Properties,Uses,Production
Chemical Properties
Deep Red-Brown Solid
Uses
A potent and discriminating antagonist for AMPA binding sites.
Biological Activity
nbqx disodium salt is a potent, highly selective and competitive antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (ampa) receptors (ampars). the ampar is one type of ionotropic glutamate receptors, well known to be involved in various neurological disorders such as alzheimer disease, schizophrenia, and epilepsy, by mediating long-term potentiation, excitotoxicity, or both. inhibition of ampars with nbqx shows neuroprotective and anticonvulsant activity.1. fukushima k, tabata y, imaizumi y, et al. characterization of human hippocampal neural stem/progenitor cells and their application to physiologically relevant assays for multiple ionotropic glutamate receptors. journal of biomolecular screening, 2014, 19(8): 1174-1184.2. chen w, li ys, gao j, et al. ampa receptor antagonist nbqx decreased seizures by normalization of perineuronal nets. plos one, 2016, 11(11): e0166672.
storage
-20°C
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Preparation Products And Raw materials
Raw materials
Preparation Products
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| TargetMol Chemicals Inc. | 021-33632979 15002134094 | marketing@targetmol.com | China | 7934 | 58 |