ChemicalBook >> CAS DataBase List >>PS 48

PS 48

PS 48 structure

CAS No.: 1180676-32-7

Chemical Name:: PS 48

Synonyms: PS 48;CS-1466;PS 48;PS-48;PS-48;PS 48;PS48;5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid;(Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid;(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid;2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)-

CBNumber:: CB72518801

Molecular Formula:: C17H15ClO2

Molecular Weight:: 286.75

MDL Number:: MFCD17215962

MOL File:: 1180676-32-7.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:22

Request For Quotation

PS 48 Properties

Melting point	114-115℃
Boiling point	444.1±24.0 °C(Predicted)
Density	1.225±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >20mg/mL
pka	4.55±0.10(Predicted)
form	powder
color	white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3

PS 48 price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P0022	PS48 ≥98% (HPLC)	1180676-32-7	5mg	$80.4	2024-03-01	Buy
Sigma-Aldrich	P0022	PS48 ≥98% (HPLC)	1180676-32-7	25mg	$538	2024-03-01	Buy
TRC	P839688	PS48	1180676-32-7	10mg	$85	2021-12-16	Buy
TRC	P839688	PS48	1180676-32-7	50mg	$280	2021-12-16	Buy
Usbiological	463157	PS 48	1180676-32-7	10mg	$355	2021-12-16	Buy

Product number	Packaging	Price	Buy
P0022	5mg	$80.4	Buy
P0022	25mg	$538	Buy
P839688	10mg	$85	Buy
P839688	50mg	$280	Buy
463157	10mg	$355	Buy

PS 48 Chemical Properties,Uses,Production

Uses

PS 48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator.

Biochem/physiol Actions

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

PS 48 synthesis

Synthesis of PS 48 from 4-Chlorochalcone

PS 48 Preparation Products And Raw materials

Raw materials

3-(4-CHLOROPHENYL)PROPIOPHENONE 4-Chlorochalcone

Preparation Products

PS 48 Suppliers

Global( 89)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Creative Enzymes	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from PS 48 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-23	(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid 1180676-32-7	US $1.00 / g	100g	99%	G/KG/T	Career Henan Chemical Co

(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid
1180676-32-7
US $1.00 / g
99%
Career Henan Chemical Co

(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid PS 48 (Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid PS 48;PS-48 PS-48;PS 48;PS48 CS-1466 2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)- 1180676-32-7