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ChemicalBook >> CAS DataBase List >>(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Structure
(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide structure
CAS No.
330676-02-3
Chemical Name:
(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Synonyms
KH 7;sAC inhibitor KH7;inhibit,KH 7,Adenylate Cyclase,Adenylyl cyclase,KH7,Inhibitor,KH-7;(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide;(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
CBNumber:
CB72518881
Molecular Formula:
C17H15BrN4O2S
Molecular Weight:
419.3
MDL Number:
MFCD01230899
MOL File:
330676-02-3.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Properties

Density 1.61±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form powder
pka 7.90±0.48(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
NFPA 704
0
2 0

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich K3394 KH7 ≥98% (HPLC) 330676-02-3 5mg $112.4 2024-03-01 Buy
Sigma-Aldrich K3394 KH7 ≥98% (HPLC) 330676-02-3 25mg $424 2024-03-01 Buy
Cayman Chemical 13243 KH7 ≥98% 330676-02-3 5mg $81 2024-03-01 Buy
Cayman Chemical 13243 KH7 ≥98% 330676-02-3 10mg $152 2024-03-01 Buy
Cayman Chemical 13243 KH7 ≥98% 330676-02-3 25mg $356 2024-03-01 Buy
Product number Packaging Price Buy
K3394 5mg $112.4 Buy
K3394 25mg $424 Buy
13243 5mg $81 Buy
13243 10mg $152 Buy
13243 25mg $356 Buy

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Chemical Properties,Uses,Production

Uses

KH7 has been used:

  • as a soluble adenyl?cyclase?(sAC) antagonist to study its effect on the signaling pathway mediated by the action of transient? receptor type 1 (TRPV1) in sperm cells.
  • as a selective sAC antagonist to study its effect on the signaling pathway of proton gated channels (HV1) induced action in sperm cells.
  • as a sAC inhibitor to study its effects on cAMP increase in monophosphorylated myosin light chain (pMLC).

Biochem/physiol Actions

KH7 is a selective inhibitor of soluble adenylyl cyclase. Soluble adenylyl cyclase (sAC) is an ubiquitously expressed, essential component of cAMP-signaling.

storage

Store at +4°C

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Suppliers

Global( 66)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3444 55
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4991 55
Supplier Advantage
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
BOC Sciences 65
Sigma-Aldrich 80
EMMX Biotechnology LLC 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
MQ (shanghai) Pharmaceuticals Co., Ltd. 55

View Lastest Price from (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide pictures 2020-01-09 (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
330676-02-3
 US $0.01 / KG 500g 98%; 99% 500g；1kg； 10kg; 25kg Career Henan Chemical Co
(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide KH 7 (E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide sAC inhibitor KH7 Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide inhibit,KH 7,Adenylate Cyclase,Adenylyl cyclase,KH7,Inhibitor,KH-7 330676-02-3