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Isoescin IB

Chemical Properties Pharmacological Action Escin Ia & Isoescin Ib
Isoescin IB
Isoescin IB structure
CAS No.
219944-46-4
Chemical Name:
Isoescin IB
Synonyms
Aescin D;Escin IVb;Isoescin Ib;Isoescin IB(Isoaescin IB);Escin Impurity 4(Isoescin IB);β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-;(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid
CBNumber:
CB72554315
Molecular Formula:
C55H86O24
Formula Weight:
1131.26
MOL File:
219944-46-4.mol

Isoescin IB Properties

Boiling point:
1148.1±65.0 °C(Predicted)
Density 
1.46
pka
2.63±0.70(Predicted)
FDA UNII
63505RAS3F

Isoescin IB price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 300477 Isoescin IB 219944-46-4 5mg $490 2021-12-16 Buy
Biorbyt Ltd orb259321 Isoescin IB 95% 219944-46-4 10 mg $552.5 2021-12-16 Buy
Biosynth Carbosynth FI145247 Isoescin IB 219944-46-4 2 mg $98.76 2021-12-16 Buy
Biosynth Carbosynth FI145247 Isoescin IB 219944-46-4 5 mg $197.5 2021-12-16 Buy
Biosynth Carbosynth FI145247 Isoescin IB 219944-46-4 25 mg $687.5 2021-12-16 Buy

Isoescin IB Chemical Properties,Uses,Production

Chemical Properties

The saponins found in escin exist in two forms, β-escin and α-escin, which can be distinguished by melting point, hemolytic index, specific rotation and solubility in water. β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts.

Pharmacological Action

Escin exhibits remarkable anti-inflammatory, anti-edematous and vasoprotective properties in a dose-dependent manner which are quite evident at 10-6–10-7 M. Escin has been traditionally used to treat conditions such as chronic venous insufficiency, hemorrhoids, inflammation and cerebral ischemic damage.

Escin Ia & Isoescin Ib

As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity. Similar to isoescin Ia is the isomer of escin Ia, Isoescin Ib is an isomer of escin Ib. Both of them were found to be isomerizable in vitro. Escin Ib and isoescin Ib exhibits stronger pharmacological activity than escin Ia and isoescin Ia. As the result, pharmacokinetics study of them would be helpful for improving the practice of escin application.

Isoescin IB Preparation Products And Raw materials

Raw materials

Preparation Products


Isoescin IB Suppliers

Global( 70)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Chengdu Greenpure Biopharma CO.,Ltd
18283602253
jancyzheng@gcgreenpure.com CHINA 1257 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com China 2712 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14344 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Wuhan ChemNorm Biotech Co.,Ltd.
18971486879 +86-27-8439 4403
+86-27-8439 4403 sales@chemnorm.com CHINA 2936 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19231 58

Related articles

  • What is Isoescin IB?
  • Escin (aescin) is a mixture of triterpene saponins and constitutes the major active ingredient in horse chestnut (Aesculus hip....
  • Feb 13,2020

View Lastest Price from Isoescin IB manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-06 Aescin D
219944-46-4
US $1.00 / kg 1kg 95%-99% 1000kg Career Henan Chemical Co

219944-46-4(Isoescin IB)Related Search:


  • Aescin D
  • Escin IVb
  • Isoescin Ib
  • Isoescin IB(Isoaescin IB)
  • (3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid
  • Escin Impurity 4(Isoescin IB)
  • β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-
  • 219944-46-4
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