2-FLUOROPALMITIC ACID
- CAS No.
- 16518-94-8
- Chemical Name:
- 2-FLUOROPALMITIC ACID
- Synonyms
- 2-FLUOROPALMITIC ACID;2-FLUOROHEXADECANOIC ACID;JGRIJJOLCNCSNX-UHFFFAOYSA-N;Hexadecanoic acid, 2-fluoro-
- CBNumber:
- CB7256741
- Molecular Formula:
- C16H31FO2
- Molecular Weight:
- 274.41
- MDL Number:
- MFCD00216145
- MOL File:
- 16518-94-8.mol
2-FLUOROPALMITIC ACID price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 90380 | 2-fluoro Palmitic Acid ≥98% | 16518-94-8 | 5mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 90380 | 2-fluoro Palmitic Acid ≥98% | 16518-94-8 | 10mg | $115 | 2024-03-01 | Buy |
| Cayman Chemical | 90380 | 2-fluoro Palmitic Acid ≥98% | 16518-94-8 | 25mg | $272 | 2024-03-01 | Buy |
| Cayman Chemical | 90380 | 2-fluoro Palmitic Acid ≥98% | 16518-94-8 | 50mg | $513 | 2024-03-01 | Buy |
| ApexBio Technology | C3924 | 2-fluoroPalmiticAcid | 16518-94-8 | 50mg | $432 | 2021-12-16 | Buy |
2-FLUOROPALMITIC ACID Chemical Properties,Uses,Production
Definition
ChEBI: 2-fluorohexadecanoic acid is a long-chain fatty acid and a fluoro fatty acid.
Biological Activity
2-fluoropalmitic acid inhibits sphingosine biosynthesis and long-chain acyl-coa synthetase [1]. the length of the carbon chain of the fatty acid species defines the substrate specificity for the different acyl-coa synthetases (acs).mammalian long-chain acyl-coa synthetases (acsl) activate fatty acids with chain lengths of 12 to 20 carbon atoms. the long-chain acyl-coa synthetase mrna is expressed virtually in heart, liver, and epididymal adipose tissues and, to a much lesser extent, in brain, small intestine, and lung [2].palmitic acid was a selective cytotoxic substance extracted from the marine algal. at concentrations ranging from 12.5 to 50 μg/ml, palmitic acid showed selective cytotoxicity to human leukemic cells, but no cytotoxicity to normal hdf cells. palmitic acid (50 μg/ml) induced apoptosis in the human leukemic cell line molt-4. palmitic acid also showed in vivo antitumor activity in mice [3]. 2-fluoropalmitic acid showed an inhibitory effect on sphingosine biosynthesis and long-chain acyl-coa synthetase with an ic50 value of 0.2 mm [1].
References
[1] soltysiak r m, matsuura f, bloomer d, et al. d, l-α-fluoropalmitic acid inhibits sphingosine base formation and accumulates in membrane lipids of cultured mammalian cells[j]. biochimica et biophysica acta (bba)-lipids and lipid metabolism, 1984, 792(2): 214-226.
[2] suzuki h, kawarabayasi y, kondo j, et al. structure and regulation of rat long-chain acyl-coa synthetase[j]. journal of biological chemistry, 1990, 265(15): 8681-8685.
[3] harada h, yamashita u, kurihara h, et al. antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga[j]. anticancer research, 2001, 22(5): 2587-2590.
2-FLUOROPALMITIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-FLUOROPALMITIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2210 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |