ANTI-HUMAN COMPLEMENT C3
- CAS No.
- Chemical Name:
- ANTI-HUMAN COMPLEMENT C3
- Synonyms
- ANTI-C3C;ANTI-HUMAN C3;ANTI-C3, NEPH;ANTI-C3, HUMAN;ANTI-C3C, HUMAN;ANTI-C3A (HUMAN);ANTI-COMPLEMENT C3;ANTI-COMPLEMENT C3C;ANTI HUMAN C3, SHEEP;ANTI-C3, HUMAN (GOAT)
- CBNumber:
- CB7261123
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00162189
- MOL File:
- Mol file
ANTI-HUMAN COMPLEMENT C3 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | GW20073F | Anti-Complement C3 antibody produced in chicken affinity isolated antibody, buffered aqueous solution | 50μG | $362 | 2023-06-20 | Buy | |
| American Custom Chemicals Corporation | ATB0010651 | ANTI-COMPLEMENT C3 95.00% | 5MG | $499.91 | 2021-12-16 | Buy |
ANTI-HUMAN COMPLEMENT C3 Chemical Properties,Uses,Production
Uses
Anti-complement C3 antibody produced in chicken has been used in immunoblot analysis.
General Description
The complement factor 3 (C3) gene, with 41 exons spanning 41kb on genomic DNA, is mapped to human chromosome 19p13.3. It is the third component of complement and is characterized with α and β chains. It is one of the most abundant complement protein in the serum.
Biochem/physiol Actions
Complement factor 3 (C3) plays an essential role in the activation of the complement system. C3-convertase (C4b2a) cleaves C3 complement into C3a and C3b. C3b can bind covalently, through its reactive thioester, to cell surface carbohydrates or immune complexes and involve in the self-activation loop of complement activation via the alternate pathway. In addition, C3b also interacts with C3 convertases (C4b2a or C3bBb) to form the C5 convertase, which cleaves complement factor 5 into C5a and C5b. Derived from proteolytic degradation of complement C3, C3a (anaphylatoxin) facilitates the recruitment of inflammatory cells. C3a stimulates smooth muscle contraction, enhances vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Mutation in C3 gene leads to the development of age-related macular degeneration (AMD).
ANTI-HUMAN COMPLEMENT C3 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN COMPLEMENT C3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |