ChemicalBook >> CAS DataBase List >>MBX2982
MBX2982
- CAS No.
- 1037792-44-1
- Chemical Name:
- MBX2982
- Synonyms
- CS-485;MBX2982;SAR-260093;MBX-2982, >=98%;MBX2982 / MBX-2982;MBX-2982 (SAR260093);MBX-2982;MBX 2982;MBX2982;2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole;4-((4-(1H-Tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole;pyrimidine, 5-ethyl-2-[4-[4-[[4-(1h-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-
- CBNumber:
- CB72620009
- Molecular Formula:
- C22H24N8OS
- Molecular Weight:
- 448.54
- MDL Number:
- MFCD22628771
- MOL File:
- 1037792-44-1.mol
- MSDS File:
- SDS
Last updated:2023-09-20 16:43:00
| Boiling point | 683.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.42 |
| storage temp. | Store at -20°C |
| solubility | DMSO : 50 mg/mL (111.47 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| pka | 5.39±0.42(Predicted) |
| FDA UNII | B5TRY67L51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
MBX2982 price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22206 | MBX-2982 ≥98% | 1037792-44-1 | 5mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 22206 | MBX-2982 ≥98% | 1037792-44-1 | 10mg | $275 | 2024-03-01 | Buy |
| Cayman Chemical | 22206 | MBX-2982 ≥98% | 1037792-44-1 | 25mg | $606 | 2024-03-01 | Buy |
| Cayman Chemical | 22206 | MBX-2982 ≥98% | 1037792-44-1 | 50mg | $844 | 2024-03-01 | Buy |
| Biorbyt Ltd | orb181053 | MBX-2982 >98% | 1037792-44-1 | 100mg | $838.1 | 2021-12-16 | Buy |
MBX2982 Chemical Properties,Uses,Production
Description
MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits hepatic lipid accumulation in wild-type, but not GPR119 knockout, mice fed a high-fat diet. It also increases plasma levels of glucagon-like peptide 1 (GLP-1; ) in mice when administered at a dose of 10 mg/kg prior to, and to a greater extent following, glucose administration. MBX-2982 increases glucokinase activity in an enzyme assay with an EC50 value of 45.11 μM.
MBX2982 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 84)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9347 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
MBX2982
5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine
MBX2982 / MBX-2982
5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine MBX-2982
pyrimidine, 5-ethyl-2-[4-[4-[[4-(1h-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-
2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
MBX-2982, >=98%
SAR-260093
MBX-2982;MBX 2982;MBX2982
CS-485
MBX-2982 (SAR260093)
4-((4-(1H-Tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole
1037792-44-1
Inhibitors