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(S)-(-)-WARFARIN

(S)-(-)-WARFARIN Structure
(S)-(-)-WARFARIN structure
CAS No.
5543-57-7
Chemical Name:
(S)-(-)-WARFARIN
Synonyms
Warfarin,R-;(S)-WARFARIN;(S)-(-)-WARFARIN;Warfarin S-Isomer;Warfarin Impurity 17;Warfarin Impurity 17（Warfarin S-Isomer）;s-(-)-3-acetonybenzyl)-4-hydroxycoumarin;S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN;Warfarin sodium Impurity 23 ((S)-Warfarin);2-hydroxy-3-(3-keto-1-phenyl-butyl)chromone
CBNumber:
CB7267099
Molecular Formula:
C19H16O4
Molecular Weight:
308.33
MDL Number:
MFCD00272381
MOL File:
5543-57-7.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:11
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(S)-(-)-WARFARIN Properties

Melting point ≥170 °C
storage temp. 2-8°C
solubility DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
color white to pale yellow
CAS DataBase Reference 5543-57-7(CAS DataBase Reference)
FDA UNII HP31W7FNP4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H300+H310+H330-H360D-H372-H411
Precautionary statements  P202-P264-P273-P280-P302+P352+P310-P304+P340+P310
Hazard Codes  T
Risk Statements  61-48/25-52/53
Safety Statements  53-45-61
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
NFPA 704
0
4 0

(S)-(-)-WARFARIN price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich UC214 (S)-(?)-Warfarin ≥97% (HPLC) 5543-57-7 5mg $918 2024-03-01 Buy
Sigma-Aldrich UC214 (S)-(?)-Warfarin ≥97% (HPLC) 5543-57-7 10mg $1660 2024-03-01 Buy
Cayman Chemical 13531 (-)-Warfarin ≥98% 5543-57-7 1mg $74 2024-03-01 Buy
Cayman Chemical 13531 (-)-Warfarin ≥98% 5543-57-7 5mg $241 2024-03-01 Buy
Cayman Chemical 13531 (-)-Warfarin ≥98% 5543-57-7 10mg $444 2024-03-01 Buy
Product number Packaging Price Buy
UC214 5mg $918 Buy
UC214 10mg $1660 Buy
13531 1mg $74 Buy
13531 5mg $241 Buy
13531 10mg $444 Buy

(S)-(-)-WARFARIN Chemical Properties,Uses,Production

Description

(–)-Warfarin is a component of (±)-warfarin . It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (–)-warfarin slows formation of the prothrombin complex and exhibits 6.6-fold more potent anticoagulant activity than (+)-warfarin in rats. (–)-Warfarin is primarily metabolized by the cytochrome P450 (CYP) isoform CYP2C9 and genetic polymorphisms in this enyzme, as well as other compounds metabolized by CYP2C9, increase the potential for catastrophic bleeding complications. Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.

Chemical Properties

White Solid

Uses

The S-(-)-form of Warfarin (W498500). Coumarin anticoagulant.

Uses

(S)-(?)-Warfarin has been used in cell cultures.

Definition

ChEBI: (S)-warfarin is a 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one that has (S)-configuration (the racemate is warfarin, an anticoagulant drug and rodenticide). It is a conjugate acid of a (S)-warfarin(1-). It is an enantiomer of a (R)-warfarin.

General Description

Warfarin is an antagonist of vitamin K. It is an oral coumarin anticoagulant.

Biochem/physiol Actions

Warfarin is used to regulate and inhibit thromboembolic disorders. The CYP2C9 (cytochrome P450 family 2 subfamily C member 9)?protein plays a major role in the inactivation of potent S-warfarin.

(S)-(-)-WARFARIN Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-(-)-WARFARIN Suppliers

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Hebei Duling International Trade Co. LTD 		+8618032673083 sales05@hbduling.cn China 15745 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Hebei Duling International Trade Co. LTD 		58
China National Standard Pharmaceutical Corporation Limited 		58
LEAPCHEM CO., LTD. 		58
Amadis Chemical Company Limited 		58
Mainchem Co., Ltd. 55
J & K SCIENTIFIC LTD. 76

View Lastest Price from (S)-(-)-WARFARIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-WARFARIN pictures 2021-01-06 (S)-(-)-WARFARIN
5543-57-7
 US $0.37 / KG 1KG 99% 10kg/100kg Career Henan Chemica Co

5543-57-7((S)-(-)-WARFARIN)Related Search:

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(R)-6-Hydroxy Warfarin 3-(o-Hydroxyphenyl)-5-phenyl-2-cyclohexen-1-one Benzalacetone 3-[α-(2-Hydroxypropyl)benzyl]-4-hydroxycouMarin (R)-7-Hydroxy Warfarin
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Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, (S)-(-)- (8CI) 4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one S-(-)-3-Acetonybenzyl)-4-hydroxycoumarin, S-(-)-4-Hydroxy-3-(3-oxo-1-phenybutyl)-2H-1-benzopyran-2-one (-)-3-[(S)-1-Phenyl-3-oxobutyl]-4-hydroxycoumarin (-)-3-[(S)-α-Acetonylbenzyl]-4-hydroxycoumarin (-)-4-Hydroxy-3-[(S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one 2-hydroxy-3-(3-keto-1-phenyl-butyl)chromone 4-Hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one (S)-(-)-WARFARIN (S)-WARFARIN (S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE S-(-)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE (S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)-2H-1-BENZOPYRAN-2-ONE S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone Warfarin,R- (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one 4-HYDROXY-3-((S)-3-OXO-1-PHENYL-BUTYL)-CHROMEN-2-ONE s-(-)-3-acetonybenzyl)-4-hydroxycoumarin 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, (S)- 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]- (9CI) 2-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-one Warfarin S-Isomer Warfarin Impurity 17（Warfarin S-Isomer） Warfarin Impurity 17 S-(-)-WarfarinQ: What is S-(-)-Warfarin Q: What is the CAS Number of S-(-)-Warfarin Q: What is the storage condition of S-(-)-Warfarin Q: What are the applications of S-(-)-Warfarin Warfarin sodium Impurity 23 ((S)-Warfarin) 5543-57-7 C19H16O4 Intermediates & Fine Chemicals Pharmaceuticals Aromatics Chiral Reagents Heterocycles