Zileuton (sodiuM)
- CAS No.
- 118569-21-4
- Chemical Name:
- Zileuton (sodiuM)
- Synonyms
- Zileuton (sodiuM)
- CBNumber:
- CB72677043
- Molecular Formula:
- C11H13N2NaO2S
- Molecular Weight:
- 260.29
- MDL Number:
- MFCD28168553
- MOL File:
- 118569-21-4.mol
- MSDS File:
- SDS
Zileuton (sodiuM) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B1207 | Zileutonsodium | 118569-21-4 | 50mg | $189 | 2021-12-16 | Buy |
| CSNpharm | CSN17529 | ZileutonSodium | 118569-21-4 | 10mg | $48 | 2021-12-16 | Buy |
| Crysdot | CD31004380 | Zileutonsodium 98+% | 118569-21-4 | 50mg | $84 | 2021-12-16 | Buy |
| Crysdot | CD31004380 | Zileutonsodium 98+% | 118569-21-4 | 100mg | $133 | 2021-12-16 | Buy |
| CSNpharm | CSN17529 | ZileutonSodium | 118569-21-4 | 50mg | $134 | 2021-12-16 | Buy |
Zileuton (sodiuM) Chemical Properties,Uses,Production
Biological Activity
zileuton sodium is an inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes(ltb4, ltc4, ltd4 and lte4) formation with an ic50 value of 0.5μm [1].zileuton sodium has been reported to concentration-dependently inhibit the 5-lipoxygenase activity with an ic50 value of 0.5μm in rbl-1cell lysate. in addition, zileuton sodium has been found to be a potent inhibitor of ltb formation with an ic50 value of 0.6μm. furthermore, stimulated with a23187, zileuton sodium has shown a dose-dependent reduction in ltb4 and 5-hete generation in rat leukocyte with ic50 values of 0.38μm and 0.31μm, respectively. about 40-fold higher concentrations of zileuton sodium also reduced the production of pge2 with a ic50 of 16μm [1].
References
[1] carter gw1, young pr, albert dh, bouska j, dyer r, bell rl, summers jb, brooks dw. 5-lipoxygenase inhibitory activity of zileuton. j pharmacol exp ther. 1991 mar; 256(3):929-37.
Zileuton (sodiuM) Preparation Products And Raw materials
Raw materials
Preparation Products
Zileuton (sodiuM) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4604 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16111 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | chenjw@absin.cn | China | 24734 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | 12345678910 | nanfengdrug@163.com | China | 15323 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |