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(+)-Ketoconazole

(+)-Ketoconazole Structure
(+)-Ketoconazole structure
CAS No.
142128-59-4
Chemical Name:
(+)-Ketoconazole
Synonyms
(+)-R 41400;(+)-Ketoconazol;((addition))-Ketoconazole;(+) Ketoconazole,(+)Ketoconazole;Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]-
CBNumber:
CB72677058
Molecular Formula:
C26H28Cl2N4O4
Molecular Weight:
531.43
MDL Number:
MFCD00865612
MOL File:
142128-59-4.mol
Last updated:2024-07-02 08:55:16
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(+)-Ketoconazole Properties

Boiling point 753.4±60.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
solubility ≥25.5 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
pka 6.88±0.12(Predicted)
form solid
color White to off-white

(+)-Ketoconazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC K186020 (+)-Ketoconazole 142128-59-4 100mg $660 2021-12-16 Buy
ChemScene CS-1846 (+)-Ketoconazole 99.51% 142128-59-4 50mg $350 2021-12-16 Buy
ApexBio Technology B1240 (+)-Ketoconazole 142128-59-4 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ChemScene CS-1846 (+)-Ketoconazole 99.51% 142128-59-4 10mg $100 2021-12-16 Buy
ApexBio Technology B1240 (+)-Ketoconazole 142128-59-4 500mg $114 2021-12-16 Buy
Product number Packaging Price Buy
K186020 100mg $660 Buy
CS-1846 50mg $350 Buy
B1240 10mM(in 1mL DMSO) $50 Buy
CS-1846 10mg $100 Buy
B1240 500mg $114 Buy

(+)-Ketoconazole Chemical Properties,Uses,Production

Uses

(+)-Ketoconazole can be used in pharmacological activity and biological study as ketoconazole stereoisomers differentially induce CYP4501A1 in human and mouse hepatoma. Enantiomerically pure isomer of racemic Ketoconazole (K186000).

Definition

ChEBI: (2R,4S)-ketoconazole is a cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration. It is an enantiomer of a (2S,4R)-ketoconazole.

Biological Activity

(+)-ketoconazole is an imidazole anti-fungal agent, a cyp3a4 inhibitor.

(+)-Ketoconazole Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-Ketoconazole Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3466 58
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
Supplier Advantage
TargetMol Chemicals Inc. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
MedChemexpress LLC 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
LETOPHARM LIMITED 58
BOC Sciences 65
Beijing Jin Ming Biotechnology Co., Ltd. 58
Musechem 60

(+)-Ketoconazole Spectrum

(+)-Ketoconazole(142128-59-4)1HNMR
((addition))-Ketoconazole (+)-Ketoconazol (+)-R 41400 (+) Ketoconazole,(+)Ketoconazole Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]- 142128-59-4