ANTI-HUMAN CD74
- CAS No.
- Chemical Name:
- ANTI-HUMAN CD74
- Synonyms
- ANTI-CD74;ANTI-B CELL;ANTI-HUMAN CD74;ANTI-CD74, HUMAN;ANTI-CD74 (B CELL);HUMAN CD74 ANTIBODY;ANTI-CD74, HUMAN (WS IV);ANTI-B-CELLS (CD74), HUMAN;ANTI-INVARIANT CHAIN (HUMAN);ANTI-HUMAN CD74, B-CELL, LN-2
- CBNumber:
- CB7267923
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00212292
- MOL File:
- Mol file
ANTI-HUMAN CD74 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA010592 | Anti-CD74 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA010592 | Anti-CD74 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy |
ANTI-HUMAN CD74 Chemical Properties,Uses,Production
Uses
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General Description
CD74 (cluster of differentiation 74) is the invariant chain of MHC (major histocompatibility) complex class II. It was the first receptor to be recognized for macrophage migration inhibitory factor (MIF). It is a membrane receptor.
Biochem/physiol Actions
CD74 (cluster of differentiation 74) acts as the chaperone of MHC-II (major histocompatibility) and is responsible for the trafficking of MHC-II molecules in APCs (antigen presenting cells). It also interacts with non-MHC proteins and functions as a receptor for MIF (macrophage migration inhibitory factor). MIF is a pleiotropic cytokine having pro-tumorigenic and pro-inflammatory functionality. It is involved in the progression and metastasis of hematologic and solid cancers, and its up-regulation in thyroid cancer might be linked with advanced tumor stage. In patients with malignant pleural mesothelioma, the over-expression of this protein functions as an independent prognostic marker for overall survival.
ANTI-HUMAN CD74 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN CD74 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |