ChemicalBook >> CAS DataBase List >>Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
![Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Structure](CAS/GIF/118159-48-1.gif)
- CAS No.
- 118159-48-1
- Chemical Name:
- Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
- Synonyms
- SY801;CS-1347;Bicyclol;Bicyclol, SY 801;Bicyclol USP/EP/BP;Bifendate Impurity 17;Bifendate Impurity 6 (Bicyclol);Bicyclol,SY 801,SY-801,Inhibitor,Hepatitis B virus,Autophagy,inhibit,HBV;Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate;Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
- CBNumber:
- CB72693359
- Molecular Formula:
- C19H18O9
- Molecular Weight:
- 390.34
- MDL Number:
- MFCD00889471
- MOL File:
- 118159-48-1.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:15
| Boiling point | 608.1±55.0 °C(Predicted) |
|---|---|
| Density | 1.410±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO: >10mg/mL |
| pka | 13.85±0.10(Predicted) |
| form | powder |
| color | white to off-white |
| FDA UNII | 9734122TH2 |
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21551 | Bicyclol ≥98% | 118159-48-1 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 21551 | Bicyclol ≥98% | 118159-48-1 | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 21551 | Bicyclol ≥98% | 118159-48-1 | 10mg | $142 | 2024-03-01 | Buy |
| TRC | B382913 | Bicyclol | 118159-48-1 | 10mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-2968 | Bicyclol 99.97% | 118159-48-1 | 10mg | $120 | 2021-12-16 | Buy |
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Chemical Properties,Uses,Production
Description
Bicyclol is a hepatoprotective agent. It has antiviral activity against hepatitis B (HBV), reducing viral DNA and the secretion of the HBV antigens HBsAg and HBeAg by 59 and 35%, respectively, in infected 2.2.15 HepG2 cells. In vivo, bicyclol reduces duck HBV (DHBV) DNA in DHBV-infected ducks at doses ≥0.4 g/kg. It also reduces the expression of TNF-α and the accumulation of lymphocytes in the liver in a mouse model of liver injury induced by concanavalin A . Oral administration of bicyclol prior to injection of diethylnitrosamine (DEN) and phenobarbital (PB; Item Nos. 9001494 | 20987) prevents formation of DEN/PB-induced hepatocellular carcinomas. It also reduces liver fibrosis in a rat model of bile duct ligation-induced hepatic fibrosis.
Uses
Bicyclol is a novel hepatoprotectant shown to protect against liver injury by inducing Hsps, including Hsp27 and Hsp 70; Anti-inflammatory activity.
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 69)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9553 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2987 | 58 |
| Allikang Pharmaceutical Co., LTD | 0573-87390950 13806705416 | wzj@alicornpharma.com | China | 72 | 58 |
View Lastest Price from Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-31 | Bicyclol USP/EP/BP | US $1.10 / g | 1g | 0.999 | 100 Tons min | Dideu Industries Group Limited | |
![Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/a238a892-f038-4be3-a687-b8e5b58a93af.gif) |
2019-12-25 | Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
118159-48-1
|
US $0.01 / KG | 1KG | 95%-99% | 1kg; 100kg； 500kg | Career Henan Chemical Co |
-
- Bicyclol USP/EP/BP
- US $1.10 / g
- 0.999
- Dideu Industries Group Limited
-
- Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
118159-48-1
- US $0.01 / KG
- 95%-99%
- Career Henan Chemical Co
118159-48-1(Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate)Related Search:
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
Bicyclol
4, 4′-dimethoxy-2, 3, 2′, 3′-bis(methylenedioxy)-6-hydroxymethyl-6′-methoxy-carbonyl biphenyl
Bicyclol, SY 801
CS-1347
methyl 4-[5-(hydroxymethyl)-7-methoxy-1,3-benzodioxol-4-yl]-7-methoxy-1,3-benzodioxole-5-carboxylate
SY801
[4,4'-Bi-1,3-benzodioxole]-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester
Bicyclol USP/EP/BP
Bicyclol,SY 801,SY-801,Inhibitor,Hepatitis B virus,Autophagy,inhibit,HBV
Bifendate Impurity 17
Bifendate Impurity 6 (Bicyclol)
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
118159-48-1
C19H18O9