ChemicalBook >> CAS DataBase List >>Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
![Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Structure](CAS/20200611/GIF/124750-67-0.gif)
- CAS No.
- 124750-67-0
- Chemical Name:
- Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
- Synonyms
- Losartan Related compund A;Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde;2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile;2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde;[1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-;Losartan Related Compound A 4’-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1’- Biphenyl]-2-carbonitrile
- CBNumber:
- CB72709030
- Molecular Formula:
- C22H20ClN3O
- Molecular Weight:
- 377.87
- MDL Number:
- MOL File:
- 124750-67-0.mol
- MSDS File:
- SDS
Last updated:2023-07-11 08:28:12
| Melting point | 99 °C(Solv: methanol (67-56-1)) |
|---|---|
| Boiling point | 590.1±50.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 1.54±0.60(Predicted) |
| form | Solid |
| color | White to Off-White |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H317-H302 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501 |
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Chemical Properties,Uses,Production
Uses
Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is a derivative of Losartan carboxaldehyde (L470505). Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is also used as reagent to synthesize Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.
Synthesis of Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde from 2-Butyl-4-chloro-5-formylimidazole and 4-Bromomethyl-2-cyanobiphenyl
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Suppliers
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Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile
[1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-
2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde
Losartan Related compund A
Losartan Related Compound A
4’-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1’- Biphenyl]-2-carbonitrile
124750-67-0