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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

CAS No.
379270-35-6
Chemical Name:
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Synonyms
Monophenylester;TAF Impurity 3;GS7340 impurity1;GS7340 intermediate 1;Tenofovir Impurity 30;Tenofovir alafenamide-4;Tenofovir Alafenamide acid;Tenofovir Related Compound 2;Tenofovir Alafenamide Impurity 28;Tenofovir Alafenamide Impurity 18
CBNumber:
CB72729612
Molecular Formula:
C15H18N5O4P
Molecular Weight:
363.31
MDL Number:
MFCD28386144
MOL File:
379270-35-6.mol
Last updated:2024-03-22 17:12:53

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Properties

Melting point 237-239°C
Boiling point 610.1±65.0 °C(Predicted)
Density 1.53±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
pka 2.09±0.10(Predicted)
form Solid
color White to Off-White
FDA UNII 6F4V6F8MSR

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A628898 [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 379270-35-6 1g $65 2021-12-16 Buy
Ambeed A670413 Phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97% 379270-35-6 1g $84 2021-12-16 Buy
Chemenu CM138836 phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 95+% 379270-35-6 5g $421 2021-12-16 Buy
Alichem 379270356 Phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 379270-35-6 5g $590.94 2021-12-16 Buy
Chemenu CM138836 phenylhydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 95+% 379270-35-6 10g $701 2021-12-16 Buy
Product number Packaging Price Buy
A628898 1g $65 Buy
A670413 1g $84 Buy
CM138836 5g $421 Buy
379270356 5g $590.94 Buy
CM138836 10g $701 Buy

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Chemical Properties,Uses,Production

Appearance

White powder

Uses

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

Application

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

147127-20-6
108-95-2
379270-35-6
Synthesis of phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate from Tenofovir and Phenol

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Preparation Products And Raw materials

Global( 190)Suppliers
Supplier Tel Email Country ProdList Advantage
Zison Pharmaceutical (Shandong) Co., Ltd.
+86-0086-531-88259693 +86-18660188356 maguanglei@zisonpharm.com China 53 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040 sales@myuchem.com China 6711 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951 CHINA 115 55
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

View Lastest Price from phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate pictures 2024-04-19 Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
US $100.00-800.00 / kg 0.10000000149011612kg 98% 2MT per month Anhui Dexinjia Biopharm Co., Ltd
Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate pictures 2024-04-19 Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
US $23.00 / KG 1KG >=99% 20mt/year Jinan Finer Chemical Co., Ltd
Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate pictures 2024-04-12 Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
US $30.00 / kg 1kg 98% 20000kg hebei hongtan Biotechnology Co., Ltd
[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Tenofovir Related Compound 2 phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate GS7340 impurity1 GS7340 intermediate 1 phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenylester Tenofovir alafenamide Intermediate Tenofovir alafenamide-4 [2-(6-Amino-purin-9- yl)-1-methyl-ethoxy methyl]-phosphonic acid monophenyl ester The intermediate of Tenofovir Alafenamide Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenyl ester (9CI) Tenofovir Impurity 30 Tenofovir alafenamide Intermediate 1 Tenofovir Alafenamide Impurity 28 TAF Impurity 3 Tenofovir Monophenyl Ester Impurity Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methyleth... Monophenylester Tenofovir Alafenamide Impurity 18 (1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-phenoxy-phosphinic acid 9-[(R)-2- (phenylphosphonomethoxy) propyl]adenine (PPMPA) Tenofovir Alafenamide Fumarate N-3 Tenofovir Alafenamide acid 379270-35-6 C15H18N5O4P Intermediate 379270-35-6