Glatiramer acetate
- CAS No.
- 147245-92-9
- Chemical Name:
- Glatiramer acetate
- Synonyms
- ProtiraMer;GlatiraMer-d7;Glatirameracetat;GaltiraMer acetate;GLATIRAMER ACETATE;Chloramine B 127-52-6;Glatiramer acetate API;Glatiramer acetate USP/EP/BP;Glatiramer acetate [USAN:BAN];Pharmaceutical Glatiramer acetate
- CBNumber:
- CB7285192
- Molecular Formula:
- C25H45N5O13
- Molecular Weight:
- 623.66
- MDL Number:
- MFCD27978717
- MOL File:
- 147245-92-9.mol
- MSDS File:
- SDS
| Melting point | >239°C (dec.) |
|---|---|
| storage temp. | Refrigerator |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 147245-92-9(CAS DataBase Reference) |
| FDA UNII | 5M691HL4BO |
| ATC code | L03AX13 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H334-H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| NFPA 704 |
|
Glatiramer acetate price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 9000571 | Glatiramer (acetate) ≥95% | 147245-92-9 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 9000571 | Glatiramer (acetate) ≥95% | 147245-92-9 | 5mg | $134 | 2024-03-01 | Buy |
| Cayman Chemical | 9000571 | Glatiramer (acetate) ≥95% | 147245-92-9 | 10mg | $231 | 2024-03-01 | Buy |
| Cayman Chemical | 9000571 | Glatiramer (acetate) ≥95% | 147245-92-9 | 25mg | $397 | 2024-03-01 | Buy |
| Usbiological | 012799 | Glatiramer Acetate | 147245-92-9 | 5mg | $276 | 2021-12-16 | Buy |
Glatiramer acetate Chemical Properties,Uses,Production
Originator
Copaxone,Teva Pharmaceuticals,Israel
Uses
Glatiramer Acetate-Dx is labelled Glatiramer Acetate (G406800) which is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.
Uses
Glatiramer acetate is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine in a molar ratio of 6:1.9:4.7:1. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.
Manufacturing Process
Glatiramer Acetate is water soluble copolypeptide with molecular weight
15,000-25,000.
Copolymer is prepared by copolymerization of the N-carboxyanhydrides of
tyrosine, alanine, lysine, and glutamic acid. The polymerisation was carried
out at ambient temperature in anhydrous dioxane with diethylamine as
initiator. Glatiramer Acetate have the ratio alanin:glutamic acid:lysine:tyrosine
= 1:6:4.54:2.
brand name
Copaxone (Teva).
Therapeutic Function
Immunomodulator
Biological Activity
Glatiramer acetate, a myelin basic protein mimetic, is an immunomodulator used for treatment of Multiple Sclerosis. Glatiramer acetate is a mixture of synthetic peptides randomly composed of glutamic acid, lysine, alanine, and tyrosine. It reduces relapse rate and disease progression in Multiple Sclerosis. Its mechanism of action is not fully understood. Glatiramer acetate generates anti-inflammatory Th2 cells, which produce neurotrophic factors.
Clinical Use
Immunomodulating drug:
Treatment for patients at a high risk of developing
multiple sclerosis and for reduction in relapses in
ambulatory patients
Metabolism
A substantial fraction of a subcutaneous dose of glatiramer is believed to be hydrolysed locally. Some of the injected dose is also presumed to enter the lymphatic system, either intact or partially hydrolysed.
Glatiramer acetate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12824 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3007 | 58 |
| Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21631 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29865 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
View Lastest Price from Glatiramer acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-14 | Glatiramer acetate
147245-92-9
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-03-13 | Glatiramer acetate
147245-92-9
|
US $0.00 / kit | 1g | 97.0%~105.0% | 1500g/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-03-07 | Glatiramer acetate
147245-92-9
|
US $10.00-3.00 / g | 10g | 99% | 300tons | Hebei Dangtong Import and export Co LTD |
-
- Glatiramer acetate
147245-92-9
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Glatiramer acetate
147245-92-9
- US $0.00 / kit
- 97.0%~105.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Glatiramer acetate
147245-92-9
- US $10.00-3.00 / g
- 99%
- Hebei Dangtong Import and export Co LTD