ChemicalBook >> CAS DataBase List >>2-CHLORO-2,2-DIFLUOROACETOPHENONE
2-CHLORO-2,2-DIFLUOROACETOPHENONE
- CAS No.
- 384-67-8
- Chemical Name:
- 2-CHLORO-2,2-DIFLUOROACETOPHENONE
- Synonyms
- 2-Chloro-2,2-difluoro-1-phenylethan-1-one;Ethanone, 2-chloro-2,2-difluoro-1-phenyl-;2-Chloro-2,2-d;CHLORODIFLUOROACETOPHENONE;à,à-difluorophenacyl chloride;à-chloro-à,à-difluoroacetophene;A-CHLORO-A,A-DIFLUOROACETOPHENONE;2-CHLORO-2,2-DIFLUOROACETOPHENONE;α,α-Difluoro-α-chloroacetophenone;ChlorodifluoroMethyl phenyl ketone
- CBNumber:
- CB7297366
- Molecular Formula:
- C8H5ClF2O
- Molecular Weight:
- 190.57
- MDL Number:
- MFCD00042123
- MOL File:
- 384-67-8.mol
- MSDS File:
- SDS
Last updated:2024-01-25 15:58:02
Melting point | 102-103 °C |
---|---|
Boiling point | 94-96 °C35 mm Hg(lit.) |
Density | 1.293 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 163 °F |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Difficult to mix. |
form | liquid |
color | Clear, colourless |
BRN | 2251448 |
CAS DataBase Reference | 384-67-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37 | |||||||||
RIDADR | UN 3334 | |||||||||
WGK Germany | 3 | |||||||||
F | 19 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29147000 | |||||||||
NFPA 704 |
|
2-CHLORO-2,2-DIFLUOROACETOPHENONE price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 792373 | 2-Chloro-2,2-difluoroacetophenone 95% | 384-67-8 | 10g | $179.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 792373 | 2-Chloro-2,2-difluoroacetophenone 95% | 384-67-8 | 1g | $63.2 | 2023-06-20 | Buy |
Alfa Aesar | L16963 | 2-Chloro-2,2-difluoroacetophenone, 96% | 384-67-8 | 1g | $96.65 | 2024-03-01 | Buy |
Alfa Aesar | L16963 | 2-Chloro-2,2-difluoroacetophenone, 96% | 384-67-8 | 5g | $377.65 | 2024-03-01 | Buy |
TRC | C423215 | 2-Chloro-2,2-difluoroacetophenone | 384-67-8 | 500mg | $75 | 2021-12-16 | Buy |
2-CHLORO-2,2-DIFLUOROACETOPHENONE Chemical Properties,Uses,Production
Description
Novel and non-ODS-based (ODS = ozone-depleting substance) difluorocarbene reagents for O- and N-difluoromethylation. PhCOCF2Cl reacts with a variety of structurally diverse phenol derivatives to produce aryl difluoromethyl ethers in good yields. PhSO2CF2Cl can react with a variety of structurally diverse phenol derivatives and N-heterocyclic compounds.
Uses
2-Chloro-2,2-difluoroacetophenone can be used:
- As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.
- As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.
- As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.
General Description
2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, and gem?-difluoromethene derived compounds.
2-CHLORO-2,2-DIFLUOROACETOPHENONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 119)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 | sales@fluoropharm.com | China | 1377 | 60 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | sales@allfluoro.com | China | 5791 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14350 | 58 |
Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | lee@unipharm-sd.com | China | 1206 | 58 |
View Lastest Price from 2-CHLORO-2,2-DIFLUOROACETOPHENONE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-02-22 | 2-Chloro-2,2-difluoroacetophenone
384-67-8
|
US $0.00 / KG | 1KG | 97.8% | 100 tons | Honest Joy Holdings Limited
|
- 2-Chloro-2,2-difluoroacetophenone
384-67-8
- US $0.00 / KG
- 97.8%
- Honest Joy Holdings Limited
384-67-8(2-CHLORO-2,2-DIFLUOROACETOPHENONE)Related Search:
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2-Chloro-2,2-difluoroacetophenone 97%
2-Chloro-2,2-difluoroacetophenone97%
2-CHLORO-2,2-DIFLUOROACETOPHENE, 96%
1-Phenyl-2,2-difluoro-2-chloroethanone
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α,α-Difluoro-α-chloroacetophenone
2-Chloro-2,2-difluoro-1-phenylethan-1-one
Ethanone, 2-chloro-2,2-difluoro-1-phenyl-
384-67-8
C6H5COCF2Cl
Fluorine series