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Vadadustat

CAS No.
1000025-07-9
Chemical Name:
Vadadustat
Synonyms
CS-2486;AKB-6548;Valdesta;PG1016548;PG-1016548;Vadadustat;PG 1016548;Vardorestat;Vadadustat 13C6;PG-1016548;AKB-6548
CBNumber:
CB73147387
Molecular Formula:
C14H11ClN2O4
Molecular Weight:
306.7
MDL Number:
MFCD30470233
MOL File:
1000025-07-9.mol
Last updated:2023-12-22 10:24:25

Vadadustat Properties

Melting point 172-174°C
Boiling point 674.6±55.0 °C(Predicted)
Density 1.461±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 4.09±0.40(Predicted)
form Solid
color Pale Beige to Light Beige
Stability Hygroscopic
FDA UNII I60W9520VV

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word  Warning
Hazard statements  H302-H373
Precautionary statements  P264-P270-P301+P312-P330-P501-P260-P314-P501

Vadadustat price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 15295 Vadadustat 1000025-07-9 5mg $62 2024-03-01 Buy
Cayman Chemical 15295 Vadadustat 1000025-07-9 10mg $109 2024-03-01 Buy
Cayman Chemical 15295 Vadadustat 1000025-07-9 25mg $239 2024-03-01 Buy
Cayman Chemical 15295 Vadadustat 1000025-07-9 50mg $357 2024-03-01 Buy
TRC V849530 Vadadustat 1000025-07-9 5mg $195 2021-12-16 Buy
Product number Packaging Price Buy
15295 5mg $62 Buy
15295 10mg $109 Buy
15295 25mg $239 Buy
15295 50mg $357 Buy
V849530 5mg $195 Buy

Vadadustat Chemical Properties,Uses,Production

Description

Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1α in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.

Uses

Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.

Vadadustat Preparation Products And Raw materials

Raw materials

Preparation Products

Vadadustat Suppliers

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9359 55
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shochem(Shanghai) Co.,Ltd
86-21-50800795 info@shochem.com CHINA 288 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29827 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Wuhan Nutra Biotechnology Co.,Ltd
+8617786394783 nutrabiotech@outlook.com China 300 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58

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  • Vadadustat is used as raw material of boronic acid and is prepared by coupling, substitution and hydrolysis reactions.
  • Dec 22,2023

View Lastest Price from Vadadustat manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Vadadustat pictures 2021-10-08 Vadadustat
1000025-07-9
US $0.00-0.00 / g 1g 98% 1000kgs Wuhan Nutra Biotechnology Co.,Ltd
Vadadustat pictures 2020-01-09 Vadadustat
1000025-07-9
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co
  • Vadadustat pictures
  • Vadadustat
    1000025-07-9
  • US $0.00-0.00 / g
  • 98%
  • Wuhan Nutra Biotechnology Co.,Ltd
  • Vadadustat pictures
  • Vadadustat
    1000025-07-9
  • US $9.80 / KG
  • ≥99%
  • Career Henan Chemical Co

Vadadustat Spectrum

Vadadustat AKB-6548; AKB 6548; AKB6548; PG-1016548; PG 1016548; PG1016548; B-506; B506; VADADUSTAT PG-1016548;AKB-6548 Vadadustat(AKB-6548/PG-1016548) Vadadustat (AKB-6548) AKB-6548 PG 1016548 PG1016548 PG-1016548 PG-1016548; PG1016548; PG 1016548; AKB-6548 CS-2486 Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]- Vadadustat USP/EP/BP Vadadustat (PG-1016548 Vadadustat 13C6 Valdesta disease,HIFs,AKB 6548,Erythropoiesis-stimulating,kidney,Inhibitor,AKB6548,inhibit,Vadadustat,HIF-PH,PG 1016548,anemia,Hypoxia-inducible factors,PG1016548,nondialysis-dependent,HIF/HIF Prolyl-Hydroxylase,chronic Vardorestat 2-(5-(3-chlorophenyl)-3-hydroxypicolinamido)acetic acid 1000025-07-9 API