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ChemicalBook >> CAS DataBase List >>(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Structure
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine structure
CAS No.
1223404-90-7
Chemical Name:
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine
Synonyms
Larotrectinib DFP-PNPP Impurity;Larotrectinib Impurity 3（Larotrectinib DFP-PNPP Impurity）;[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitropyrazolo[1,5-a]pyrimidine;(R)-5-(2-(2,5-Difluorophenyl)-1-pyrrolidinyl)-3-nitropyrazolo[1,5-a]pyrimidine;(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine;(2R)-2-(2,5-difluorophenyl)-1-{3-nitropyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine;(R)-3-nitro-5-[2-(2,5-difluorophenyl)-1-pyrrolidine]pyrazoleand[1,5-a]pyrimidine;5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitr opyrazolo[1,5-a]pyrimidine;Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-nitro-
CBNumber:
CB73167712
Molecular Formula:
C16H13F2N5O2
Molecular Weight:
345.3
MDL Number:
MFCD31922694
MOL File:
1223404-90-7.mol
Last updated:2022-12-21 16:56:50
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(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Properties

Density 1.58±0.1 g/cm3(Predicted)
pka -0.73±0.40(Predicted)
FDA UNII HK74TQK39R

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 4075DT (R)-5-(2-(2,5-Difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine 1223404-90-7 5g $593 2021-12-16 Buy
AK Scientific 4075DT (R)-5-(2-(2,5-Difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine 1223404-90-7 10g $1072 2021-12-16 Buy
Product number Packaging Price Buy
4075DT 5g $593 Buy
4075DT 10g $1072 Buy

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Chemical Properties,Uses,Production

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine synthesis

1223404-89-4
1223404-90-7
Synthesis of (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine from (2R)-2-(2,5-difluorophenyl)-1-{pyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Preparation Products And Raw materials

Raw materials

4H-Pyrazolo[1,5-a]pyrimidin-5-one (2R)-2-(2,5-difluorophenyl)-1-{pyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole 3-nitropyrazolo[1,5-a]pyrimidin-5(4H)-one 2,5-Difluorobenzaldehyde
(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE (2R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE 5-Hydroxypyrazolo[1,5-a]pyrimidine 1-Bromo-2,5-difluorobenzene

1of2

Preparation Products

LOXO-101 (sulfate)

(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Suppliers

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Shanghai Rochi Pharmaceutical Co.,Ltd. 		21-38751876 +8615000076078 info@rochipharma.com China 431 58
CR Corporation Lomited 		fred.wen@crcorporation.cn CHINA 12069 58
Jinan Ande Pharmaceutical Co.,Ltd. 		+8613256107535 andepharm@163.com CHINA 221 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Jiangxi Huihe Chemical Co., Ltd. 		+86-19189228086 +8618858568638 wuzhouding@huihecrop.com China 886 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Standardpharm Co. Ltd. 		58
career henan chemical co 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Shanghai Rochi Pharmaceutical Co.,Ltd. 		58
CR Corporation Lomited 		58
Jinan Ande Pharmaceutical Co.,Ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Jiangxi Huihe Chemical Co., Ltd. 		58

View Lastest Price from (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine pictures 2022-10-01 (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine
1223404-90-7
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine pictures 2020-02-19 (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine
1223404-90-7
 US $1.00 / KG 1KG 99% 200kgs Career Henan Chemical Co
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine (2R)-2-(2,5-difluorophenyl)-1-{3-nitropyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine 5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitr opyrazolo[1,5-a]pyrimidine Larotrectinib Impurity 3（Larotrectinib DFP-PNPP Impurity） (R)-5-(2-(2,5-Difluorophenyl)-1-pyrrolidinyl)-3-nitropyrazolo[1,5-a]pyrimidine Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-nitro- Larotrectinib DFP-PNPP Impurity [(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitropyrazolo[1,5-a]pyrimidine (R)-3-nitro-5-[2-(2,5-difluorophenyl)-1-pyrrolidine]pyrazoleand[1,5-a]pyrimidine 1223404-90-7