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Diethyl phosphite

CAS No.
762-04-9
Chemical Name:
Diethyl phosphite
Synonyms
DIETHYL PHOSPHONATE;PHOSPHONIC ACID DIETHYL ESTER;1-ethoxyphosphonoyloxyethane;DIETHYL HYDROGEN PHOSPHITE;diethylacidphosphite;Diethyl phosphite,98%;OPH(OC2H5)2;diethylfosfit;AURORA KA-1208;Diethyl phosphit
CBNumber:
CB7318904
Molecular Formula:
C4H11O3P
Molecular Weight:
138.1
MDL Number:
MFCD00044573
MOL File:
762-04-9.mol
Last updated:2023-08-15 17:37:19

Diethyl phosphite Properties

Melting point -70 °C
Boiling point 50-51 °C/2 mmHg (lit.)
Density 1.072 g/mL at 25 °C (lit.)
vapor pressure 7hPa at 20℃
refractive index n20/D 1.407(lit.)
Flash point 180 °F
form Liquid
Specific Gravity 1.072
color Colorless
Water Solubility miscible (hydrolysis)
Sensitive Moisture Sensitive
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
BRN 605759
Stability Stable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, strong bases. May decompose on exposure to moisture. Combustible.
InChIKey MJUJXFBTEFXVKU-UHFFFAOYSA-N
LogP -0.15
CAS DataBase Reference 762-04-9(CAS DataBase Reference)
FDA UNII U9X9YBA22W
NIST Chemistry Reference Phosphonic acid, diethyl ester(762-04-9)
EPA Substance Registry System Diethyl phosphite (762-04-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H317-H318
Precautionary statements  P261-P272-P280-P302+P352-P305+P351+P338-P333+P313
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  26-36/37/39-37/39-28-27
WGK Germany  1
RTECS  TG7875000
10-13-21
TSCA  Yes
HS Code  29209014
NFPA 704
2
2 0

Diethyl phosphite price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D99234 Diethyl phosphite 98% 762-04-9 250g $69.7 2024-03-01 Buy
Sigma-Aldrich 365920 Diethyl phosphite technical grade, 94% 762-04-9 1l $149 2024-03-01 Buy
Alfa Aesar 043801 Diethyl phosphite, 96% 762-04-9 250g $71.5 2023-06-20 Buy
Alfa Aesar 043801 Diethyl phosphite, 96% 762-04-9 1kg $223 2023-06-20 Buy
Strem Chemicals 93-1521 Diethylphosphite, min. 95% 762-04-9 100g $49 2024-03-01 Buy
Product number Packaging Price Buy
D99234 250g $69.7 Buy
365920 1l $149 Buy
043801 250g $71.5 Buy
043801 1kg $223 Buy
93-1521 100g $49 Buy

Diethyl phosphite Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

Diethyl phosphite is precursor used for the synthesis of various organophosphorus compounds. used to prepare the nickel chloride-diethyl phosphite system, efficient catalyst for the cross-coupling reaction between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides.

Uses

Diethyl phosphite (DEPI) is a versatile reactive intermediate used in the production of various phosphorus based substances. It may be used to prepare the nickel chloride-diethyl phosphite system, efficient catalyst for the cross-coupling reaction between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides.
It may be used:

  1. in the stereoselective synthesis of β-fluorinated alkylphosphonates
  2. Used in synthesis of homoallylic bromide
  3. Used in synthesis of series of carbazole-based α-aminophosphonates
  4. used as an extraction agent and phosphate intermediate.
  5. Used in synthesis of pesticides kitazine and phosethyl-Al as well as synthetic O, O-diethyl phosphoryl chloride.
  6. used for the synthesis of plasticizers, flame retardants, etc.
  7. Diethyl phosphite is reported to be chemical warfare agent (CWA) simulant, simulant for nerve agents sarin, soman, tabun, and VX.

Definition

ChEBI: A phosphonic ester that is the diethyl ester of phosphonic acid.

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 3327, 1988 DOI: 10.1016/0040-4039(88)85153-0

Synthesis Reference(s)

Synthetic Communications, 18, p. 665, 1988 DOI: 10.1080/00397918808077352

General Description

Diethyl phosphite is reported to be chemical warfare agent (CWA) simulant, simulant for nerve agents sarin, soman, tabun, and VX.

Global( 364)Suppliers
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View Lastest Price from Diethyl phosphite manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diethyl phosphite pictures 2023-08-15 Diethyl phosphite
762-04-9
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Diethyl phosphite pictures 2023-03-24 Diethyl phosphite
762-04-9
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
Diethyl phosphite pictures 2021-11-17 Diethyl phosphite
762-04-9
US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
diethylfosfit Ethyl phosphonate ((EtO)2HPO) Phosphorous acid diethyl Phosphorous acid hydrogen diethyl Phosphonic acid diethyl Phosphonic Acid Diethyl Ester Diethyl Phosphonate Phosphorous Acid Diethyl Ester Diethyl phosphit Phosphorous acidethyl ester two Diethylphosphite, min. 95% Diethyl phosphite technical grade Diethoxyphosphine oxide Diethyl acid phosphite Hydrogen diethyl phosphite hydrogendiethylphosphite O,O-Diethyl phosphonate OPH(OC2H5)2 PHOSPHOROUS ACID DIETHYL ESTER Diethyl hydrogen phosphonate DIETHYL PHOSPHITE AURORA KA-1208 Diethylphosphitemincolorlessliq DIETHYL PHOSPHITE, TECH., 94% O,O"-DIETHYL PHOSPHITE Diethylphosphite,min.95% Phosphonsurediethylester Diethyl phosphite, 97+% Diethyl phosphite, 95+% Tenofovir Impurity 82 Diethylphosphonat Diethyl phosphite(DEP) diethylacidphosphite PHOSPHONIC ACID DIETHYL ESTER DIETHYL HYDROGEN PHOSPHITE DIETHYL PHOSPHONATE 1-ethoxyphosphonoyloxyethane Diethyl phosphite,98% 762-04-9 15647-08-2(762-04-9) C4H11O3P C2H52PO3 C4H11O3P4 C2H5O2POH C2H5O2PHO Phosphorus Precursors Organic Phosphates/Phosphites Phosphorus Compounds Organic Building Blocks Catalysis and Inorganic Chemistry Building Blocks Organic Building Blocks Organic Phosphates/Phosphites Catalysis and Inorganic Chemistry Phosphorus Compounds Phosphorus Precursors organophosphorus compound Building Blocks Chemical Synthesis Organic Building Blocks