BIALAPHOS

BIALAPHOS structure

CAS No.: 35597-43-4

Chemical Name:: BIALAPHOS

Synonyms: Herby;C06457;SF-1293;BIALAPHOS;BIALOPHOS;bilanafos;antibioticsf1293;BIALAPHOS USP/EP/BP;Phosphinothricylalanylalanine;Phosphinothricyclalanylalanine sodium

CBNumber:: CB7329454

Molecular Formula:: C11H22N3O6P

Molecular Weight:: 323.28

MDL Number:: MFCD01939329

MOL File:: 35597-43-4.mol

MSDS File:: SDS

Last updated:2023-10-25 17:43:42

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BIALAPHOS Properties

Melting point	159-161 C
Boiling point	793.2±60.0 °C(Predicted)
Density	1.330±0.06 g/cm3(Predicted)
storage temp.	Store dry at -4
pka	2.86±0.50(Predicted)
FDA UNII	7488PCM6I2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H335-H319-H302-H315
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	26-36

BIALAPHOS price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0001706	BIALOPHOS 95.00%	35597-43-4	100MG	$1162.98	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0001706	100MG	$1162.98	Buy

BIALAPHOS Chemical Properties,Uses,Production

Description

Bilanofos is a natural product formed during the fermentation of Streptomyces hygroscopicus. It is readily soluble in water and insoluble in organic solvents such as acetone, ethanol, benzene, and hexane (9).
Bilanophos is a GS inhibitor. In the plant, bilanofos is metabolized to L-glufosinate, which inhibits the enzyme GS. Ammonium ions rapidly accumulate in the plant, and photosynthesis is inhibited, leading to rapid death of the plant. It is inactivated in soil.

History

Bialaphos[peptide derivative of PPT (PPT linked to two L-alanine moieties)] was originally isolated from cultures of Streptomyces viridochromogenes (87) and Streptomyces hygroscopicus (88). L-PPT is the natural isomer, and it was the first natural amino acid found to contain a phosphinic group. PPT strongly inhibited glutamine synthetase activity in E. coli (87), and Hoechst Ag patented it as a herbicide after its phytotoxicity was discovered (89). Bialaphos was patented as a herbicide (90) and is marketed in Japan (91). Glufosinate (ammonium salt of PPT) is the synthesized commercial product. Bialaphos is hydrolyzed by plant and soil microbial peptidases to yield the active herbicide (PPT) (92–94). PPT is also rapidly degraded, with half-life of 4 to 7 days in soils (95). In a test of 300 bacterial isolates from soil, all strains degraded L-PPT to the 2-oxo analog of PPT via transamination (96).

Definition

ChEBI: A tripeptide comprising one L-phosphinothricyl and two L-alanyl units joined in sequence.

Origin

The compound was launched as a nonselective contact herbicide in 1984.

Metabolic pathway

When 14C-bialaphos [L-2-amino-4- [(hydroxy)(methyl)phosphinoyl]butyryl-L-alanyl-L- alanine] is administered in an aqueous solution to mice, the metabolite of bialaphos which is identified as 2-amino-4-[(hydroxy)(methyl)phosphinoyl]butyric acid is excreted in the feces and urine.

Metabolism

The major metabolite following oral administration in the mouse was 2-amino-4- (hydroxy)(methyl)phosphinyl)butyric acid, which was eliminated in feces.

BIALAPHOS Preparation Products And Raw materials

Raw materials

Preparation Products

BIALAPHOS Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3635	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9409	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29322	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Hebei Duling International Trade Co. LTD	+8618032673083	sales05@hbduling.cn	China	15746	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Chongqing Chemdad Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
Hebei Duling International Trade Co. LTD	58

View Lastest Price from BIALAPHOS manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-06-25	BIALAPHOS USP/EP/BP 35597-43-4	US $1.10 / g	1g	99.9%	100 Tons Min	Dideu Industries Group Limited
2020-05-10	Bialaphos 35597-43-4	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd
2019-07-06	BIALAPHOS 35597-43-4	US $1.00 / kg	1kg	95%-99%	100kg	Career Henan Chemical Co

BIALAPHOS USP/EP/BP
35597-43-4
US $1.10 / g
99.9%
Dideu Industries Group Limited

Bialaphos
35597-43-4
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

BIALAPHOS
35597-43-4
US $1.00 / kg
95%-99%
Career Henan Chemical Co

35597-43-4(BIALAPHOS)Related Search:

Glufosinate-ammonium Bialaphos-sodium bialaphos N-acetylhydrolase BIALAPHOS SODIUM SALT BIALAPHOS

4-(hydroxymethylphosphinyl)-l-2-aminobutanoyl-l-alanyl-l-alanin antibioticsf1293 bilanafos gamma-(hydroxymethylphosphinyl)-l-alpha-aminobutyryl-l-alanyl-l-alanin gamma-(hydroxymethylphosphinyl)-l-alpha-aminobutyryl-l-alanyl-l-alanine BIALOPHOS L-2-Amino-4-[(4-hydroxy)(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine sodium salt BIALAPHOS L-2-AMINO-4-[(HYDROXY)(METHYL)PHOSPHINOYL]BUTYRYL-L-ALANYL-L-ALANINE SODIUM SALT Phosphinothricyclalanylalanine sodium 4-(Methylhydroxyphosphinyl)-L-Abu-L-Ala-L-Ala-OH Phosphinothricylalanylalanine SF-1293 2-Amino-4-(methylphosphino)butyrylalanylalanine C06457 N-{(2S)-2-aMino-4-[hydroxy(Methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine Herby TIANFUCHEM-- 35597-43-4--High purity BIALAPHOS in stock BIALAPHOS USP/EP/BP L-Alanine, (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl- γ--L-α-aminobutyryl-L-alanyl-L-alanine γ--D-α-aminobutyryl-L-alanyl-L-alanine 35597-43-4 35597-43-3 C11H23N3O6P C11H22N3O6P