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CIS-ENTACAPONE
- CAS No.
- 145195-63-7
- Chemical Name:
- CIS-ENTACAPONE
- Synonyms
- CIS-ENTACAPONE;(Z)-Entacapone;Entacapen impurity A;Entacapone-d10 (cis);Entacapone impurity A;Entacapone impurity A -I;Entacapone EP IMpurity A;Entacapone impurity A CRS;Entacapone Related CoMpound A;Z Entacapone/ EP impurity A/RC A
- CBNumber:
- CB7334326
- Molecular Formula:
- C14H15N3O5
- Molecular Weight:
- 305.29
- MDL Number:
- MFCD00869878
- MOL File:
- 145195-63-7.mol
Last updated:2023-07-12 16:52:05
| Melting point | 142-144°C |
|---|---|
| Boiling point | 526.6±50.0 °C(Predicted) |
| Density | 1.392±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Dichloromethane (Slightly), Methanol (Slightly) |
| pka | 5.15±0.50(Predicted) |
| color | Yellow to Orange |
| FDA UNII | 4X96VV9HUQ |
CIS-ENTACAPONE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001250 | Entacapone impurity A European Pharmacopoeia (EP) Reference Standard | 145195-63-7 | y0001250 | $89.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1235944 | Entacapone impurity A | 145195-63-7 | 25mg | $1210 | 2024-03-01 | Buy |
| Cayman Chemical | 28046 | cis-Entacapone | 145195-63-7 | 1mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 28046 | cis-Entacapone | 145195-63-7 | 5mg | $452 | 2024-03-01 | Buy |
| TRC | E558490 | cis-Entacapone | 145195-63-7 | 50mg | $1370 | 2021-12-16 | Buy |
CIS-ENTACAPONE Chemical Properties,Uses,Production
Description
cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone . It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.
Chemical Properties
Orange Solid
Uses
cis-Entacapone (Entacapone EP Impurity A) is the (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian.
Definition
ChEBI: 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is a hydroxycinnamic acid.
CIS-ENTACAPONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 81)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Guangzhou PI PI Biotech Inc | +86-020-81716320 +86-13602409664 | Sales@pipitech.com | China | 3635 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
145195-63-7(CIS-ENTACAPONE)Related Search:
Entacapone EP IMpurity B
(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
Entacapone
3,5-DINITROCATECHOL
Entacapone EP Impurity G
(E/Z)-3-O-Methyl Entacapone
(E)-3-O-Methyl Entacapone
TYRPHOSTIN AG 1290
3,4-Dihydroxy-5-Nitrobenzoic Acid
1of4
(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
(Z)-Entacapone
CIS-ENTACAPONE
Entacapone Related Compound A (25 mg) ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide)
Entacapone EP IMpurity A
Entacapone Related CoMpound A
Entacapone impurity A
Entacapone impurity A -I
(Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Entacapone Impurity 17(Entacapone EP Impurity A)
Entacapone Impurity 1（Entacapone EP Impurity A）
Entacapone EP Impurity A (cis-Entacapone)
Entacapone impurity A CRS
(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nit
2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2Z)-
Entacapen impurity A
Z Entacapone/ EP impurity A/RC A
(Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide
Entacapone-d10 (cis)
Entacapone Related Compound A ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide) (1235944)
Entacapone USP Related Compound A
Entacapone Z-isomer / Entacapone Related Compound-A / Entacapone EP Impurity-A
Entacapone EP Impurity A (Entacapone USP Related Compound A, cis-Entacapone)
145195-63-7
C14H15N3O5
Intermediates & Fine Chemicals
Pharmaceuticals