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4'-Methyl-2-cyanobiphenyl

4'-Methyl-2-cyanobiphenyl structure

CAS No.: 114772-53-1

Chemical Name:: 4'-Methyl-2-cyanobiphenyl

Synonyms: OTBN;2-Cyano-4'-methylbiphenyl;2MPPC;AKOS BAR-1203;Sartandiphenyl;Sartanbiphenyl;methyl diphenyl;-2-cyanobiphenyL;2-tolylbenzonitrile;2-hexylbenzonitrile

CBNumber:: CB7337004

Molecular Formula:: C14H11N

Molecular Weight:: 193.24

MDL Number:: MFCD00151805

MOL File:: 114772-53-1.mol

MSDS File:: SDS

Last updated:2025-07-14 15:27:00

Product description	Number	Pack Size	Price
2-Cyano-4'-methylbiphenyl >99.0%(GC)	C1446	10g	$33
4''-Methylbiphenyl-2-carbonitrile	M294115	25g	$185
4'-Methyl-[1,1'-biphenyl]-2-carbonitrile	OR10059	100g	$219
2'-Cyano-4-methylbiphenyl	D408	25g	$34
4'-Methyl-[1,1'-biphenyl]-2-carbonitrile	OR10059	5g	$61
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4'-Methyl-2-cyanobiphenyl Properties

Melting point	49 °C
Boiling point	>320°C
Density	1,17 g/cm³
vapor pressure	0.014Pa at 20℃
Flash point	>320°C
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Crystalline Powder
color	Off-white to beige
BRN	3605954
InChI	InChI=1S/C14H11N/c1-11-6-8-12(9-7-11)14-5-3-2-4-13(14)10-15/h2-9H,1H3
InChIKey	ZGQVZLSNEBEHFN-UHFFFAOYSA-N
SMILES	C1(C2=CC=C(C)C=C2)=CC=CC=C1C#N
LogP	3.5 at 23℃
CAS DataBase Reference	114772-53-1(CAS DataBase Reference)
FDA UNII	O417TI15TA
NIST Chemistry Reference	Benzonitrile, 2-(4-methylphenyl)-(114772-53-1)
UNSPSC Code	12352103
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08,GHS09

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H302-H312-H332-H313-H361-H372-H401-H411

Precautionary statements

P280-P201-P260-P301+P312a-P405-P501a-P261-P264-P270-P271-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-36/37/38-48/25/62/51/53-22

Safety Statements

22-26-36/37/39-36/37/45/57-20-36

WGK Germany

Hazard Note

Irritant

HS Code

27075000

NFPA 704

	1
2		0

4'-Methyl-2-cyanobiphenyl price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C1446	2-Cyano-4'-methylbiphenyl >99.0%(GC)	114772-53-1	10g	$33	2025-07-31	Buy
TRC	M294115	4''-Methylbiphenyl-2-carbonitrile	114772-53-1	25g	$185	2021-12-16	Buy
Apolloscientific	OR10059	4'-Methyl-[1,1'-biphenyl]-2-carbonitrile	114772-53-1	100g	$219	2021-12-16	Buy
AK Scientific	D408	2'-Cyano-4-methylbiphenyl	114772-53-1	25g	$34	2021-12-16	Buy
Apolloscientific	OR10059	4'-Methyl-[1,1'-biphenyl]-2-carbonitrile	114772-53-1	5g	$61	2021-12-16	Buy

Product number	Packaging	Price	Buy
C1446	10g	$33	Buy
M294115	25g	$185	Buy
OR10059	100g	$219	Buy
D408	25g	$34	Buy
OR10059	5g	$61	Buy

4'-Methyl-2-cyanobiphenyl Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.

Synthesis

4'-Methyl-2-cyanobiphenyl is prepared by the reaction of o-cyanobromobenzene and potassium (4-methylphenyl)trifluoroborate. The specific synthesis steps are as follows:
General procedure: A mixture of aryl halide (0.5 mmol), potassium aryltrifluoroborate (0.6 mmol), K2CO3 (1.0 mmol), Pd/C (5%; 0.5 mol%), ethanol (3 mL), and distilled water (1 mL) was stirred at 80 °C in air for the time indicated. The reaction mixture was added to brine (15 mL) and extracted with ethyl acetate (4×15 mL). The organic solvent was removed under vacuum, and the product was isolated by short-column chromatography.
4'-Methyl-2-cyanobiphenyl synthesis

4'-Methyl-2-cyanobiphenyl Preparation Products And Raw materials

Raw materials

POTASSIUM 4-METHYLPHENYLTRIFLUOROBORATE 2-Bromobenzonitrile

Preparation Products

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

4'-Methyl-2-cyanobiphenyl Suppliers

Global( 660)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
JUYE XIANDAI fine chemistry Co.,Ltd	+86-18958038633; +8618958038633	tony@sdhypharma.com	China	64	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8770	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20173	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13505	58
Dalian Richfortune Chemicals Co., Ltd	+86-86-411-84820922 +86-8613904096939	sales@richfortunechem.com	China	305	57

Supplier	Advantage
JUYE XIANDAI fine chemistry Co.,Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Dalian Richfortune Chemicals Co., Ltd	57

View Lastest Price from 4'-Methyl-2-cyanobiphenyl manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-09	4'-Methyl-2-cyanobiphenyl 114772-53-1			0.99		RongNa Biotechnology Co.,Ltd
2025-11-07	4'-Methyl-2-cyanobiphenyl 114772-53-1	US $0.00 / KG	1KG	99%	200mt	Jinan Finer Chemical Co., Ltd
2025-11-06	4'-Methyl-2-cyanobiphenyl 114772-53-1	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

4'-Methyl-2-cyanobiphenyl
114772-53-1
0.99
RongNa Biotechnology Co.,Ltd

4'-Methyl-2-cyanobiphenyl
114772-53-1
US $0.00 / KG
99%
Jinan Finer Chemical Co., Ltd

4'-Methyl-2-cyanobiphenyl
114772-53-1
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4'-Methyl-2-cyanobiphenyl Spectrum

4'-Methyl-2-cyanobiphenyl(114772-53-1)¹HNMR 4'-Methyl-2-cyanobiphenyl(114772-53-1)IR

114772-53-1(4'-Methyl-2-cyanobiphenyl)Related Search:

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Methyl salicylate 4-Bromomethyl-2-cyanobiphenyl Methyl acetate Thiophanate-methyl Methyl

4-(2-Cyanophenyl)benzyl alcohol 4'-(Hydroxymethyl)-[1,1'-Biphenyl]-2-Carboxylic Acid N-Methylbenzene-1,2-diamine

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2-cyanogen radical-4'-methyl biphenyl 2-[(4-methyl)pentyl]-benzonitrile 4'-Methyl-2-Cyano Diphenyl AKOS BAR-1203 4'-METHYL-2-BIPHENYLCARBONITRILE 4'-METHYL[1,1'-BIPHENYL]-2-CARBONITRILE 2-(4-TOLYL)-BENZONITRILE 2-(4-METHYLPHENYL)BENZONITRILE [2-(P-TOLYL)BENZONITRILE] 2-cyano-4methylbiphenyl 4'-Methylbiphenyl-2-carbonitrile 2-CYANO-4''-METHYLBIPHENYL (OTBN) 4''-METHYL-2-CYANO-BIPHENYL (FOR LOSARTAN) 2-CYANO-4''-METHYLBIPHENYL(SARTANBIPHENYL) 2-tolylbenzonitrile 2-CYANO-4''-METHYLBIPHENYL 99%MIN Sartandiphenyl 4-Cyanomethylbiphenyl OTBN (O-Tolybenzenitrile) Sartanbiphenyl o-(p-Tolyl)benzonitrile 4'-Methyl-2-cyanobiphenyl,98% 2-(4-Methylphenyl)benzenecarbonitrile 2MPPC 4'-Methyl-2-cyanobipheny 4'-Methyl-2-cyanobip 4'-Methyl-2-cyanobiphenyl ( OTBN ) diethyl 3-(3-acetyl-6-nitro-9H-carbazol-9-yl)propylphosphonate [1,1'-Biphenyl]-2-carbonitrile, 4'-Methyl- 4'-Methyl-2-cyanobiphenyl SynonyMs 4'-Methylbiphenyl-2-carbonitrile methyl diphenyl 2-hexylbenzonitrile Telmisartan Impurity 15 2-Cyano-4'-methylbiphenyl > 2-methyl-2-cyanobiphenyl -2-cyanobiphenyL OTBN 4’-Methyl-2-Cyano-Biphenyl 4'-Methyl-2-cyanobiphenyl ISO 9001：2015 REACH OTBN 2-Cyano-4'-methylbiphenyl Ortho Tolyl Benzonitrile (OTBN) 4'-methyl-[1,1'-biphenyl]-2-carbonitrile 4'-Methyl-2-cyanobiphenyl 2-Cyano-4-Methyl Bipheny| (OTBN) 4'-Methyl-2-cyanobiphenyl (OTBN) 4'-Methylbiphenyl-2-carbonitrile 4'-Methyl-2-cyanobiphenyl 4'-Methylbiphenyl-2-carbonitrile 114772-53-1 114772-53-21 114772-83-1 14772-53-1 2046-07-0 CH3C6H4C6H4CN Biphenyl & Diphenyl ether (intermediate of telmisartan) (intermediate of sartan) (intermediate of sartan s product) Losartan Potassium