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Fludarabine phosphate

Fludarabine phosphate
Fludarabine phosphate structure
CAS No.
75607-67-9
Chemical Name:
Fludarabine phosphate
Synonyms
FAMP;Fludura;F-ara-AMP;75607-67-9;fludarabine hcl;2-fluoro-araamp;5-Monophosphate;Fludarbine Phopshate;ludarabine phosphate;Fludarabin Phosphate
CBNumber:
CB7347825
Molecular Formula:
C10H13FN5O7P
Formula Weight:
365.2116842
MOL File:
75607-67-9.mol

Fludarabine phosphate Properties

Melting point:
203°C(dec.)(lit.)
alpha 
[α]D20 +10~+14゜(c=0.5,H2O)
Boiling point:
864.2±75.0 °C(Predicted)
Density 
2.39±0.1 g/cm3(Predicted)
RTECS 
UO7440900
storage temp. 
-20°C
solubility 
DMSO: soluble1mg/mL
pka
1.86±0.10(Predicted)
form 
Powder
color 
white
Water Solubility 
Soluble in DMSO or water at 5mg/ml
Merck 
14,4126
InChIKey
GIUYCYHIANZCFB-GFRUICAKSA-N
CAS DataBase Reference
75607-67-9(CAS DataBase Reference)
FDA UNII
1X9VK9O1SC
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H361-H362-H373-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P501a-P201-P202-P260-P263-P264-P270-P280-P301+P312+P330-P308+P313-P405-P501
WGK Germany  3
HS Code  2934990002

Fludarabine phosphate price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F9813 Fludarabine phosphate 75607-67-9 5mg $59.8 2019-12-02 Buy
Sigma-Aldrich 1272204 Fludarabine phosphate 75607-67-9 300mg $352.8 2019-12-02 Buy
TCI Chemical F0913 Fludarabine Monophosphate >98.0%(HPLC)(T) 75607-67-9 25mg $28 2019-12-02 Buy
TCI Chemical F0913 Fludarabine Monophosphate >98.0%(HPLC)(T) 75607-67-9 100mg $80 2019-12-02 Buy
Alfa Aesar J65154 9-beta-D-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate 99% 75607-67-9 250mg $34.8 2019-12-02 Buy

Fludarabine phosphate Chemical Properties,Uses,Production

Description

Fludarabine phosphate is an antimetabolite indicated for the treatment of B cell lymphocytic leukemia. It is reportedly effective in patients refractory to other therapies. Fludarabine phosphate acts by inhibiting primer RNA synthesis. Its side effects include bone marrow suppression, anemia, thrombocytopenia and neutropenia.

Chemical Properties

White or almost white, crystalline powder, hygroscopic.

Originator

Southern Research Institute (U.S.A.)

Uses

anticonvulsant

Definition

ChEBI: A purine arabinonucleoside monophosphate having 2-fluoroadenine as the nucleobase. A prodrug, it is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. Onc incorporated into DNA, 2-fluoro-ara-ATP functions as a DNA chain terminator. It is used for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to, or whose disease has progressed during, treatment with at least one standard alkylating-agent containing regimenas.

brand name

Fludara (Berlex).

Fludarabine phosphate Preparation Products And Raw materials

Raw materials

Preparation Products


Fludarabine phosphate Suppliers

Global( 337)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Beijing Yibai Biotechnology Co., Ltd
0086-182-6772-3597
sales03@yibaibiotech.com CHINA 420 58
Capot Chemical Co.,Ltd.
+86-571-85586718
+86-571-85864795 sales@capotchem.com China 19927 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21831 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22628 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 568 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24698 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30051 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 969 58
Shenzhen Nexconn Pharmatechs Ltd
15013857715
admin@nexconn.com CHINA 3160 58
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 309 58

View Lastest Price from Fludarabine phosphate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-04-29 Fludarabine phosphate
75607-67-9
US $0.00-0.00 / 公斤 1KG 99.0%+ 800 tons Shaanxi Dideu Medichem Co. Ltd
2019-07-22 Fludarabine Phosphate
75607-67-9
US $1.00 / g 1g 99% 1500 Kilogram/Kilograms per Month Cangzhou Wanyou New Material Technology Co.,Ltd
2018-12-15 Fludarabine phosphate
75607-67-9
US $1.00 / kg 1kg 99% Customized career henan chemical co

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