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Pinostrobin

CAS No.
480-37-5
Chemical Name:
Pinostrobin
Synonyms
Pistrobin;Pinostobin;PINOSTROBIN;Pinostrombin;loteprednol Impurity 18;5-Hydroxy-7-methoxyflavanone;5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one;PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL);5-Hydroxy-7-methoxyflavanone (Pinostrobin);5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin
CBNumber:
CB7350900
Molecular Formula:
C16H14O4
Molecular Weight:
270.28
MDL Number:
MFCD06858342
MOL File:
480-37-5.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:51

Pinostrobin Properties

Melting point 100°C
Boiling point 494.9±45.0 °C(Predicted)
Density 1.284±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml
form A crystalline solid
pka 7.40±0.40(Predicted)
LogP 3.591 (est)
FDA UNII SZD9LZS694

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

Pinostrobin price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22436 Pinostrobin ≥98% 480-37-5 5mg $38 2024-03-01 Buy
Cayman Chemical 22436 Pinostrobin ≥98% 480-37-5 1mg $38 2023-06-20 Buy
Cayman Chemical 22436 Pinostrobin ≥98% 480-37-5 10mg $72 2024-03-01 Buy
TRC H947653 Pinostrombin 480-37-5 10mg $1400 2021-12-16 Buy
Biosynth Carbosynth FP66572 Pinostrobin 480-37-5 50mg $150 2021-12-16 Buy
Product number Packaging Price Buy
22436 5mg $38 Buy
22436 1mg $38 Buy
22436 10mg $72 Buy
H947653 10mg $1400 Buy
FP66572 50mg $150 Buy

Pinostrobin Chemical Properties,Uses,Production

Description

Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).

Uses

Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.

Definition

ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.

90-24-4
480-37-5
Synthesis of Pinostrobin from 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE
Global( 117)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Greenpure Biopharma CO.,Ltd
18283602253 jancyzheng@gcgreenpure.com China 952 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
BOC Sciences
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Hubei Ipure Biology Co., Ltd
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Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58

View Lastest Price from Pinostrobin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	Pinostrobin pictures 2019-12-31 Pinostrobin
480-37-5
US $1.00 / KG 1KG 95-99% 1ton Career Henan Chemical Co
  • 	Pinostrobin pictures
  • Pinostrobin
    480-37-5
  • US $1.00 / KG
  • 95-99%
  • Career Henan Chemical Co
2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one 2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one Pinostobin Pistrobin Pinostrobin,(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one PINOCEMBRIN-7-METHYLETHER(RG)(PLEASE CALL) 5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one 5-Hydroxy-7-methoxyflavanone (S)-2,3-DIHYDRO-5-HYDROXY-7-METHOXY-2-PHENYL-4H-1-BENZOPYRAN-4-ONE PINOSTROBIN (S)-2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone (2S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)- Pinostrombin 5-Hydroxy-7-methoxyflavanone (Pinostrobin) 5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin loteprednol Impurity 18 480-37-5 Food Residue Analysis Food & Beverage Standards Chromatography Analytical Standards Analytical Chromatography Product Catalog Flavanones