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1-Tetralone

1-Tetralone Structure
1-Tetralone structure
CAS No.
529-34-0
Chemical Name:
1-Tetralone
Synonyms
3,4-Dihydronaphthalen-1(2H)-one;tetralone;α-Tetralone;A-TETRALONE;ALPHA-TETRALONE;3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE;3,4-DIHYDRO-1(2H)-NAPHTHALENONE;1(2H)-Naphthalenone, 3,4-dihydro-;1,2,3,4-Tetrahydronaphthalen-1-one;Tetralin-1-one
CBNumber:
CB7357499
Molecular Formula:
C10H10O
Molecular Weight:
146.19
MDL Number:
MFCD00001688
MOL File:
529-34-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:34:06
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1-Tetralone Properties

Melting point 2-7 °C(lit.)
Boiling point 113-116 °C6 mm Hg(lit.)
Density 1.099 g/mL at 25 °C(lit.)
refractive index n20/D 1.568(lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform, Ethyl Acetate (Slightly)
form Liquid
color brown
Water Solubility insoluble
BRN 607374
InChI 1S/C10H10O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6H,3,5,7H2
InChIKey XHLHPRDBBAGVEG-UHFFFAOYSA-N
SMILES O=C1CCCc2ccccc12
CAS DataBase Reference 529-34-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 6VT52A15HY
NIST Chemistry Reference 1(2H)-Naphthalenone, 3,4-dihydro-(529-34-0)
EPA Substance Registry System 1,2,3,4-Tetrahydronaphthalen-1-one (529-34-0)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn
Risk Statements  22-20/22-20/21/22
Safety Statements  23-24/25-36
WGK Germany  3
RTECS  QK4375000
TSCA  TSCA listed
HS Code  29143900
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Hazardous Substances Data 529-34-0(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 810 mg/kg LD50 dermal Rabbit > 2200 mg/kg
REACH Registrations Active
NFPA 704
1
1 0

1-Tetralone price More Price(71)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T19003 α-Tetralone 97% 529-34-0 5g $33.8 2026-04-30 Buy
Sigma-Aldrich 8.08203 1,2,3,4-Tetrahydro-1-naphthalenone for synthesis 529-34-0 100mL $79.7 2026-04-30 Buy
Sigma-Aldrich PHR3081 Phenylbutyrate Related Compound B pharmaceutical secondary standard, certified reference material 529-34-0 200MG $668 2026-04-30 Buy
Sigma-Aldrich 8.08203 1,2,3,4-Tetrahydro-1-naphthalenone for synthesis 529-34-0 250ML $154 2026-04-30 Buy
Sigma-Aldrich 1614556 Phenylbutyrate Related Compound B United States Pharmacopeia (USP) Reference Standard 529-34-0 100mg $969 2026-04-30 Buy
Product number Packaging Price Buy
T19003 5g $33.8 Buy
8.08203 100mL $79.7 Buy
PHR3081 200MG $668 Buy
8.08203 250ML $154 Buy
1614556 100mg $969 Buy

1-Tetralone Chemical Properties, Uses, Production

Chemical Properties

Clear amber to brown oily liquid

Uses

1-Tetralone is a reagent used in the synthesis of amino-pyrazolopyridines with anti-NF-κB and pro-apoptotic potential.

Production Methods

Intramolecular acylation of 4-phenylbutyric acid to 1,2,3,4-tetrahydronaphthalen-1-one (1-Tetralone).
1-Tetralone production

Synthesis Reference(s)

Tetrahedron Letters, 32, p. 4291, 1991 DOI: 10.1016/S0040-4039(00)92151-8

Purification Methods

Check the IR first. Purify α-tetralone by dissolving 20mL in Et2O (200mL), washing with H2O (100mL), 5% aqueous NaOH (100mL), H2O (100mL), 3% aqueous AcOH (100mL), 5% NaHCO3 (100mL) then H2O (100mL) and dry the ethereal layer over MgSO4. Filter, evaporate and fractionate the residue through a 6in Vigreux column (p 11) under reduced pressure to give a colourless oil (~17g) with b 90-91o/0.50.7mm. [Snyder & Werber Org Synth Coll Vol III 798 1955.] It has also been fractionated through a 0.5metre packed column with a heated jacket under reflux using a partial take-off head. It has max 247.5 and 290nm (hexane). The phenylhydrazone has m 83o. The 2,4,6-trinitrophenylhydrazone has m 247.5-248o (from EtOH). [Olson & Bader Org Synth Coll Vol IV 898 1963, Beilstein 7 H 370, 7 III 1416, 7 IV 1015.]

1-Tetralone synthesis

56685-73-5
529-34-0
Synthesis of 1-Tetralone from Spiro[1,3-dithiane-2,1'(2'H)-naphthalene], 3',4'-dihydro-

1-Tetralone Preparation Products And Raw materials

Raw materials

Chromic acetate Tin tetrachloride 4-Phenylbutyric acid 1,2,3,4-Tetrahydronaphthalene Aluminum chloride
Butyryl chloride polyphosphoric acid 5-Ethyl-2-methylpyridine Hydrogen fluoride Phosphorus pentoxide
Gamma Butyrolactone 1(2H)-Naphthalenone, 3,4-dihydro-, 2,2-dimethylhydrazone (4,4-Difluoro-3-buten-1-yl)benzene 4-Phenylbutyryl chloride

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Preparation Products

(S)-(-)-1,2,3,4-Tetrahedro-naphthoic acid γ-Hydroxybutyrophenone 7-Hydroxy-1-tetralone 2,3-Dihydro-1,4-naphthoquinone (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol

1-Tetralone Suppliers

Global Suppliers ( 586)
Supplier Tel Email Country ProdList Advantage
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Zhejiang zetian fine chemical co. LTD 0571-87322520 18957127338 June@zetchem.com China 382 58
BTC Pharmaceutical CO. Ltd +86-15716293042 15716293042 info@btcpharm.com China 824 55
Zhejiang Karry Pharmachem Co., Ltd. 19157666807 info@karrypharma.com China 37 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 0513-82104991 15716298942 sales11@btcpharm.com China 859 58
NINGBO JL NEW MATERIAL CO.,LTD 0574 88552218 18969899212 sales@chematerials.cn China 1512 58
Shandong Chenyi Environmental Protection Technology Co., Ltd 1856-0179988 13355310698 thezzc@outlook.com China 259 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Supplier Advantage
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Zhejiang zetian fine chemical co. LTD 58
BTC Pharmaceutical CO. Ltd 55
Zhejiang Karry Pharmachem Co., Ltd. 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 58
NINGBO JL NEW MATERIAL CO.,LTD 58
Shandong Chenyi Environmental Protection Technology Co., Ltd 58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62

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View Latest Price from 1-Tetralone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Tetralone pictures 2026-10-14 1-Tetralone
529-34-0
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
1-Tetralone pictures 2026-05-28 1-Tetralone
529-34-0
 $19.10 1KG 99% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
Dapoxetine Impurity 76 pictures 2026-03-12 Dapoxetine Impurity 76
529-34-0
 10mg 0.98 10g ShenZhen H&D Pharmaceutical Technology Co., LTD
  • 1-Tetralone pictures
  • 1-Tetralone
    529-34-0
  • $0.00
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • 1-Tetralone pictures
  • 1-Tetralone
    529-34-0
  • $19.10
  • 99%
  • Hebei Chuanghai Biotechnology Co,.LTD

1-Tetralone Spectrum

1-Tetralone(529-34-0)MS1-Tetralone(529-34-0)1HNMR1-Tetralone(529-34-0)13CNMR1-Tetralone(529-34-0)IR11-Tetralone(529-34-0)Raman

529-34-0 (1-Tetralone) Related Search:

1,2,3,4-Tetrahydronaphthalene Diethylstilbestrol Dihydromyrcenol Nabumetone Sodium 4-phenylbutyrate
Tetrahydrothiophen-3-one 4-Cyclohexylbutyric acid 3-Benzoylpropionic acid 6-methoxy-1-tetralone 6-hydroxyl-2-tetralone
4-Methyl-1-tetralone 2-Methyl-1-tetralone 3,4-Dihydro-2H-phenanthren-1-one 5-Methoxy-1-tetralone,97% 1-Methyl-2-tetralone
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KETOTETRAHYDRONAPHTHALENE 1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE 1-TETRALONE 3,4-DIHYDRO-1-(2H)NAPHTHALENEONE 1,2,3,4-Tetrahydro-1-oxonaphthalene 1-Tetralone,97% à-Tetralone 1-TETRALONE 98.5+% KETOTETRAHYDRONAPTHALENE 1-TETRALONE pure IHT-FC α-Tetralone IHT-FCα-Tetralone alpha-Tetralone, 98% 100GR alpha-Tetralone, 98% 25GR alpha-Tetralone,85% alpha-Tetralone,98% α-Tetralone ,98% 1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE FOR S alpha-Tetralone 97% 1-4 hydrogen naphthalene ketone α-Tetralone 1,2,3,4-Tetrahydrooxonaphthalene Naphthalenone,3,4-dihydro- 1,2,3,4-Tetrahydro-1-naphthalenone for synthesis 1-Oxo-1,2,3,4-tetrahydronaphthalene 1-Oxote-trahydronaphthalene 1-Oxotetralin 1-Tetrahydronathpalone Tetralole T**1-Tetralone α-TetraL 1,2,3,4-Tetrahydronaphthalen-1-One OR Alpha Tetralone Alpha-Tetralone ( CAS No. 529-34-0) α-Tetralone > α-Tetralone, 98%, for synthesis Phenylbutyrate Related Compound 1 (1-Tetralone) Sodium Phenylbutyrate Impurity 2 (Sodium Phenylbutyrate EP Impurity B) α-Tetralone/1-Tetralone 1-Tetralone 1,2,3,4-Tetrahydro-1-naphthalenone Phenylbutyrate Related Compound B (3,4-dihydronaphthalen-1(2H)-one) (1614556) 3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE 1(2H)-Naphthalenone 2,3,4-Trihydronaphthalen-1-one 3,4-dihydro-1(2h)-naphthalenon Tetralin-1-one 3,4-dihydronaphthalen-1(2H)-one (α-tetralone) Sodium Phenylbutyrate EP Impurity B 1-Tetralone or Alpha Tetralone 1-Tetrahydronaphthalenone alpha-Tetralone, 97% α-Tetralone, CAS 529-34-0 1-Tetralone (1-Oxo-1,2,3,4-tetrahydronaphthalene) 1(2H)-Naphthalenone, 3,4-dihydro- 1,2,3,4-Tetrahydronaphthalen-1-one 3,4-DIHYDRO-1(2H)-NAPHTHALENONE 3,4-Dihydronaphthalen-1(2H)-one ALPHA-TETRALONE A-TETRALONE