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1-Tetralone

1-Tetralone structure

CAS No.: 529-34-0

Chemical Name:: 1-Tetralone

Synonyms: tetralone;3,4-Dihydronaphthalen-1(2H)-one;α-Tetralone;A-TETRALONE;3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE;ALPHA-TETRALONE;Tetralin-1-one;1(2H)-Naphthalenone;2,3,4-Trihydronaphthalen-1-one;3,4-dihydro-1(2h)-naphthalenon

CBNumber:: CB7357499

Molecular Formula:: C10H10O

Molecular Weight:: 146.19

MDL Number:: MFCD00001688

MOL File:: 529-34-0.mol

MSDS File:: SDS

Last updated:2025-06-23 08:53:10

Product description	Number	Pack Size	Price
α-Tetralone 97%	T19003	5g	$31.7
1,2,3,4-Tetrahydro-1-naphthalenone for synthesis	8.08203	100mL	$74.9
Phenylbutyrate Related Compound B pharmaceutical secondary standard, certified reference material	PHR3081	200MG	$619
1,2,3,4-Tetrahydro-1-naphthalenone for synthesis	8.08203	250ML	$145
Phenylbutyrate Related Compound B United States Pharmacopeia (USP) Reference Standard	1614556	100mg	$903
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1-Tetralone Properties

Melting point	2-7 °C(lit.)
Boiling point	113-116 °C6 mm Hg(lit.)
Density	1.099 g/mL at 25 °C(lit.)
refractive index	n20/D 1.568(lit.)
Flash point	>230 °F
storage temp.	2-8°C
solubility	Chloroform, Ethyl Acetate (Slightly)
form	Liquid
color	brown
Water Solubility	insoluble
BRN	607374
InChIKey	XHLHPRDBBAGVEG-UHFFFAOYSA-N
CAS DataBase Reference	529-34-0(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	6VT52A15HY
NIST Chemistry Reference	1(2H)-Naphthalenone, 3,4-dihydro-(529-34-0)
EPA Substance Registry System	1,2,3,4-Tetrahydronaphthalen-1-one (529-34-0)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P501

Hazard Codes

Risk Statements

22-20/22-20/21/22

Safety Statements

23-24/25-36

WGK Germany

RTECS

QK4375000

TSCA

Yes

HS Code

29143900

Hazardous Substances Data

529-34-0(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 810 mg/kg LD50 dermal Rabbit > 2200 mg/kg

NFPA 704

	1
1		0

1-Tetralone price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T19003	α-Tetralone 97%	529-34-0	5g	$31.7	2025-07-31	Buy
Sigma-Aldrich	8.08203	1,2,3,4-Tetrahydro-1-naphthalenone for synthesis	529-34-0	100mL	$74.9	2025-07-31	Buy
Sigma-Aldrich	PHR3081	Phenylbutyrate Related Compound B pharmaceutical secondary standard, certified reference material	529-34-0	200MG	$619	2025-07-31	Buy
Sigma-Aldrich	8.08203	1,2,3,4-Tetrahydro-1-naphthalenone for synthesis	529-34-0	250ML	$145	2025-07-31	Buy
Sigma-Aldrich	1614556	Phenylbutyrate Related Compound B United States Pharmacopeia (USP) Reference Standard	529-34-0	100mg	$903	2025-07-31	Buy

Product number	Packaging	Price	Buy
T19003	5g	$31.7	Buy
8.08203	100mL	$74.9	Buy
PHR3081	200MG	$619	Buy
8.08203	250ML	$145	Buy
1614556	100mg	$903	Buy

1-Tetralone Chemical Properties,Uses,Production

Chemical Properties

Clear amber to brown oily liquid

Uses

1-Tetralone is a reagent used in the synthesis of amino-pyrazolopyridines with anti-NF-κB and pro-apoptotic potential.

Production Methods

Intramolecular acylation of 4-phenylbutyric acid to 1,2,3,4-tetrahydronaphthalen-1-one (1-Tetralone).
1-Tetralone production

Synthesis Reference(s)

Tetrahedron Letters, 32, p. 4291, 1991 DOI: 10.1016/S0040-4039(00)92151-8

Purification Methods

Check the IR first. Purify α-tetralone by dissolving 20mL in Et2O (200mL), washing with H2O (100mL), 5% aqueous NaOH (100mL), H2O (100mL), 3% aqueous AcOH (100mL), 5% NaHCO3 (100mL) then H2O (100mL) and dry the ethereal layer over MgSO4. Filter, evaporate and fractionate the residue through a 6in Vigreux column (p 11) under reduced pressure to give a colourless oil (~17g) with b 90-91o/0.50.7mm. [Snyder & Werber Org Synth Coll Vol III 798 1955.] It has also been fractionated through a 0.5metre packed column with a heated jacket under reflux using a partial take-off head. It has max 247.5 and 290nm (hexane). The phenylhydrazone has m 83o. The 2,4,6-trinitrophenylhydrazone has m 247.5-248o (from EtOH). [Olson & Bader Org Synth Coll Vol IV 898 1963, Beilstein 7 H 370, 7 III 1416, 7 IV 1015.]

1-Tetralone synthesis

Synthesis of 1-Tetralone from Spiro[1,3-dithiane-2,1'(2'H)-naphthalene], 3',4'-dihydro-

1-Tetralone Preparation Products And Raw materials

Raw materials

Chromic acetate Tin tetrachloride 4-Phenylbutyric acid 1,2,3,4-Tetrahydronaphthalene Aluminum chloride

Butyryl chloride Polyphosphoric acid 5-Ethyl-2-methylpyridine Hydrogen fluoride Phosphorus pentoxide

Gamma Butyrolactone 1(2H)-Naphthalenone, 3,4-dihydro-, 2,2-dimethylhydrazone (4,4-Difluoro-3-buten-1-yl)benzene 4-Phenylbutyryl chloride

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Preparation Products

(S)-(-)-1,2,3,4-Tetrahedro-naphthoic acid γ-Hydroxybutyrophenone 7-Hydroxy-1-tetralone 2,3-Dihydro-1,4-naphthoquinone (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol

1-Tetralone Suppliers

Global( 577)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2161	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58
BTC Nantong Pharmaceuticals Technology Co.,Ltd	+8618068193575	sales4@btcpharm.com	China	251	58
Zhejiang Karry Pharmachem Co., Ltd.	+8613567161161	info@karrypharma.com	China	34	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5250	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
hebei hongtan Biotechnology Co., Ltd	+852-6619 3215 +86-17731935328	sales03@chemcn.cn	China	970	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13505	58

Supplier	Advantage
Zhejiang ZETian Fine Chemicals Co. LTD	58
Coresyn Pharmatech Co., Ltd.	58
BTC Nantong Pharmaceuticals Technology Co.,Ltd	58
Zhejiang Karry Pharmachem Co., Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Anhui Ruihan Technology Co., Ltd	58
hebei hongtan Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58

1-Tetralone Derivatives: Anti-Inflammatory, MAO Inhibition, and Asymmetric Synthesis
1-Tetralone derivatives show anti-inflammatory activity via ROS inhibition, and are synthesized asymmetrically with remote qua....
Jun 23，2025

Variety Reactions Related to 1-Tetralone
1-Tetralone can be reacted with multiple chemicals.
Nov 10，2022

View Lastest Price from 1-Tetralone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-14	1-Tetralone 529-34-0	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-09-25	Dapoxetine Impurity 76 529-34-0	US $0.00-0.00 / mg	10mg	0.98	10g	ShenZhen H&D Pharmaceutical Technology Co., LTD
2025-06-20	1-Tetralone 529-34-0	US $50.00 / kg	1kg	0.99	10000	Hebei Yanxi Chemical Co., Ltd.

1-Tetralone
529-34-0
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Dapoxetine Impurity 76
529-34-0
US $0.00-0.00 / mg
0.98
ShenZhen H&D Pharmaceutical Technology Co., LTD

1-Tetralone
529-34-0
US $50.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

1-Tetralone Spectrum

1-Tetralone(529-34-0)MS 1-Tetralone(529-34-0)¹HNMR 1-Tetralone(529-34-0)¹³CNMR 1-Tetralone(529-34-0)IR1 1-Tetralone(529-34-0)Raman

529-34-0(1-Tetralone)Related Search:

1,2,3,4-Tetrahydronaphthalene Nabumetone Diethylstilbestrol Dihydromyrcenol 3-BENZOYLPROPIONIC ACID

Sodium 4-phenylbutyrate 4-CYCLOHEXYLBUTYRIC ACID Tetrahydrothiophen-3-one 6-methoxy-1-tetralone 2,3-DIHYDRO-9,10-DIHYDROXY-1,4-ANTHRACENEDIONE

5-Methoxy-1-tetralone,97% 9,10-DIHYDROBENZO[A]PYREN-7(8H)-ONE 3,4-Dihydro-2H-phenanthren-1-one 2-Methyl-1-tetralone 4-Methyl-1-tetralone

6-hydroxyl-2-tetralone 1-METHYL-2-TETRALONE Oxytetracycline dihydrate

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KETOTETRAHYDRONAPHTHALENE 1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE 1-TETRALONE 3,4-DIHYDRO-1-(2H)NAPHTHALENEONE 1,2,3,4-Tetrahydro-1-oxonaphthalene 1-Tetralone,97% 1(2H)-Naphthalenone, 3,4-dihydro- à-Tetralone 1-TETRALONE 98.5+% KETOTETRAHYDRONAPTHALENE 1-TETRALONE pure IHT-FC α-Tetralone IHT-FCα-Tetralone alpha-Tetralone, 98% 100GR alpha-Tetralone, 98% 25GR alpha-Tetralone,85% alpha-Tetralone,98% α-Tetralone ,98% 1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE FOR S alpha-Tetralone 97% 1-4 hydrogen naphthalene ketone Phenylbutyrate Related CoMpound B α-Tetralone 1,2,3,4-Tetrahydrooxonaphthalene Naphthalenone,3,4-dihydro- 1,2,3,4-Tetrahydro-1-naphthalenone for synthesis 1,2,3,4-Tetrahydronaphthalen-1-one 1-Oxo-1,2,3,4-tetrahydronaphthalene 1-Oxote-trahydronaphthalene 1-Oxotetralin 1-Tetrahydronathpalone Tetralole T**1-Tetralone α-TetraL 1,2,3,4-Tetrahydronaphthalen-1-One OR Alpha Tetralone Alpha-Tetralone ( CAS No. 529-34-0) α-Tetralone > α-Tetralone, 98%, for synthesis Phenylbutyrate Related Compound 1 (1-Tetralone) Phenylbutyrate EP Impurity B Sodium Phenylbutyrate Impurity 2 (Sodium Phenylbutyrate EP Impurity B) α-Tetralone/1-Tetralone 1-Tetralone 1,2,3,4-Tetrahydro-1-naphthalenone Phenylbutyrate Related Compound B (3,4-dihydronaphthalen-1(2H)-one) (1614556) A-TETRALONE 3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE 3,4-DIHYDRO-1(2H)-NAPHTHALENONE ALPHA-TETRALONE 1(2H)-Naphthalenone 3,4-Dihydronaphthalen-1(2H)-one 2,3,4-Trihydronaphthalen-1-one 3,4-dihydro-1(2h)-naphthalenon tetralone Tetralin-1-one α-Tetralone 3,4-dihydronaphthalen-1(2H)-one (α-tetralone) Sodium Phenylbutyrate EP Impurity B 1-Tetralone or Alpha Tetralone