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Sodium citrate

Sodium citrate
Sodium citrate structure
Chemical Name:
Sodium citrate
citreme;citnatin;FEMA 3026;citrosodna;citrosodina;citrosodine;natrocitral;SODIUM CITRATE;BUFFER SOLUTION;Citric acid 3Na
Molecular Formula:
Formula Weight:
MOL File:

Sodium citrate Properties

Melting point:
1.008 g/mL at 20 °C
storage temp. 
White to off-white
Water Solubility 
Soluble in water.
λ: 260 nm Amax: ≤0.1
184.1751; 582.1751; 582.6751; 310.545
Substances Added to Food (formerly EAFUS)
SCOGS (Select Committee on GRAS Substances)
Sodium citrate
CAS DataBase Reference
68-04-2(CAS DataBase Reference)
EWG's Food Scores
EPA Substance Registry System
Trisodium citrate (68-04-2)
  • Risk and Safety Statements
Hazard Codes  Xi,C
Risk Statements  22-40-48/20/22-41-37/38-36-35
Safety Statements  36-24/25-39-26-45-36/37/39
WGK Germany  2
RTECS  GE8300000
HS Code  29181500
Toxicity LD50 in rats, mice (mmol/kg): 6.0, 5.5 i.p. (Gruber, Halbeisen)
NFPA 704
1 1

Sodium citrate price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 83273 Citrate Concentrated Solution BioUltra, for molecular biology, 1 M in H2O 68-04-2 250ml-f $45.9 2020-08-18 Buy
Sigma-Aldrich 83273 Citrate Concentrated Solution BioUltra, for molecular biology, 1?M in H2O 250 mL $47.5 2021-03-22 Buy
Sigma-Aldrich C3674 Citric acid trisodium salt anhydrous, ≥98% (GC) 68-04-2 1kg $62.2 2021-03-22 Buy
Sigma-Aldrich PHR1416 Sodium Citrate Pharmaceutical Secondary Standard; Certified Reference Material 1 g $71 2021-03-22 Buy
Sigma-Aldrich 1613859 Sodium citrate United States Pharmacopeia (USP) Reference Standard 1 g $366 2021-03-22 Buy

Sodium citrate Chemical Properties,Uses,Production


Sodium citrate may refer to any of the sodium salts of citric acid (though most commonly the third):
Mono sodium citrate
Di sodium citrate
Tri sodium citrate
As food additives, the 3 forms of the salt are also collectively known by the E number E331.


Trisodium citrate has the chemical formula of Na3C6H5O7.It is some times referred to simply as sodium citrate, though sodium citrate can refer to any of the three sodium salts of citric acid. It possesses a saline, mildly tart flavor. For this reason, citrates of certain alkaline and alkaline earth metals (e.g. sodium and calcium citrates) are commonly known as "sour salt" (occasionally citric acid is erroneously termed sour salt).

Chemical Properties

White to off-white crystalline powder

Chemical Properties

Sodium citrate is odorless and has a pleasant, acid taste. Sodium citrate is anhydrous or contains two molecules of water of crystallization


Citric acid and its salts occur naturally in many plants and animals.


Alkalizer (systemic).


sodium citrate may be used in cosmetic formulations as an alkalizer and to bind trace metals in solutions (by means of a chelating action). It is the sodium salt of citric acid.


Sodium Citrate is a buffer and sequestrant obtained from citric acid as sodium citrate anhydrous and as sodium citrate dihydrate or sodium citrate hydrous. the crystalline products are prepared by direct crystallization from aqueous solutions. sodium citrate anhy- drous has a solubility in water of 57 g in 100 ml at 25°c, while sodium citrate dihydrate has a solubility of 65 g in 100 ml at 25°c. it is used as a buffer in carbonated beverages and to control ph in preserves. it improves the whipping properties in cream and pre- vents feathering of cream and nondairy coffee whiteners. it pro- vides emulsification and solubilizes protein in processed cheese. it prevents precipitation of solids during storage in evaporated milk. in dry soups, it improves rehydration which reduces the cooking time. it functions as a sequestrant in puddings. it functions as a complexing agent for iron, calcium, magnesium, and aluminum. typical usage levels range from 0.10 to 0.25%. it is also termed trisodium citrate.


Trisodium Citrate is a buffer and sequestrant that is the trisodium salt of citric acid. see sodium citrate.


Sodium citrate is also known as citrate of soda, the white crystals or granular powder was obtained by neutralizing citric acid with sodium carbonate. It is soluble in water but less so in alcohol. Sodium citrate was used as a preservative in albumen papers.


2 – 1 - Food
Sodium citrate is chiefly used as a food additive E331, usually for flavor or as a preservative. Sodium citrate is employed as a flavoring agent in certain varieties of club soda. Sodium citrate is common as an ingredient in Bratwurst, and is also used in commercial ready to drink beverages and drink mixes, contributing a tart flavour.
2 – 2 - Buffer
As a conjugate base of a weak acid, citrate can perform as a buffering agent or acidity regulator, resisting changes in pH. Sodium citrate is used to control acidity in some substances, such as gelatin desserts. It can be found in the mini milk containers used with coffee machines. The compound is the product of antacids, such as Alka- Seltzer, when they are dissolved in water.
2 – 3 - Medical uses
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions. It continues to be used today in blood collection tubes and for the preservation of blood in blood banks. The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism.
Sodium citrate is used to relieve discomfort in urinary tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative. It is a major component of the WHO Oral Rehydration Solution.


Produced by the neutralization of citric acid with sodium hydroxide or sodium carbonate. May be prepared in an anhydrous state or may contain 2 mole of water per mole of sodium citrate.

Food additive

Sodium citrate is some times used as an acidity regulator in drinks, and also as an emulsifier for oils when making cheese. It allows the cheeses to melt with out becoming greasy. Consider the following quote from Modernist Cuisine:
Our modernist version of mac and cheese owes its chemistry to James L. Kraft, who in 1916 patented the first American cheese slice. He showed that sodium phosphate keeps the water and fat droplets mixed when the cheese is melted. We use sodium citrate, which has the same effect and is easier to find. The resulting texture is as smooth as melted American cheese, but as complex and intense in flavor as any of your favorite cheeses.

Purification Methods

Crystallise the salt from warm water by cooling to 0o. [Beilstein 3 III 1100, 3 IV 1274.]

Sodium citrate Preparation Products And Raw materials

Raw materials

Preparation Products

Sodium citrate Suppliers

Global( 394)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 2911 55
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
02569916489 CHINA 257 58
Jiangsu Kolod Food Ingredients Co.,Ltd.
18805133257 +86-518-85110578 18805133257
+86-518-85110578 CHINA 126 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
+86-571-56059825 CHINA 8879 55
Hebei Chisure Biotechnology Co.LTD
13292891350 +86 13292890173 CHINA 1010 58
career henan chemical co
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Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 whatapp+8619930503282
86-0311-66562153 CHINA 3983 58
hdzhl biotechnology co., ltd
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View Lastest Price from Sodium citrate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-29 Sodium citrate
US $5.00 / KG 1KG 99% 30 Tons Wuhan wingroup Pharmaceutical Co., Ltd
2021-07-27 Sodium citrate
US $0.00 / KG 25KG 99% 10 tons Hengshui Haoye Chemical Co.,Ltd.
2021-07-22 Sodium citrate
US $2700.00 / T 1T 98% 50-500mt Baoji Guokang Bio-Technology Co., Ltd.

Sodium citrate Spectrum

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