ChemicalBook >> CAS DataBase List >>2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) structure

CAS No.: 1613191-99-3

Chemical Name:: 2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)

Synonyms: M-4344;VX-803;Gartisertib;VX-803(M4344 );ATR inhibitor 2;2-Amino-6-fluoro-N-[5-fluoro-4-[4-[4-(3-oxetanyl)piperazine-1-carbonyl]-1-piperidyl]-3-pyridyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-6-fluoro-N-[5-fluoro-4-[4-[[4-(3-oxetanyl)-1-piperazinyl]carbonyl]-1-piperidinyl]-3-pyridinyl]-;2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)

CBNumber:: CB73760984

Molecular Formula:: C25H29F2N9O3

Molecular Weight:: 541.55

MDL Number:: MFCD31803930

MOL File:: 1613191-99-3.mol

Last updated:2023-05-15 10:43:29

Request For Quotation

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Properties

Density	1?+-.0.1 g/cm3(Predicted)
pka	4.89±0.46(Predicted)
FDA UNII	7OM98IUD1O

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0122454	ATRinhibitor2 99.88%	1613191-99-3	5mg	$420	2021-12-16	Buy
ChemScene	CS-0122454	ATRinhibitor2 99.88%	1613191-99-3	10mg	$700	2021-12-16	Buy
ChemScene	CS-0122454	ATRinhibitor2 99.88%	1613191-99-3	50mg	$2000	2021-12-16	Buy
ChemScene	CS-0122454	ATRinhibitor2 99.88%	1613191-99-3	100mg	$3000	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0122454	5mg	$420	Buy
CS-0122454	10mg	$700	Buy
CS-0122454	50mg	$2000	Buy
CS-0122454	100mg	$3000	Buy

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Chemical Properties,Uses,Production

Uses

2-Amino-6-fluoro-N-[5-fluoro-4-[4-[[4-(oxetan-3-yl)piperazin-1-yl]carbonyl]-1-piperidyl]-3-pyridyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is an ATP-competitive and selective ATR inhibitor. Exhibits antitumor activity. Useful for monotherapy.

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) synthesis

Synthesis of 2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) from 1-(Oxetan-3-yl)piperazine and 4-Piperidinecarboxylic acid, 1-[3-[[(2-amino-6-fluoropyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-5-fluoro-4-pyridinyl]-, hydrochloride (1:1)

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Preparation Products And Raw materials

Raw materials

Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 2-amino-6-fluoro-, 2-propen-1-yl ester Tert-Butyl 1-(3-Amino-5-Fluoropyridin-4-Yl)Piperidine-4-Carboxylate Tert-Butyl 1-(3-Bromo-5-Fluoropyridin-4-Yl)Piperidine-4-Carboxylate Benzyl 4-(oxetan-3-yl)piperazine-1-carboxylate tert-Butyl piperidine-4-carboxylate

3-broMo-4-chloro-5-fluoropyridine tert-Butyl N-carbobenzoxy-4-piperidinecarboxylate 1-(Oxetan-3-yl)piperazine 2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxylicacid 3-Bromo-4-Chloro-5-Fluoropyridine Hydrochloride

1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid 3-Bromo-5-fluoropyridine

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Preparation Products

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Suppliers

Global( 15)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3420	58
Shanghai XingMo Biotechnology Co., Ltd.	13524779951	2075692521@qq.com	China	309	55
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29797	68
Kaixin Chemical (Hong Kong) Limited	010-88886666-01 13112345678	loyson@tcypharm.com	China	595	55
Wuxi AppTec	022-59987777 13552403979	jia_guoqiang@wuxiapptec.com	China	22346	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Chunchuang (Wuhan) Technology Co., Ltd	15342225168	yutianchun2007@126.com	China	10311	58
cjbscvictory	13348960310 13348960310	3003867561@qq.com	China	9946	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Shanghai XingMo Biotechnology Co., Ltd.	55
Beijing Solarbio Science & Tecnology Co., Ltd.	68
Kaixin Chemical (Hong Kong) Limited	55
Wuxi AppTec	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Chunchuang (Wuhan) Technology Co., Ltd	58
cjbscvictory	58

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) 2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide VX-803 M-4344 ATR inhibitor 2 Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-6-fluoro-N-[5-fluoro-4-[4-[[4-(3-oxetanyl)-1-piperazinyl]carbonyl]-1-piperidinyl]-3-pyridinyl]- 2-Amino-6-fluoro-N-[5-fluoro-4-[4-[4-(3-oxetanyl)piperazine-1-carbonyl]-1-piperidyl]-3-pyridyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide VX-803(M4344 ) Gartisertib 1613191-99-3 C25H29F2N9O3