SB 218795

SB 218795 structure

CAS No.: 174635-53-1

Chemical Name:: SB 218795

Synonyms: SB 218795;Sb 218795r;Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate;methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate;(-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide;(-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE;(R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID;Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-;Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-;constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3

CBNumber:: CB7376630

Molecular Formula:: C25H20N2O3

Molecular Weight:: 396.44

MDL Number:: MFCD00951240

MOL File:: 174635-53-1.mol

Last updated:2023-09-04 15:51:00

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SB 218795 Properties

Boiling point	623.7±55.0 °C(Predicted)
Density	1.237±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 40 mg/mL, soluble
form	solid
pka	11.41±0.46(Predicted)
color	white

SAFETY

Risk and Safety Statements

WGK Germany	3

SB 218795 price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	1376	SB218795 ≥99%(HPLC)	174635-53-1	10	$174	2021-12-16	Buy
Tocris	1376	SB218795 ≥99%(HPLC)	174635-53-1	50	$713	2021-12-16	Buy
TRC	S155070	SB218795	174635-53-1	50mg	$865	2021-12-16	Buy
American Custom Chemicals Corporation	API0007579	SB 218795 95.00%	174635-53-1	50MG	$1327.97	2021-12-16	Buy
ApexBio Technology	B6710	SB218795	174635-53-1	50mg	$1362	2021-12-16	Buy

Product number	Packaging	Price	Buy
1376	10	$174	Buy
1376	50	$713	Buy
S155070	50mg	$865	Buy
API0007579	50MG	$1327.97	Buy
B6710	50mg	$1362	Buy

SB 218795 Chemical Properties,Uses,Production

Uses

SB 218795 is an NK3 receptor antagonist.

Definition

ChEBI: (2R)-2-[[oxo-(2-phenyl-4-quinolinyl)methyl]amino]-2-phenylacetic acid methyl ester is a member of quinolines.

Biological Activity

Potent, selective and competitive non-peptide NK 3 receptor antagonist (K i = 13 nM at hNK 3 ). Displays 90-fold and 7000-fold selectivity over hNK 2 and hNK 1 receptors respectively. Active in vivo , inhibiting agonist-induced pupillary constriction.

SB 218795 Preparation Products And Raw materials

Raw materials

Preparation Products

SB 218795 Suppliers

Global( 33)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9901	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9440	58
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3063	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Shanghai T&W Pharmaceutical Co., Ltd.	58
EMMX Biotechnology LLC	60
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Shanghai Chaolan Chemical Technology Center	58
Shanghai Han-Xiang Chemical Co., Ltd.	58

SB 218795 Spectrum

SB 218795(174635-53-1)¹HNMR

174635-53-1(SB 218795)Related Search:

CHEMBRDG-BB 9071014 SB 218795 N-(2-HYDROXYETHYL)ISONICOTINAMIDE, 99 FOR-D-PHG-OH N-METHYL-1-QUINOLIN-4-YLMETHANAMINE

N-ME-D-PHG-OH 2-methylquinoline-4-carboxamide D(-)-AC-ALPHA-PHENYLGLYCINOL

1of2

SB 218795 (-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE (R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID (-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)- Sb 218795r methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3 Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)- Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate 174635-53-1