Basic Orange 14
- CAS No.
- 10127-02-3
- Chemical Name:
- Basic Orange 14
- Synonyms
- ACRIDINE ORANGE;BASIC ORANGE 3RN;Acridine orange, hemi salt;CI 46005;CI 46025;CI NO 46005;EUCHRYSIN GNY;BASIC ORANGE 14;Acridine Orange hemi;ACRIDINE ORANGE ZNCL2
- CBNumber:
- CB7378881
- Molecular Formula:
- C17H20Cl3N3Zn
- Molecular Weight:
- 438.1
- MDL Number:
- MFCD00081043
- MOL File:
- 10127-02-3.mol
Melting point | 165 °C |
---|---|
storage temp. | room temp |
solubility | H2O: soluble1mg/mL, clear, orange to very deep orange |
Colour Index | 46005 |
form | Solid |
pka | pKa -3.3(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);0.2(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);10.1(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain) |
color | Red brown |
PH | 3.9 (10g/l, H2O, 20℃) |
Water Solubility | soluble |
Sensitive | Hygroscopic |
BRN | 3734978 |
Stability | Stable. Incompatible with strong oxidizing agents. Protect from moisture. Hygroscopic. |
CAS DataBase Reference | 10127-02-3(CAS DataBase Reference) |
FDA UNII | F30N4O6XVV |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H341 | |||||||||
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 68-20/21/22-36/37/38 | |||||||||
Safety Statements | 45-36/37-36-26 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | AR7600000 | |||||||||
HS Code | 32041300 | |||||||||
Toxicity | A dye used to stain nucleic acids. It fluoresces at 530 nm when intercalated into double stranded DNA, or at 640 nm when ionically bound to single stranded DNA. It produces mutations, some involving reading frame shifts, other deletions or insertions and is carcinogenic. It is also known to be a dermal phototoxicant. | |||||||||
NFPA 704 |
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Basic Orange 14 price More Price(39)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 158550 | Acridine Orange hemi(zinc chloride) salt Dye content 90 % | 10127-02-3 | 10g | $91.3 | 2024-03-01 | Buy |
Sigma-Aldrich | 158550 | Acridine Orange hemi(zinc chloride) salt Dye content 90 % | 10127-02-3 | 25g | $153 | 2024-03-01 | Buy |
Sigma-Aldrich | 1.15931 | Acridine orange zinc chloride double salt (C.I.46005) for microscopy Certistain? | 10127-02-3 | 25g | $346 | 2022-05-15 | Buy |
TCI Chemical | A0132 | Basic Orange 14 | 10127-02-3 | 25g | $54 | 2023-06-20 | Buy |
Alfa Aesar | L13159 | Acridine Orange | 10127-02-3 | 5g | $30.5 | 2024-03-01 | Buy |
Basic Orange 14 Chemical Properties,Uses,Production
Chemical Properties
brown powder
Uses
Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.
Uses
Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.
General Description
Acridine orange is a metachromatic fluorescent cationic dye that permeates the cell membrane and intercalates DNA and RNA. It allows for visual detection of nucleic acids on agarose and polyacrylamide gels.
Biochem/physiol Actions
Acridine orange (AO) is a fluorescent dye with two different staining characteristics. In fixed tissues, it acts as a metachromatic dye and differentially stains DNA (green) and RNA (orange). But, in living cells it acts as a pH indicator and produce brilliant orange-red in acidic condition. AO has been used to identify apoptotic cells in drosophila embryos. Acridine Orange staining method has been used to deliver more consistent data in the micronucleus test.
Basic Orange 14 Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29322 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
View Lastest Price from Basic Orange 14 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-09-29 | Basic Orange 14
10127-02-3
|
US $1.00 / g | 5KG | 80.0% | 10kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2019-07-06 | Basic Orange 14
10127-02-3
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
- Basic Orange 14
10127-02-3
- US $1.00 / g
- 80.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
- Basic Orange 14
10127-02-3
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
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