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BMY 7378 DIHYDROCHLORIDE

BMY 7378 DIHYDROCHLORIDE structure

CAS No.: 21102-95-4

Chemical Name:: BMY 7378 DIHYDROCHLORIDE

Synonyms: CS-1419;BMY7378 HCl;BMY73782HCl;BMY 7378, >=98%;BMY7378;BMY-7378;BMY 7378 2hydrochloride;BMY 7378 DIHYDROCHLORIDE;8-(2-(4-(2-Methoxyphenyl);BMY7378,BMY-7378 dihydrochloride;BMY 7378 DIHYDROCHLORIDE;BMY 7378

CBNumber:: CB7388662

Molecular Formula:: C22H32ClN3O3

Molecular Weight:: 421.97

MDL Number:: MFCD00153771

MOL File:: 21102-95-4.mol

MSDS File:: SDS

Last updated:2023-09-20 16:43:00

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BMY 7378 DIHYDROCHLORIDE Properties

storage temp.	Inert atmosphere,Room Temperature
solubility	H₂O: soluble
form	solid
color	white
Water Solubility	Soluble to 100 mM in water
FDA UNII	KC07KV8T5O

SAFETY

Risk and Safety Statements

WGK Germany	3
RTECS	GY3996000

BMY 7378 DIHYDROCHLORIDE price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B134	BMY 7378 dihydrochloride ≥98% (HPLC), solid	21102-95-4	25mg	$304	2024-03-01	Buy
Sigma-Aldrich	B134	BMY 7378 dihydrochloride ≥98% (HPLC), solid	21102-95-4	100mg	$899	2023-01-07	Buy
Cayman Chemical	21369	BMY 7378 ≥98%	21102-95-4	10mg	$44	2024-03-01	Buy
Cayman Chemical	21369	BMY 7378 ≥98%	21102-95-4	25mg	$97	2024-03-01	Buy
Cayman Chemical	21369	BMY 7378 ≥98%	21102-95-4	50mg	$140	2024-03-01	Buy

Product number	Packaging	Price	Buy
B134	25mg	$304	Buy
B134	100mg	$899	Buy
21369	10mg	$44	Buy
21369	25mg	$97	Buy
21369	50mg	$140	Buy

BMY 7378 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

BMY 7378 dihydrochloride is a SR-1A agonist and a selective α1D-AR antagonist.

Biological Activity

5-HT 1A partial agonist and high affinity α 1D adrenoceptor antagonist (K i values are 2, 800 and 600 nM at cloned rat α 1D , rat α 1A and hamster α 1B receptors respectively). Also available as part of the α 1 -Adrenoceptor Tocriset™ .

Biochem/physiol Actions

BMY 7378 dihydrochloride is a partial 5-HT1A serotonin receptor agonist and selective α1D-adrenoceptor antagonist.

storage

Room temperature

References

1. yocca fd, hyslop dk, smith dw et al. bmy 7378, a buspirone analog with high affinity, selectivity and low intrinsic activity at the 5-ht1a receptor in rat and guinea pig hippocampal membranes. eur j pharmacol. 1987 jun 4;137(2-3):293-4.2. zemlan fp, zieleniewski-murphy a, maureen murphy r et al bmy 7378: partial agonist at spinal cord 5-ht(1a) receptors. neurochem int. 1990;16(4):515-22.3. goetz as, king hk, ward sd et al. bmy 7378 is a selective antagonist of the d subtype of alpha 1-adrenoceptors. eur j pharmacol. 1995 jan 16;272(2-3):r5-6.4. cleary l, murad k, bexis s et al. the alpha (1d)-adrenoceptor antagonist bmy 7378 is also an alpha (2c)-adrenoceptor antagonist. auton autacoid pharmacol. 2005 oct;25(4):135-41.5. sharp t, backus li, hjorth s et al. further investigation of the in vivo pharmacological properties of the putative 5-ht1a antagonist, bmy 7378. eur j pharmacol. 1990 feb 13;176(3):331-40.

BMY 7378 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

BMY 7378 DIHYDROCHLORIDE Suppliers

Global( 89)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Coresyn Pharmatech Co., Ltd.	58
TargetMol Chemicals Inc.	58

BMY 7378 DIHYDROCHLORIDE Spectrum

BMY 7378 DIHYDROCHLORIDE(21102-95-4)¹HNMR

21102-95-4(BMY 7378 DIHYDROCHLORIDE)Related Search:

Glutarimide 3,3-DIMETHYLGLUTARIMIDE 1-(2-Methoxyphenyl)piperazine BMY 7378 DIHYDROCHLORIDE 3-ETHYL-3-METHYLGLUTARIMIDE

1-(2-HYDROXYPHENYL)PIPERAZINE 1-(2-DIMETHYLAMINOETHYL)-4-METHYLPIPERAZINE 3,3-Tetramethyleneglutarimide 1-(2-Methoxyphenyl)piperazine hydrochloride 1-(2-Methoxyphenyl)piperazine hydrobromide

1-(4-CHLOROBENZYL)PIPERAZINE 4,4-DIETHYLPIPERIDINE 1-(2-PIPERIDINOETHYL)PIPERAZINE 8-AZASPIRO[4.5]DECANE 2-(4-PHENYLPIPERAZIN-1-YL)ETHANAMINE

1-(2-DIETHYLAMINOETHYL)PIPERAZINE N-(PIPERIDINOETHYL)ETHYLENEDIAMINE 3-methylglutarimide

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BMY 7378 2hydrochloride BMY 7378 DIHYDROCHLORIDE;BMY 7378 8-(2-(4-(2-Methoxyphenyl) -8-azaspiro[4.5]decane-7,9-dione dihydrochloride BMY7378 HCl 1-cyclopentanediacetimide,n-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-d n-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimided BMY 7378 DIHYDROCHLORIDE >98% PARTIAL 5- HT1A SEROTO BMY73782HCl 8-Azaspiro[4.5]decane-7,9-dione, 8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-, hydrochloride (1:2) 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride BMY7378 BMY 7378, >=98% 8-[2-[4-(METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-8-AZASPIRO[4.5]DECANE-7,9-DIONE DIHYDROCHLORIDE 8-(2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL)-8-AZASPIRO(4.5)DECANE-7,9-DIONE DIHYDROCHLORIDE BMY 7378 DIHYDROCHLORIDE 1,1-Cyclopentanediacetimide, N-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-, dihydrochloride BMY 7378 DIHYDROCHLORIDE;8-(2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL)-8-AZASPIRO(4,5)DECANE-7,9-DIONE DIHYDROCHLORIDE N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride BMY7378;BMY-7378 CS-1419 BMY 7378 DIHYDROCHLORIDE USP/EP/BP 8-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-8-azaspiro[4.... 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride (1:2) BMY7378,BMY-7378 dihydrochloride 21102-95-4 C22H33Cl2N3O3 C22H31N3O32HCl Serotonin receptor Inhibitors