ChemicalBook >> CAS DataBase List >>D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid structure

CAS No.: 103733-65-9

Chemical Name:: D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

Synonyms: D-TIC;H-D-TIC-OH;RARECHEM BK PT 0079;Icatibant Impurity 4;D-PHENYLALANINE ANALOGUE;D-1,2,3,4-Tetrahydroisoquinoline;Tetrahydroisoquinoline-3-carboxylic acid;D-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID;1,2,3,4-D-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID;1,2,3,4-TETRAHYDROISOQUINOLINE-(3R)-CARBOXYLIC ACID

CBNumber:: CB7397017

Molecular Formula:: C10H11NO2

Molecular Weight:: 177.2

MDL Number:: MFCD00144038

MOL File:: 103733-65-9.mol

MSDS File:: SDS

Last updated:2023-09-12 11:00:47

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D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Properties

Melting point	320-323 °C (decomp)
Boiling point	372.0±42.0 °C(Predicted)
Density	1.225±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Aqueous Acid (Slightly), Aqueous Base (Sparingly, Sonicated)
pka	2.21±0.20(Predicted)
form	Crystalline Powder
color	White
InChI	InChI=1S/C10H11NO2/c12-10(13)9-5-7-3-1-2-4-8(7)6-11-9/h1-4,9,11H,5-6H2,(H,12,13)/t9-/m1/s1
InChIKey	BWKMGYQJPOAASG-SECBINFHSA-N
SMILES	C1C2=C(C=CC=C2)C[C@H](C(O)=O)N1
CAS DataBase Reference	103733-65-9(CAS DataBase Reference)
FDA UNII	30WOC9CAC6

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HS Code

29334900

NFPA 704

	0
2		0

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	H29112	(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid	103733-65-9	1g	$211.65	2024-03-01	Buy
Alfa Aesar	H29112	(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid	103733-65-9	5g	$658.65	2024-03-01	Buy
Alfa Aesar	H29112	(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid	103733-65-9	250mg	$86.65	2024-03-01	Buy
TRC	T294825	(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid	103733-65-9	250mg	$50	2021-12-16	Buy
ApexBio Technology	C6784	(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylicacid	103733-65-9	100mg	$60	2021-12-16	Buy

Product number	Packaging	Price	Buy
H29112	1g	$211.65	Buy
H29112	5g	$658.65	Buy
H29112	250mg	$86.65	Buy
T294825	250mg	$50	Buy
C6784	100mg	$60	Buy

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Chemical Properties,Uses,Production

Description

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ((3R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid) is a magnetic, neutral compound. It is used as a pharmacological study to investigate the reaction mechanism and kinetics of the deuteration process. The asymmetric synthesis of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has been investigated using vinylene chloride and hydantoin as reactants. There are various parameters that affect the kinetics of this reaction such as solvent type and temperature. The nitric oxide synthase inhibitor activity of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has been studied in vitro. Results have shown that it inhibits nitric oxide synthase by binding to the heme iron of the enzyme and preventing the conversion of arginine

Chemical Properties

White solid

Uses

(R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Definition

ChEBI: D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is a member of isoquinolines.

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid synthesis

Synthesis of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid from N-(Diphenylmethylene)glycerine tert-butyl ester and 1,2-Bis(bromomethyl)benzene

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Preparation Products And Raw materials

Raw materials

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid N-(Diphenylmethylene)glycerine tert-butyl ester 1,2-Bis(bromomethyl)benzene Isobutylene

Preparation Products

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (R)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID METHYL ESTER

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Suppliers

Global( 284)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8618980456393	daisy@enlaibio.com	China	1369	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
GenicBio Limited	58
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Xiamen AmoyChem Co., Ltd	58
Xi'an Kono chem co., Ltd.,	58

View Lastest Price from D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-18	D-Tic-OH 103733-65-9	US $0.00-0.00 / kg	1kg	98%;99%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2022-10-17	D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid 103733-65-9	US $1.00 / kg	1kg	99%	50000tons	Hebei Duling International Trade Co. LTD
2020-01-06	D-TIC 103733-65-9	US $1.00 / g	1g	98%	100KG	Sichuan Jiaying Lai Technology Co.,LTD

D-Tic-OH
103733-65-9
US $0.00-0.00 / kg
98%;99%
Sichuan HongRi Pharma-Tech Co.,Ltd

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
103733-65-9
US $1.00 / kg
99%
Hebei Duling International Trade Co. LTD

D-TIC
103733-65-9
US $1.00 / g
98%
Sichuan Jiaying Lai Technology Co.,LTD

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Spectrum

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid(103733-65-9)¹HNMR

103733-65-9(D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid)Related Search:

Tetrahydrofuran Isoquinoline cis-1,2,3,6-Tetrahydrophthalic anhydride 1,2,3,4-TETRAHYDROISOQUINOLINE 1,2,3,4-Tetrahydroquinoline

Tetrahydrothiophene 1,2,3,4-Butanetetracarboxylic acid Isoquinoline-1-carboxylic acid Tetramethylammonium hydroxide pentahydrate Boc-D-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Boc-7-hydroxy-D-Tic-OH Boc-D-Tic(OH)-OH)

FMOC-TIC-OH BOC-7-HYDROXY-TIC-OH Z-D-[3S]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID,Z-L-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid FMOC-7-HYDROXY-(R)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID

L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (H-7-Hydroxy-Tic-OH) D-7-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID 2-benzyl-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid

1of4

(3R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid (R)-1,2,3,4-Tetrahydro-isoquinolin-3-carboxylic acid H-D-Tic-OH D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (3R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid≥ 99% (assay) (R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid,99%e.e. 1,2,3,4-TETRAHYDROISOQUINOLINE-(3R)-CARBOXYLIC ACID 1,2,3,4-D-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID 3-ISOQUINOLINECARBOXYLIC ACID, 1,2,3,4-TETRAHYDRO-, (3R)- (3R)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID H-D-TIC-OH D-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID D-[3R]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID D-TIC (R)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (R)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID RARECHEM BK PT 0079 D-1,2,3,4-Tetrahydroisoquinoline (R)-1,2,3,4-Tetrahydro-3-Isoquinoliceearboxylic Acid D-PHENYLALANINE ANALOGUE Tetrahydroisoquinoline-3-carboxylic acid (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-CarboxylicAci D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid USP/EP/BP 103733-65-9 D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Icatibant Impurity 4 103733-65-9 Others Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives a-amino Others Peptide Synthesis Unnatural Amino Acid Derivatives Amino Acids