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CRIMIDINE

CAS No.
535-89-7
Chemical Name:
CRIMIDINE
Synonyms
w491;w-491;crimidin;crimidina;CRIMIDINE;crimidine (bsi,iso);Crimidine: (Castrix);Adagrasib Impurity 63;3,5-DICHLOROANISOLE PESTANAL;Crimidine granules(content<2%)
CBNumber:
CB7400247
Molecular Formula:
C7H10ClN3
Molecular Weight:
171.63
MDL Number:
MFCD00055517
MOL File:
535-89-7.mol
Last updated:2024-03-14 15:18:27

CRIMIDINE Properties

Melting point 87°
Boiling point 283.13°C (rough estimate)
Density 1.2232 (rough estimate)
refractive index 1.6010 (estimate)
storage temp. 0-6°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 3.45±0.10(Predicted)
color White to Off-White
Merck 13,2615
BRN 127995
EWG's Food Scores 1-5
FDA UNII W34R2923T3
EPA Substance Registry System Crimidine (535-89-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P301+P310+P330
Hazard Codes  T+
Risk Statements  28
Safety Statements  36/37-45
RIDADR  2588
WGK Germany  2
RTECS  UV8050000
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 in rats, mice, guinea pigs (mg/kg): 1.00 ±0.06, 0.42 ±0.05, 2.66 ±0.10 i.p.; in rats (mg/kg): 1.25 ±0.10 orally (DuBois); LD50 in male, female mice (mg/kg): 1.3, 1.1 s.c.; in female mice (mg/kg): 1.2 orally (Karlog, Knudsen)

CRIMIDINE Chemical Properties,Uses,Production

Description

Crimidine is a brown, waxy solid. Molecularweight=171.65; Boiling point=about 145℃; Freezing/Melting point=87℃. Hazard Identification (based onNFPA-704 M Rating System): Health 4, Flammability 1,Reactivity 0. Slightly soluble in water.

Chemical Properties

Crimidine is a brown, waxy solid

Uses

Rodenticide.

Uses

Crimidine can be used for pesticidal utility.

Definition

ChEBI: Crimidine is a member of pyrimidines and an organohalogen compound.

General Description

Brown waxy solid or colorless crystals. Used as a rodenticide. Not registered as a pesticide in the U.S.

Reactivity Profile

CRIMIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Super toxic; probable oral lethal dose in humans is less than 5 mg/kg or less than 7 drops for a 70 kg (150 lb.) person. May cause serious central nervous system damage leading to convulsions.

Fire Hazard

CRIMIDINE emits highly toxic chloride fumes when heated to decomposition. Avoid acids and acid fumes. Very stable in neutral medium. Avoid decomposing heat.

Potential Exposure

Crimidine is used as a rodenticide. Not registered for use in the United States as a pesticide

First aid

Eye Contact: Immediately remove any contactlenses and flush with large amounts of water for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. Skin Contact: Quickly removecontaminated clothing. Immediately wash area with largeamounts of water. Seek medical attention immediately.Inhalation: Remove the person from exposure, trying toavoid rapid, jerky motions or noise. Begin rescue breathing(using universal precautions, including resuscitation mask)if breathing has stopped and CPR if heart action hasstopped. If seizures occur, begin seizure first aid measures.Call for immediate medical attention to visit the patientprior to transfer if possible. Any facility using this chemicalshould have 24-h rapid access to medical personnel withtraining and equipment for emergency treatment. All areaemployees should be trained in first aid measures forCastrix, including seizure management and CPR.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with Castrixyou should be trained on its proper handling and storage.Castrix must be stored to avoid contact with strong acids(such as hydrochloric, sulfuric, and nitric) and acid fumes,since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area.

Shipping

UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Acids and acid fumes, strong bases.

Waste Disposal

In accordance with 40CFR165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local 934 Crimidine or federal environmental control agency, or by contacting your regional EPA office.

CRIMIDINE Preparation Products And Raw materials

2-CHLORO-N,N,6-TRIMETHYLPYRIMIDIN-4-AMINE 2-CHLORO-4-DIMETHYLAMINO-6-METHYLPYRIMIDINE 2-chloor-4-dimethylamino-6-methyl-pyrimidine 2-chlor-4-dimethylamino-6-methylpyrimidin 2-chloro-4-(dimethylamino)-6-methyl-pyrimidin Crimidine granules(content<2%) CRIMIDINE crimidin crimidina 2-chloro-4-methyl-6-dimethylaminopyrimidine 2-chloro-n,n,6-trimethyl-4-pyrimidinamin 2-chloro-n,n,6-trimethylpyrimidin-4-ylamine 2-chloro-n,n-6-trimethyl-4-pyrimidinamine 2-cloro-4-dimetilamino-6-metil-pirimidina pyrimidine,2-chloro-4-dimethylamino-6-methyl w491 w-491 2-chloro-6-methylpyrimidin-4-yldimethylamine 3,5-DICHLOROANISOLE PESTANAL crimidine (bsi,iso) Crimidine: (Castrix) crimidine (ISO) 2-chloro-6-methylpyrimidin-4-yldimethylamine 2-chloro-4-dimethyladmino-6-methylpyrimidine 2-Chloro-4-(dimethylamino)-6-methylpyrimidine ,97% N,N,6-Trimethyl-2-chloro-4-pyrimidinamine 4-Pyrimidinamine, 2-chloro-N,N,6-trimethyl- Adagrasib Impurity 63 535-89-7 pharmacetical