ChemicalBook >> CAS DataBase List >>2-Phenylquinoline

2-Phenylquinoline

2-Phenylquinoline structure

CAS No.: 612-96-4

Chemical Name:: 2-Phenylquinoline

Synonyms: 830g;2-Phenylquinoline;a-Phenylquinoline;Phenylquinoline,99%;2-Phenylquinoline>Phenylquinoline, 99%;Quinoline, 2-phenyl-;2-Phenylquinoline 99%;alpha-Phenylquinoline;2-Phenylquinoline, 99+%

CBNumber:: CB7408748

Molecular Formula:: C15H11N

Molecular Weight:: 205.25

MDL Number:: MFCD00011568

MOL File:: 612-96-4.mol

MSDS File:: SDS

Last updated:2024-01-05 11:48:35

Request For Quotation

2-Phenylquinoline Properties

Melting point	84-85 °C (lit.)
Boiling point	363 °C
Density	1.1155 (rough estimate)
refractive index	1.6550 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	4.52±0.10(Predicted)
form	Crystalline Powder
color	White to light yellow
Water Solubility	SLIGHTLY SOLUBLE
λmax	258nm(lit.)
CAS DataBase Reference	612-96-4(CAS DataBase Reference)
NIST Chemistry Reference	Quinoline, 2-phenyl-(612-96-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

HS Code

29334900

NFPA 704

	0
1		0

2-Phenylquinoline price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	299650	2-Phenylquinoline 99%	612-96-4	1g	$80.9	2024-03-01	Buy
Sigma-Aldrich	299650	2-Phenylquinoline 99%	612-96-4	5g	$384	2024-03-01	Buy
TCI Chemical	P2057	2-Phenylquinoline >98.0%(GC)(T)	612-96-4	1g	$66	2024-03-01	Buy
TCI Chemical	P2057	2-Phenylquinoline >98.0%(GC)(T)	612-96-4	5g	$223	2024-03-01	Buy
Alfa Aesar	H31920	2-Phenylquinoline, 99+%	612-96-4	1g	$70.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
299650	1g	$80.9	Buy
299650	5g	$384	Buy
P2057	1g	$66	Buy
P2057	5g	$223	Buy
H31920	1g	$70.65	Buy

2-Phenylquinoline Chemical Properties,Uses,Production

Description

2-Phenylquinoline is the major quinoline alkaloid of Galipea iongiflora, a Bolivian plant used as treatment for cutaneous leishmaniasis. Antinociceptive properties of 2-phenylquinoline isolated from the bark of Galipea iongiflora against different models of pain in mice were evaluated.

Chemical Properties

white to light yellow crystalline powder

Uses

2-Phenylquinoline was used in quantitative structure-activity relationship (QSAR) analyses of estrogen receptor β-selective ligands.

Preparation

Synthesis of 2-phenylquinoline: Quinoline (1.0 g, 7.742 mmol) and phenyl lithium (2.30 mL, 2 M, 23.22 mmol) were reacted according to general procedure. Purification of the residue by silica gel column chromatography (EtOAc:MeOH:Et3N; 10-30:1:1 or PhMe:MeOH:Et3N; 10:1:1) gave 2-phenylquinoline (0.66 g, 42%) as an orange solid.
Aniline (0.140 g, 1.50 mmol) and cinnamaldehyde (0.132 g, 1.00 mmol) were dissolved in toluene in a reaction vial equipped with a magnetic stirrer bar, followed by the addition of K10 (0.50 g). The reaction mixture was heated at a temperature of 110 ?C for 3 hours. After completion of the reaction, the crude product was purified by column chromatography over silica gel eluting with a mixture of Hexane : Ethyl acetate (20:1) to produce 2-Phenylquinoline as a yellow solid (0.044 g, 21%); (m.p. 82-84 ?C) (lit. 84-85 °C); Rf 0.67 (20:1 hexane:ethyl acetate);
1H NMR (400 MHz, CDCl3) δH 7.46-7.51 (1H, m, H-4’), 7.53-7.56 (3H, m, H-6, 3’, 5’), 7.73- 7.77 (1H, m, H-7), 7.85 (1H, d, J = 8.31 Hz, H-5), 7.88-7.91 (1H, d, J = 8.31 Hz, H-3), 8.18- 8.27 (4H, m, H-4, 8, 2’, 6’)
13C NMR(400 MHz, CDCl3) δC 119.2 (C-3), 126.7 (C-6), 127.2 (C-4a), 127.5 (C-2’, 6’), 127.9 (C-5), 128.4 (C-3’, 5’), 128.7 (C-4’), 128.9 (C-7, 8), 129.8 (C-4), 130.3 (C-1’), 137.9 (C-8a), 157.2 (C-2)

Synthesis Reference(s)

Synthetic Communications, 23, p. 1959, 1993 DOI: 10.1080/00397919308009854
Chemical and Pharmaceutical Bulletin, 26, p. 3485, 1978 DOI: 10.1248/cpb.26.3485
Journal of the American Chemical Society, 71, p. 2327, 1949 DOI: 10.1021/ja01175a017

2-Phenylquinoline Preparation Products And Raw materials

Raw materials

PHENYLMAGNESIUM BROMIDE Quinoline Phenyllithium Bromobenzene 1,4-Dioxane

Preparation Products

2-Phenylquinoline Suppliers

Global( 199)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7786	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81148696 +8615536356810	1047@dideu.com	China	3459	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58

View Lastest Price from 2-Phenylquinoline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-01-06	2-Phenylquinoline 612-96-4	US $188.00-1.00 / KG	1KG	99%, 99.5% Sublimated	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2022-03-07	2-Phenylquinoline 612-96-4	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
2020-04-30	2-Phenylquinoline 612-96-4	US $0.10 / KG	1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd

2-Phenylquinoline
612-96-4
US $188.00-1.00 / KG
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

2-Phenylquinoline
612-96-4
US $1.10 / g
99.00%
Dideu Industries Group Limited

2-Phenylquinoline
612-96-4
US $0.10 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

2-Phenylquinoline Spectrum

2-Phenylquinoline(612-96-4)MS 2-Phenylquinoline(612-96-4)¹HNMR 2-Phenylquinoline(612-96-4)IR1 2-Phenylquinoline(612-96-4)IR2 2-Phenylquinoline(612-96-4)Raman

612-96-4(2-Phenylquinoline)Related Search:

Isoquinoline 8-Hydroxyquinoline Quinclorac 4-methylquinoline Ethoxyquin

1-Phenyl-2-nitropropene 6-Hydroxy-2(1H)-3,4-dihydroquinolinone quinolinium hydrogen sulphate Quinhydrone 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-MethylBr

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Pitavastatin calcium 2-Phenylquinolin-4-ol Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde

6,7-DIMETHOXY-1-(3,4,5-TRIETHOXYPHENYL)ISOQUINOLINE 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline Tariquidar

1of4

alpha-Phenylquinoline 2-Phenylquinoline, 99+% Phenylquinoline,99% a-Phenylquinoline 2-Phenylquinoline Phenylquinoline, 99% 2-Phenylquinoline 99% 2-Phenylquinoline, 99+% 1GR 2-Phenylquinoline> 830g Quinoline, 2-phenyl- 2-Phenylquinoline ISO 9001：2015 REACH 612-96-4 C6H5C9H6N C15H11N Building Blocks Quinolines Heterocyclic Building Blocks Heterocyclic Building Blocks Quinolines Building Blocks Quinolines, Quinazolines and derivatives API intermediates