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Agmatine sulfate

Agmatine sulfate
Agmatine sulfate structure
CAS No.
2482-00-0
Chemical Name:
Agmatine sulfate
Synonyms
ARGAMINE;gmatine sulfate;AGMATINE SULFATE;ARGAMINE SULFATE;AGARICUSBLAZTIP.E;AGMATINE SULPHATE;Agmatine sulfate,99%;Agmatine sulfate,70%;Agmatine sulfate,85+%;agmatine sulfate salt
CBNumber:
CB7421831
Molecular Formula:
C5H16N4O4S
Formula Weight:
228.27
MOL File:
2482-00-0.mol

Agmatine sulfate Properties

Melting point:
234-238 °C(lit.)
RTECS 
ME8413000
storage temp. 
−20°C
solubility 
H2O: 50 mg/mL
form 
powder
color 
white to off-white
Water Solubility 
Soluble in water, nearly insoluble in alcohol
Merck 
14,188
BRN 
3918807
InChIKey
PTAYFGHRDOMJGC-UHFFFAOYSA-N
CAS DataBase Reference
2482-00-0(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Safety Statements  22-24/25
WGK Germany  3
10
HS Code  29252900

Agmatine sulfate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A7127 Agmatine sulfate salt ≥97%, powder 2482-00-0 1g $66.8 2019-12-02 Buy
Sigma-Aldrich 101443 Agmatine sulfate salt Enzymatic decarboxylation product of arginine., 97% 2482-00-0 5g $231 2019-12-02 Buy
TCI Chemical A0310 Agmatine Sulfate >98.0%(T) 2482-00-0 1g $43 2019-12-02 Buy
TCI Chemical A0310 Agmatine Sulfate >98.0%(T) 2482-00-0 100mg $14 2019-12-02 Buy
Alfa Aesar H55363 Agmatine sulfate, 97% 2482-00-0 1g $45.8 2019-12-02 Buy

Agmatine sulfate Chemical Properties,Uses,Production

Description

Agmatine sulfate is the sulfate of the Agmatine. Agmatine is an aninoguanidine that is naturally derived from the arginine. It can exert modulatory effect on many molecular targets such as neurotransmitter systems, opioid analgesia, ion channels, and nitric oxide (NO) synthesis and polyamine metabolism. It has been also found that it can reverse the pain induced from inflammation, neuropathy, and spinal cord injury. Those effects make it a potential candidate for multiple pharmacological applications in the future. 

Chemical Properties

White to off-white powder

Uses

Agmatine Sulfate is a a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine a t α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects.

Biological Activity

Arginine metabolite that is synthesized within bovine brain and exhibits clonidine-displacing substance (CDS) activity. Putative endogenous ligand for the imidazoline binding site.

Purification Methods

Crystallise the salt from aqueous MeOH. The free base has m 101.5-103o, the gold chloride hydrochloride crystallises from H2O with m 223o(dec), and the picrate has m 236-238o. [Odo J Chem Soc Jpn 67 132 1946, Beilstein 4 I 420, 4 II 703, 4 III 575, 4 IV 1291.]

References

Fairbanks, C. A., et al. "Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury." Proceedings of the National Academy of Sciences of the United States of America97.19(2000):10584.
Kolesnikov, Yuri, S. Jain, and G. W. Pasternak. "Modulation of opioid analgesia by agmatine." European Journal of Pharmacology296.1(1996):17-22.
Su, R. B., J. Li, and B. Y. Qin. "A biphasic opioid function modulator: agmatine. "Acta Pharmacologica Sinica24.7(2003):631.
Galea, Elena, et al. "Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine." Biochemical Journal 316 ( Pt 1).1(1996):247.
https://en.wikipedia.org/wiki/Agmatine

Agmatine sulfate Preparation Products And Raw materials

Raw materials

Preparation Products


Agmatine sulfate Suppliers

Global( 235)Suppliers
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Taizhou Tianhong Biochemistry Technology Co., Ltd.
0523-86132544
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13156170209
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Capot Chemical Co.,Ltd.
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0371-55170693
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Zhejiang ZETian Fine Chemicals Co. LTD
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View Lastest Price from Agmatine sulfate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-30 Agmatine sulfate
2482-00-0
US $100.00 / KG 1KG 99% Customized career henan chemical co
2018-07-25 Agmatine sulfate
2482-00-0
US $10.00 / KG 1KG 99% 1000KG career henan chemical co

Agmatine sulfate Spectrum


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