VOACANGINE
- CAS No.
- 510-22-5
- Chemical Name:
- VOACANGINE
- Synonyms
- VOACANGINE;(-)-Voacangine;Carbomethoxyibogaine;12-Methoxyibogamine-18-carboxylic acid methyl ester;Ibogamine-18-carboxylic acid, 12-methoxy-, methyl ester
- CBNumber:
- CB7433742
- Molecular Formula:
- C22H28N2O3
- Molecular Weight:
- 368.47
- MDL Number:
- MFCD00077210
- MOL File:
- 510-22-5.mol
| Melting point | 223-224℃ (dec.) |
|---|---|
| Density | 1.25±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Store at -20°C,protect from light |
| solubility | DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml |
| form | A crystalline solid |
| FDA UNII | 9SY76D3YUK |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H332 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501 | |||||||||
| NFPA 704 |
|
VOACANGINE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 24692 | Voacangine ≥98% | 510-22-5 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 24692 | Voacangine ≥98% | 510-22-5 | 5mg | $356 | 2024-03-01 | Buy |
| Cayman Chemical | 24692 | Voacangine ≥98% | 510-22-5 | 10mg | $632 | 2024-03-01 | Buy |
| TRC | V757300 | (-)-Voacangine | 510-22-5 | 25mg | $695 | 2021-12-16 | Buy |
| TRC | V757300 | (-)-Voacangine | 510-22-5 | 50mg | $1200 | 2021-12-16 | Buy |
VOACANGINE Chemical Properties,Uses,Production
Description
This alkaloid is of widespread occurrence, being found in Stemmadenia species and also is Vocanga africana, v. dregii and V. obtusa. It forms colourless needles when crystallized from MeOH and has [0'10 - 42° (c 1.0, CHCI3). It sublimes under vacuum at 135°CjO.01 mm and is readily soluble in CHC13 or Me2CO, but only sparingly so in EtOH or MeOH. Hydrolysis with KOH followed by acidification with HCl yields Ibogaine (q.v.).
Uses
(-)-Voacangine is a bisindole alkaloid with ether-?a-?go-?go-?related gene channel blocker activity in vitro. hERG channel blocker.
Definition
ChEBI: (-)-voacangine is a monoterpenoid indole alkaloid with formula C22H28N2O3, isolated from several plant species. It has a role as an angiogenesis inhibitor, an antineoplastic agent and a plant metabolite. It is a monoterpenoid indole alkaloid, a tertiary amino compound, a methyl ester, an organic heteropentacyclic compound and an alkaloid ester. It is a conjugate base of a (-)-voacangine(1+).
References
lanot, Goutarel., Compt. rend., 241,986 (1955) Stauffacher, Seebeck., Helv. Chim. Acta, 41,169 (1958) Watts, Collera, Sandoval., Tetrahedron, 2, 173 (1958) Schuler, Verbeck, Warren.,J. Chern. Soc., 4776 (1958) Bartlett, Dickel, Taylor.,J. Amer. Chern. Soc., 80, 126 (1958) Renner, Prins, Stoll., Helv. Chim. Acta, 42,1572 (1959) Budzikiewicz etal., Bull. Soc. Chim. Fr., 1899 (1963)
VOACANGINE Preparation Products And Raw materials
Raw materials
Preparation Products
VOACANGINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8619133911216 | fanfan@kangcang.com.cn | China | 338 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2993 | 55 |
View Lastest Price from VOACANGINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | Voacangine
510-22-5
|
US $9.00-70.00 / g | 10g | 99% | 10 tons | Hebei Kangcang new material Technology Co., LTD | |
 |
2023-09-08 | Voacangine
510-22-5
|
US $50.00 / kg | 1kg | 0.99 | 10000 | Hebei Yanxi Chemical Co., Ltd. |
-
- Voacangine
510-22-5
- US $9.00-70.00 / g
- 99%
- Hebei Kangcang new material Technology Co., LTD
-
- Voacangine
510-22-5
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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