TYRPHOSTIN AG 1296
- CAS No.
- 146535-11-7
- Chemical Name:
- TYRPHOSTIN AG 1296
- Synonyms
- 1296;AG 1296;AG-1296;AG 1296;;TYRPHOSTIN AG 1296;TYRPHOSTIN AG 1296 USP/EP/BP;Tyrphostin AG 1296 (AG 1296);AG-1296 (Tyrphostin AG 1296);6,7-DIMETHOXY-3-PHENYLQUINOXALINE;6,7-DIMETHOXY-2-PHENYLQUINOXALINE;Quinoxaline,6,7-dimethoxy-2-phenyl-
- CBNumber:
- CB7435034
- Molecular Formula:
- C16H14N2O2
- Molecular Weight:
- 266.29
- MDL Number:
- MFCD00270913
- MOL File:
- 146535-11-7.mol
- MSDS File:
- SDS
| Boiling point | 420.2±40.0 °C(Predicted) |
|---|---|
| Density | 1.192±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in DMSO. |
| pka | 0.48±0.30(Predicted) |
| form | White solid |
| color | Yellow |
| Sensitive | Light Sensitive |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
TYRPHOSTIN AG 1296 price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J67039 | Tyrphostin AG-1296 98% | 146535-11-7 | 5mg | $182 | 2021-12-16 | Buy |
| Cayman Chemical | 10010592 | AG 1296 >98% | 146535-11-7 | 1mg | $28 | 2024-03-01 | Buy |
| Cayman Chemical | 10010592 | AG 1296 >98% | 146535-11-7 | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 10010592 | AG 1296 >98% | 146535-11-7 | 10mg | $207 | 2024-03-01 | Buy |
| Cayman Chemical | 10010592 | AG 1296 >98% | 146535-11-7 | 25mg | $448 | 2024-03-01 | Buy |
TYRPHOSTIN AG 1296 Chemical Properties,Uses,Production
Description
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-
Uses
Tyrphostin AG 1296, is the platelet-derived growth factor receptor (PDGFR) inhibitor, which can causes growth inhibition in glioblastoma cells.
Definition
ChEBI: 6,7-dimethoxy-2-phenylquinoxaline is a quinoxaline derivative.
target
PDGFR
References
1) Kovalenko et al. (1997), Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296; Biochemistry, 36 6260 2) Krystal et al. (1997), Induction of apoptosis and inhibition of small cell lung cancer growth by the quinoxaline tyrphostins; Cancer Res., 57 220 3) Strutz et al. (2001), TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2); Kidney Int., 59 579
TYRPHOSTIN AG 1296 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
View Lastest Price from TYRPHOSTIN AG 1296 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | TYRPHOSTIN AG 1296
146535-11-7
|
US $1.00 / g | 1g | 99% | 200kg | Career Henan Chemical Co |
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- TYRPHOSTIN AG 1296
146535-11-7
- US $1.00 / g
- 99%
- Career Henan Chemical Co