ChemicalBook >> CAS DataBase List >>4,4'-Biphenol

4,4'-Biphenol

4,4'-Biphenol structure

CAS No.: 92-88-6

Chemical Name:: 4,4'-Biphenol

Synonyms: PPDP;BIPHENOL;DOD;BIPHENOL S;P,P'-BIPHENOL;[1,1'-Biphenyl]-4,4'-diol;UBL5;(1R,2R)-Cyclohexane-1,2-diol;asmdod;Asm dod

CBNumber:: CB7448740

Molecular Formula:: C12H10O2

Molecular Weight:: 186.21

MDL Number:: MFCD00002348

MOL File:: 92-88-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:50

Product description	Number	Pack Size	Price
4,4′-Dihydroxybiphenyl 97%	168734	25g	$132
4,4′-Dihydroxybiphenyl 97%	168734	100g	$392
4,4'-Dihydroxybiphenyl >99.0%(GC)	B0464	25g	$60
4,4'-Dihydroxybiphenyl >99.0%(GC)	B0464	100g	$138
4,4'-Dihydroxybiphenyl >99.0%(GC)	B0464	500g	$375
More product size

Request For Quotation

4,4'-Biphenol Properties

Melting point	280-282 °C(lit.)
Boiling point	280.69°C (rough estimate)
Density	1.22
vapor pressure	0Pa at 25℃
refractive index	1.6010 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	9.74±0.26(Predicted)
form	Powder
color	Off-white to light beige or light gray
Water Solubility	sparingly soluble
BRN	1908886
Cosmetics Ingredients Functions	BLEACHING SKIN PROTECTING
InChI	1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H
InChIKey	VCCBEIPGXKNHFW-UHFFFAOYSA-N
SMILES	Oc1ccc(cc1)-c2ccc(O)cc2
LogP	2.7 at 20℃
CAS DataBase Reference	92-88-6(CAS DataBase Reference)
EWG's Food Scores	2
FDA UNII	R8994A0904
NIST Chemistry Reference	p,p'-Biphenol(92-88-6)
EPA Substance Registry System	4,4'-Biphenyldiol (92-88-6)
UNSPSC Code	41116107
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Warning

Hazard statements

H252-H317-H412

Precautionary statements

P235-P261-P272-P273-P280-P302+P352

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

21-36/37/38-37/38/68-36

Safety Statements

26-36-24/25-36/37

RIDADR

3077

WGK Germany

RTECS

DV4725000

TSCA

TSCA listed

HazardClass

PackingGroup

III

HS Code

29061900

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

Hazard Classifications

Aquatic Chronic 3
Self-heat. 2
Skin Sens. 1

Toxicity

LD50 orl-rat: 9850 mg/kg TXAPA9 28,313,74

NFPA 704

	1
2		0

4,4'-Biphenol price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	168734	4,4′-Dihydroxybiphenyl 97%	92-88-6	25g	$132	2026-04-30	Buy
Sigma-Aldrich	168734	4,4′-Dihydroxybiphenyl 97%	92-88-6	100g	$392	2026-04-30	Buy
TCI Chemical	B0464	4,4'-Dihydroxybiphenyl >99.0%(GC)	92-88-6	25g	$60	2026-04-30	Buy
TCI Chemical	B0464	4,4'-Dihydroxybiphenyl >99.0%(GC)	92-88-6	100g	$138	2026-04-30	Buy
TCI Chemical	B0464	4,4'-Dihydroxybiphenyl >99.0%(GC)	92-88-6	500g	$375	2026-04-30	Buy

Product number	Packaging	Price	Buy
168734	25g	$132	Buy
168734	100g	$392	Buy
B0464	25g	$60	Buy
B0464	100g	$138	Buy
B0464	500g	$375	Buy

4,4'-Biphenol Chemical Properties,Uses,Production

Chemical Properties

Powder

Uses

Biphenol is an intermediate used in the manufacture of thermoplastics such as liquid crystalline polymers (LCP), polyesters, polycarbonates and polysulfones.

Uses

4,4'-biphenol be used intermediate liquid crystal polymers raw materials. Synthetic polymers, due to its excellent heat resistance, it is used as polyester, urethane modified monomer, polycarbonate, polysulfone, and epoxy resin, for the manufacture of an excellent engineering plastics and composite materials. Antioxidant antioxidants for rubber and plastics. Dye intermediates or petroleum products stabilizer.

Uses

Intermediates of Liquid Crystals

Definition

ChEBI: A member of the class of hydroxybiphenyls that is biphenyl with hydroxy groups at positions 4 and 4'.

Production Methods

4,4'-Biphenol can be synthesized in excellent yields by debutylation of 3,3',5,5'-tetra-tert-butyl-4,4'-dihydroxybiphenyl. Other production processes are the alkaline fusion of 4,4'-biphenyldisulfonic acid, the boil down of benzidinebisdiazonium salts, and the decarboxylation of 4,4'-dihydroxybiphenyl-2-carboxylic acid. Symmetrically alkylated 4,4'-dihydroxybiphenyls such as 4,4'-dihydroxy-2,2',3,3',5,5',6,6'-hexamethylbiphenyl are preferably obtained by the oxidative coupling of the corresponding substituted monophenols. Here, diphenoquinones are generally formed in the first step which must be reduced. Phenol itself always gives isomeric mixtures of dihydroxybiphenyls on coupling with various oxidants. These mixtures are also formed by alkaline fusion of 4,4'-dihydroxybiphenylsulfone.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intraperitoneal route.Moderately toxic by skin contact. Mildly toxic byingestion. Human mutation data reported. When heated todecomposition it emits acrid smoke and irritating fumes.

Purification Methods

Recrystallise the biphenol from aqueous EtOH preferably under N2 to avoid oxidation to the extended qiunone. It is characterized as the dimethyl derivative (4,4’-dimethoxybiphenyl) from which it is prepared by demethylation. The dimethoxy derivative has m 176.5-177o (from AcOH, EtOH, hexane or *C6H6) and sublimes in vacuo. [Williamson & Rodebush J Am Chem Soc 63 3019 1941, Beilstein 6 I 485, 6 II 962, 6 III 6389, 6 IV 6651.]

Description

PPIase Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 163 amino acids & having a molecular mass of 18.2 kDa.
The PIN1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA, PLK I, Wee, and Myt1 kinases), several transcription factors like b-Catenin, c-Jun, and the tumor suppressor protein p53, and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1.

4,4'-Biphenol synthesis

Synthesis of 4,4'-Biphenol from 3,3',5,5'-TETRA(TERT-BUTYL)[1,1'-BIPHENYL]-4,4'-DIOL

4,4'-Biphenol Preparation Products And Raw materials

Raw materials

4,4'-Bis(trimethylsilyloxy)biphenyl 6,6'-DI-TERT.BUTYL-4,4'-BI-ORTHO-CRESOL 4-HYDROXY-4'-METHOXYBIPHENYL 4,4'-Dimethoxybiphenyl 3,3',5,5'-TETRA(TERT-BUTYL)[1,1'-BIPHENYL]-4,4'-DIOL

4-Hydroxy-4'-fluorobiphenyl 4,4'-Difluorobiphenyl 1-Chloro-4-fluorobenzene 4-Bromophenol

1of2

Preparation Products

4'-Hydroxy-4-biphenylcarbonitrile 6fapbp 3,3',5,5'-tetraformyl-4,4'-biphenyldiol 4,4'-BIPHENYLDICARBONITRILE Cyanic acid, [1,1'-biphenyl]-4,4'-diyl ester

[1,1'-biphenyl]-4,4'-diyl bis(2-Methylacrylate) 3,3',5,5'-tetrabromo-[1,1'-biphenyl]-4,4'-diol

1of2

4,4'-Biphenol Suppliers

Global( 563)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
HANGZHOU HAILAN CHEMICAL CO.,LTD.	+86-57156122185 +86-15967590394	sales@hailan-chem.com	China	398	58
Jiangxi Huihe Chemical Co., Ltd.	+86-19189228086 +8618858568638	wuzhouding@huihecrop.com	China	886	58
JiangXi Bobert Imp&Exp Co.,LTD	+8618071643627	rze2024@163.com	China	226	58
Nantong Root King lmport&Export Co.,Ltd	+86-13951333918 +86-15725632777	sales@ntrootking.com	China	190	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
Hebei Longbang Technology Co., LTD	+86-18633929156	admin@hblongbang.com	China	972	58
HebeiShuoshengImportandExportco.,Ltd	+86-18532138899	L18532138899@163.com	China	939	58

Supplier	Advantage
HANGZHOU HAILAN CHEMICAL CO.,LTD.	58
Jiangxi Huihe Chemical Co., Ltd.	58
JiangXi Bobert Imp&Exp Co.,LTD	58
Nantong Root King lmport&Export Co.,Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Hebei Longbang Technology Co., LTD	58
HebeiShuoshengImportandExportco.,Ltd	58

View Lastest Price from 4,4'-Biphenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	4,4'-Biphenol 92-88-6	US $0.00 / KG	25KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-30	4,4'-Biphenol 92-88-6	US $4.90-4.90 / kg	1kg	99	20ton	HANGZHOU HAILAN CHEMICAL CO.,LTD.
2026-03-20	4,4'-Biphenol 92-88-6	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

4,4'-Biphenol
92-88-6
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4,4'-Biphenol
92-88-6
US $4.90-4.90 / kg
99
HANGZHOU HAILAN CHEMICAL CO.,LTD.

4,4'-Biphenol
92-88-6
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4,4'-Biphenol Spectrum

4,4'-Biphenol(92-88-6)¹HNMR 4,4'-Biphenol(92-88-6)IR1 4,4'-Biphenol(92-88-6)IR2 4,4'-Biphenol(92-88-6)Raman

92-88-6(4,4'-Biphenol)Related Search:

4,4'-Diacetylbiphenyl 1,3-Dihydroxyacetone tert-Butylhydroquinone 4,4'-Ethylenedianiline Catechol

Triclosan Biphenyl-4,4'-dicarboxylic acid Resorcinol 2-Phenylphenol Biphenyl

4,4'-Dimethylbiphenyl 4-Phenylphenol Hydroquinone Benzidine 4-tert-Butylcatechol

1-Hydroxyethylidene-1,1-diphosphonic acid 6,6’-diamino-m’-bipheno 2,2'-Biphenol

1of4

(1,1’-Biphenyl)-4,4’-diol 1-(9,10-dihydroanthracen-1-yl)-9,10-dihydroanthracene Biphenyl-4,4'-diol 4,4'-Dihydroxybiphenyl 4,4'-Dihydroxydiphenyl 4,4'-Diphenol P,P'-DIPHENOL P,P'-DIHYDROXYBIPHENYL DOD)4,4'-Dihydroxy 4,4'-Dihydroxydiphenyl (DOD) 4,4- twohydroxydiphenyl 4,4'-Dihydroxybiphenyl 97% 4,4'-Dihydroxybiphenyl, 97+% NIMA-interacting protein 1 PIN1 human 4,4'-Dihydroxybiphenyl Vetec(TM) reagent grade, 97% 4,4′-Dihydroxybiphenyl, >=98% 4,4'-Dihydroxy-1,1'-biphenyl 4,4'-Dioxydiphenyl Antioxidant DOD antioxidantdod Asm dod asmdod para,para'-Biphenol p-Dihydroxydiphenyl Phenol p-(p-Hydroxyphenyl)- USAF do-30 usafdo-30 [1,1’-biphenyl]-4,4’-diol 4,4’-bisphenol 4,4'-DIPHENOL 4 4'-BIPHENOL SUBLIMED ZONE-REFINED & 4,4''-BIPHENOL, REFINED 99.5+% 4,4''-BIPHENOL, 99.94% JAPAN IMPORT 4,4μ-Biphenol, 4,4μ-Biphenyldiol, 4,4μ-Diphenol 4,4'-Biphenol,97% 4,4'-Dihydroxybiphenyl ,99% 4,4'-Diphenol PPDP 4,4'-Bipheno 4'-Biphenol 4,4'-Dihydroxybiphenyl, 99%, for synthesis 4,4'-Biphenol > 4,4'-Dihydroxybiphenyl@100 μg/mL in MeOH 4,4'-Biphenol,99% 4,4'-Biphenol ISO 9001：2015 REACH 4,4'-Biphenol 92-88-6 4-(4-hydroxyphenyl)phenol BIPHENOL S UBL5 (1R,2R)-Cyclohexane-1,2-diol -Dihydroxybiphenyl 4,4, BIPHENOLE Felbinac Impurity 41 4,4’- Dihydroxy Biphenyl (4-4’-Biphenol) 4,4'-Biphenol 4,4'-Dihydroxydiphenyl 1,1'-Biphenyl]-4,4'-diol 4,4’-DihydroxyBiphenyl(4-4’-Biphenol) 4,4'-Dihydroxybiphenyl C12635500 4.4’-Dihydroxybiphenyl Biphenyl-4,4'-diol