Pazinaclone
- CAS No.
- 103255-66-9
- Chemical Name:
- Pazinaclone
- Synonyms
- A77000;A-77000;DN-2327;A 77000;Paz·Naclone;Pazinaclone;2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-3h-isoindol-1-one;2-(7-Chloro-1,8-naphthyridine-2-yl)-3-[2-oxo-2-(1,4-dioxa-8-azaspiro[4.5]decane-8-yl)ethyl]isoindoline-1-one;8-[[2-(7-Chloro-1,8-naphthyridin-2-y1)-2，3-dihydro-3-oxo-1H-isoindol-1-y1]acetyl]-1，4-dioxa-8-azaspiro[4.5]decane;8-[[[2-(7-Chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1H-isoindol]-1-yl]acetyl]-1,4-dioxa-8-azaspiro[4.5]decane
- CBNumber:
- CB7453773
- Molecular Formula:
- C25H23ClN4O4
- Molecular Weight:
- 478.93
- MDL Number:
- MFCD00864702
- MOL File:
- 103255-66-9.mol
| Melting point | 238-239° |
|---|---|
| Boiling point | 712.5±60.0 °C(Predicted) |
| Density | 1.48±0.1 g/cm3(Predicted) |
| pka | 1.62±0.30(Predicted) |
| FDA UNII | MHK03047IJ |
Pazinaclone price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0003761 | PAZINACLONE 95.00% | 103255-66-9 | 100MG | $885.31 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003761 | PAZINACLONE 95.00% | 103255-66-9 | 1G | $2804.55 | 2021-12-16 | Buy |
| AHH | MT-57662 | Pazinaclone 98% | 103255-66-9 | 0.5g | $910 | 2021-12-16 | Buy |
| Chemenu | CM139296 | 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(2-oxo-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)ethyl)isoindolin-1-one 95% | 103255-66-9 | 1g | $1342 | 2021-12-16 | Buy |
| Crysdot | CD31004783 | Pazinaclone 95+% | 103255-66-9 | 1g | $1424 | 2021-12-16 | Buy |
Pazinaclone Chemical Properties,Uses,Production
Description
Pazinaclone is a nonbenzodiazepine partial agonist. Animal work has shown that it has anxiolytic and anticonvulsant activity. Pazinaclone does not, however, produce the sedative, muscle relaxant, or motor coordination effects seen with diazepam (Waka and Fukada 1991). Phase II clinical trials are currently under way in the United States, Europe, and Japan, which have so far demonstrated that it is well tolerated and seems to cause significantly less sedation than do benzodiazepines (Uchiumi et al. 1992).
Uses
Anti-anxiety agent.
Pharmacokinetics
Pazinaclone is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Other cyclopyrrolone drugs include zopiclone and eszopiclone. Pazinaclone has a very similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties, but with less amnestic effects, and at low doses it is a relatively selective anxiolytic, with sedative effects only appearing at higher doses. Pazinaclone produces its sedative and anxiolytic effects by acting as a partial agonist at GABAA benzodiazepine receptors, although pazinaclone is more subtype-selective than most benzodiazepines.
Pazinaclone Preparation Products And Raw materials
Raw materials
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Preparation Products
Pazinaclone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2127 | 70 |
View Lastest Price from Pazinaclone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-18 | Pazinaclone
103255-66-9
|
US $88.00 / KG | 1KG | 99% | 100000T | Xiamen Wonderful Bio Technology Co., Ltd. |
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- Pazinaclone
103255-66-9
- US $88.00 / KG
- 99%
- Xiamen Wonderful Bio Technology Co., Ltd.
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