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BKI-1369

BKI-1369 structure

CAS No.: 1951431-22-3

Chemical Name:: BKI-1369

Synonyms: BKI-1369;BKI1369,BKI 1369;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(2-ethoxy-6-quinolinyl)-1-[(1-methyl-4-piperidinyl)methyl]-

CBNumber:: CB74667646

Molecular Formula:: C23H27N7O

Molecular Weight:: 417.51

MDL Number:: MFCD32197194

MOL File:: 1951431-22-3.mol

Last updated:2023-05-21 10:59:17

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BKI-1369 Properties

Boiling point	626.8±50.0 °C(Predicted)
Density	1.38±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 50 mg/mL (119.76 mM)
pka	9.02±0.10(Predicted)

BKI-1369 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0082202	BKI-1369 99.71%	1951431-22-3	5mg	$500	2021-12-16	Buy
ChemScene	CS-0082202	BKI-1369 99.71%	1951431-22-3	10mg	$850	2021-12-16	Buy
ChemScene	CS-0082202	BKI-1369 99.71%	1951431-22-3	50mg	$2400	2021-12-16	Buy
ChemScene	CS-0082202	BKI-1369 99.71%	1951431-22-3	100mg	$3600	2021-12-16	Buy
DC Chemicals	DC22637	BKI1369 >98%	1951431-22-3	10mg	$500	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0082202	5mg	$500	Buy
CS-0082202	10mg	$850	Buy
CS-0082202	50mg	$2400	Buy
CS-0082202	100mg	$3600	Buy
DC22637	10mg	$500	Buy

BKI-1369 Chemical Properties,Uses,Production

Description

BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves[1]. IC50: 1.52 μM (hERG)[1]

References

[1]. Lee S, et al. Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis. Antimicrob Agents Chemother. 2018 Jun 26;62(7).

BKI-1369 Preparation Products And Raw materials

Raw materials

Preparation Products

BKI-1369 Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
cjbscvictory	13348960310 13348960310	3003867561@qq.com	China	10011	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9180	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
DC Chemicals	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
cjbscvictory	58
TargetMol Chemicals Inc.	58
RD International Technology Co., Limited	58

BKI-1369 BKI1369,BKI 1369 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(2-ethoxy-6-quinolinyl)-1-[(1-methyl-4-piperidinyl)methyl]- 1951431-22-3