Anti-Synaptophysin antibody, Mouse monoclonal

Uses

Anti-Synaptophysin antibody, Mouse monoclonal has been used in following immunochemical techniques:

• Immunoblotting
• Immunohistochemistry
• Immunofluorescence

General Description

Synaptophysin (SYP) is encoded by the gene mapped to human chromosome Xp11.23-p11.22. The encoded protein has a molecular mass of 38kDa and is exclusively localized to the membrane of presynaptic vesicles.

Biochem/physiol Actions

Synaptophysin (SYP) facilitates neurotransmitter release and synaptic plasticity. It is also implicated in synaptic vesicle formation and exocytosis. Mutation in the gene increases the risk of susceptibility to schizophrenia. It is widely used as a potential marker to study the circulation of synapses in the brain and to discover the basic features of the life cycle of synaptic vesicles (SVs).