ChemicalBook >> CAS DataBase List >>9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER

CAS No.
57790-53-1
Chemical Name:
9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER
Synonyms
PDKOSADNQUKMKP-QFPSZITRSA-N;PROSTAGLANDIN E2 P-BENZAMIDOPHENYL ESTER;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER;Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, 4-(benzoylamino)phenyl ester, (5Z,11α,13E,15S)-
CBNumber:
CB7470501
Molecular Formula:
C33H41NO6
Molecular Weight:
547.68
MDL Number:
MFCD02259328
MOL File:
57790-53-1.mol
Last updated:2023-06-08 09:03:09

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER Properties

solubility DMF: 65 mg/ml; DMSO: 28 mg/ml; Ethanol: 6 mg/ml; PBS pH 7.2: <125 μg/ml
form A crystalline solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H360
Precautionary statements  P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501
NFPA 704
0
2 0

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14054 Prostaglandin E2 p-benzamidophenyl ester ≥98% 57790-53-1 1mg $54 2024-03-01 Buy
Cayman Chemical 14054 Prostaglandin E2 p-benzamidophenyl ester ≥98% 57790-53-1 5mg $231 2024-03-01 Buy
Cayman Chemical 14054 Prostaglandin E2 p-benzamidophenyl ester ≥98% 57790-53-1 10mg $410 2024-03-01 Buy
AK Scientific 1579AH 9-oxo-11alpha,15S-Dihydroxy-prosta-5Z,13E-dien-1-oicacid,(4-benzoylamino)phenylester 57790-53-1 1mg $156 2021-12-16 Buy
Product number Packaging Price Buy
14054 1mg $54 Buy
14054 5mg $231 Buy
14054 10mg $410 Buy
1579AH 1mg $156 Buy

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER Chemical Properties,Uses,Production

Description

PGE2 p-benzamidophenyl ester is a crystalline derivative of PGE2. PGE2 is one of the primary COX products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.1,2,3,4 The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4.5 Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

Definition

ChEBI: Prostaglandin E2 p-benzamidophenyl ester is a prostanoid.

References

1. Willis, A.L., and Cornelsen, M. Repeated injection of prostaglandin E2 in rat paws induces chronic swelling and a marked decrease in pain threshold Prostaglandins 3(3),353-357(1973).
2. Jackson, G.M., Sharp, H.T., and Varner, M.W. Cervical ripening before induction of labor: A randomized trial of prostaglandin E2 gel versus low-dose oxytocin Am. J. Obstet. Gynecol. 171(4),1092-1096(1994).
3. Robert, A., Schultz, J.R., Nezamis, J.E., et al. Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16,16-dimethyl PGE2. Intravenous, oral and intrajejunal administration Gastroenterology 70(3),359-370(1976).
4. Arvind, P., Papavassiliou, E.D., Tsioulias, G.J., et al. Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines Biochemistry 34(16),5604-5609(1995).
5. Coleman, R.A., Smith, W.L., and Narumiya, S. International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes Pharmacol. Rev. 46(2),205-229(1994).

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
PROSTAGLANDIN E2 P-BENZAMIDOPHENYL ESTER 9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID, (4-BENZOYLAMINO) PHENYL ESTER PDKOSADNQUKMKP-QFPSZITRSA-N Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, 4-(benzoylamino)phenyl ester, (5Z,11α,13E,15S)- 57790-53-1 C33H41NO6