8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
- CAS No.
- 102146-07-6
- Chemical Name:
- 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
- Synonyms
- DPCPX;1,3-Dpcpx;PD 116,948;8-CYCLOPENTYL-1;PD-116948(DPCPX);DPCPX, PD 116,948;3-DIPROPYLXANTHINE;Levodropropizine Impurity 15;cyclopentyl-1,3-dipropylxanthine;1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE
- CBNumber:
- CB7472080
- Molecular Formula:
- C16H24N4O2
- Molecular Weight:
- 304.39
- MDL Number:
- MFCD00055117
- MOL File:
- 102146-07-6.mol
Melting point | 178°C |
---|---|
Boiling point | 535.1±42.0 °C(Predicted) |
Density | 1.195±0.06 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | DMSO: >10 mg/mL |
pka | 9.01±0.70(Predicted) |
form | solid |
color | white |
Stability | Store tightly sealed at RT; Solutions at 4 deg C for several days |
CAS DataBase Reference | 102146-07-6(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 9PTP4FOI9E |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
WGK Germany | 3 |
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C101 | 8-Cyclopentyl-1,3-dipropylxanthine solid | 102146-07-6 | 25mg | $91.6 | 2024-03-01 | Buy |
Sigma-Aldrich | C101 | 8-Cyclopentyl-1,3-dipropylxanthine solid | 102146-07-6 | 100mg | $200 | 2024-03-01 | Buy |
Tocris | 0439 | DPCPX ≥99%(HPLC) | 102146-07-6 | 100 | $195 | 2021-12-16 | Buy |
TRC | C988500 | 8-Cyclopentyl-1,3-dipropylxanthine | 102146-07-6 | 50mg | $80 | 2021-12-16 | Buy |
Usbiological | 255190 | DPCPX | 102146-07-6 | 100mg | $446 | 2021-12-16 | Buy |
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
8-Cyclopentyl-1,3-dipropylxanthine has been used as an adenosine receptor (A1AR) antagonist in macrophages and human umbilical vein endothelial cells (HUVECs). It has also been used as A1AR antagonist in MCF-7 breast cancer cell line to test its anti-cancer effect.
Uses
DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist
Definition
ChEBI: An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Biological Activity
Potent and selective A 1 adenosine receptor antagonist, both in vitro and in vivo . K i values are 3.9, 130, 50 and 4000 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively.
Biochem/physiol Actions
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is a selective A1?adenosine receptor antagonist. DPCPX possesses anti-cancer functionality. It induces apoptosis in breast cancer cells and favors mRNA expression of caspases.
storage
Room temperature
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Preparation Products And Raw materials
Raw materials
Preparation Products
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40067 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
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