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POMALIDOMIDE-C9-CO2H

POMALIDOMIDE-C9-CO2H Structure
POMALIDOMIDE-C9-CO2H structure
CAS No.
2243000-24-8
Chemical Name:
POMALIDOMIDE-C9-CO2H
Synonyms
Pomalidomide-C?-CO?H;Pomalidomide-C9-COOH;POMALIDOMIDE-C9-CO2H;Thalidomide-4-NH-C9-COOH;10-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino]decanoic Acid;Decanoic acid, 10-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-;10-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)decanoic acid, Crosslinker?E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB74740493
Molecular Formula:
C23H29N3O6
Molecular Weight:
443.49
MDL Number:
MFCD32173784
MOL File:
2243000-24-8.mol
MSDS File:
SDS
Last updated:2024-04-01 13:48:23
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POMALIDOMIDE-C9-CO2H Properties

Boiling point 714.1±55.0 °C(Predicted)
Density 1.326±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form powder or crystals
pka 4.78±0.10(Predicted)

POMALIDOMIDE-C9-CO2H price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Iris Biotech GmbH PTC1120 Pomalidomide-C9-COOH 2243000-24-8 50mg $432 2021-12-16 Buy
Product number Packaging Price Buy
PTC1120 50mg $432 Buy

POMALIDOMIDE-C9-CO2H Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-C9-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and an alkyl-chain crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

POMALIDOMIDE-C9-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

POMALIDOMIDE-C9-CO2H Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2893 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 6818 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9374 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4955 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1285 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
Daicel Chiral Technologies (China)CO.,LTD 65
Sigma-Aldrich 80
Shanghai Chaolan Chemical Technology Center 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58

View Lastest Price from POMALIDOMIDE-C9-CO2H manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-C9-COOH pictures 2024-04-02 Pomalidomide-C9-COOH
2243000-24-8
 US $0.00 / mg 100mg >99.00% 100mg Xian confluore Biological Technology Co., Ltd.

2243000-24-8(POMALIDOMIDE-C9-CO2H)Related Search:

E3 ligase Ligand-Linker Conjugates 49 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3
Pomalidomide-amido-C1-Br Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide Pomalidomide-C6-PEG3-butyl iodide
4-[(8-Aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Pomalidomide-C3-NH2 Pomalidomide-C6-NH2?hydrochloride
Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

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POMALIDOMIDE-C9-CO2H Pomalidomide-C9-COOH Decanoic acid, 10-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 10-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)decanoic acid, Crosslinker?E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader Thalidomide-4-NH-C9-COOH 10-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino]decanoic Acid Pomalidomide-C?-CO?H 2243000-24-8