InSolution BAY 11-7082 - Calbiochem
- CAS No.
- Chemical Name:
- InSolution BAY 11-7082 - Calbiochem
- Synonyms
- InSolution BAY 11-7082 - Calbiochem
- CBNumber:
- CB74817351
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
InSolution BAY 11-7082 - Calbiochem price More Price(1)
InSolution BAY 11-7082 - Calbiochem Chemical Properties,Uses,Production
General Description
Potential anti-inflammatory agent. Selectively and irreversibly inhibits the TNFα-inducible phosphorylation of IκB-α (IC50 = 10 μM) without affecting the constitutive IκB-α phosphorylation. Decreases nuclear translocation of NFκB and inhibits TNFα-induced surface expression of the endothelial-leukocyte cell adhesion molecules E-selectin, VCAM-1, and ICAM-1. E-selectin inhibition was shown to be irreversible (IC50 ~10 μM). Also reversibly increased the activity of p38 kinase and JNK-1 and stimulated tyrosine phosphorylation of a 130-140 kDa protein.
Biochem/physiol Actions
Cell permeable: yes
InSolution BAY 11-7082 - Calbiochem Preparation Products And Raw materials
Raw materials
Preparation Products
InSolution BAY 11-7082 - Calbiochem Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
InSolution BAY 11-7082 - Calbiochem