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ACEA

ACEA
ACEA structure
CAS No.
220556-69-4
Chemical Name:
ACEA
Synonyms
ACEA;2'-CHLORO-AEA;ACEA (ethanol solution);ARACHIDONYL-2-CHLOROETHYLAMIDE;ARACHIDONYL-2'-CHLOROETHYLAMIDE;ARACHIDONOYL 2'-CHLOROETHYLAMIDE;ARACHIDONYL-2'-CHLOROETHYLAMIDE HYDRATE;N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenaMide
CBNumber:
CB7484072
Molecular Formula:
C22H36ClNO
Formula Weight:
365.98
MOL File:
220556-69-4.mol

ACEA Properties

RTECS 
JX3840800
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
oil
color 
pale yellow
Sensitive 
Air Sensitive

SAFETY

WGK Germany  3

ACEA price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A9719 Arachidonyl-2′-chloroethylamide hydrate ≥97% (HPLC), oil 220556-69-4 25mg $309 2018-11-13 Buy
Alfa Aesar J67294 N-Arachidonyl-2-chloroethylamide, 98% 220556-69-4 10mg $110 2018-11-13 Buy
Cayman Chemical 91054 Arachidonoyl 2'-Chloroethylamide ≥95% 220556-69-4 5mg $28 2018-11-13 Buy
Cayman Chemical 91054 Arachidonoyl 2'-Chloroethylamide ≥95% 220556-69-4 10mg $53 2018-11-13 Buy
Cayman Chemical 91054 Arachidonoyl 2'-Chloroethylamide ≥95% 220556-69-4 25mg $126 2018-11-13 Buy

ACEA Chemical Properties,Uses,Production

Uses

A synthetic agonist of the cannabinoid receptor 1 (CB1R). ACEA is considered to be a selective cannabinoid agonist as it binds primarily to the CB1R and has low affinity to the cannabinoid receptor 2 (CB2R).

Biological Activity

Potent and highly selective CB 1 receptor agonist (K i = 1.4 nM). Displays > 1400-fold selectivity over CB 2 receptors. Active in vivo . Also available as part of the Cannabinoid CB 1 Receptor Tocriset™ .

Enzyme inhibitor

This synthetic CB1 receptor agonist and anandamide (N- arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69-4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki = 1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM). ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster ovary cells expressing the human CB1 receptor. It also increases the binding of [ 35 S]GTPgS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. ACEA produces hypothermia in mice, an effect that is inhibited by co-administration of the CB1 receptor antagonist SR141716A.

Enzyme inhibitor

This synthetic CB1 receptor agonist and anandamide (N- arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69-4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki = 1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM). ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster ovary cells expressing the human CB1 receptor. It also increases the binding of [ 35 S]GTPgS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. ACEA produces hypothermia in mice, an effect that is inhibited by co-administration of the CB1 receptor antagonist SR141716A.

ACEA Preparation Products And Raw materials

Raw materials

Preparation Products


ACEA Suppliers

Global( 22)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15881 69
Ascent Scientific 4401179829988
4402030 700 369 customerservice@ascentscientific.co.uk United Kingdom 279 60
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15426 60
EMMX Biotechnology LLC 888-539-0666
888-539-0666 info@emmx.com United States 8455 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885
021-65675885 info@efebio.com China 9933 58
Jinan Yaoyan Pharmaceutical Co., Ltd.
- jnyaoyan@163.com China 3075 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com
meitaochem@126.com China 19113 58
BOC Sciences 1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 10000 58
Carbosynth --
-- sales@carbosynth.com United Kingdom 6480 58

220556-69-4(ACEA)Related Search:


  • N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE
  • ARACHIDONYL-2'-CHLOROETHYLAMIDE
  • ARACHIDONYL-2-CHLOROETHYLAMIDE
  • ARACHIDONOYL 2'-CHLOROETHYLAMIDE
  • ACEA
  • 2'-CHLORO-AEA
  • ARACHIDONYL-2'-CHLOROETHYLAMIDE HYDRATE
  • ACEA (ethanol solution)
  • (5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenaMide
  • 220556-69-4
  • C22H36ClNO
  • Cannabinoid receptor
  • Cannabinoid
  • Agonist
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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