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CD437

CAS No.
125316-60-1
Chemical Name:
CD437
Synonyms
CS-2691;ADAP-IME;Ro472077;Ro 472077;Ro-472077;CD 437/AHPN;AHPN;CD 437;CD-437;CD437;CD-437;CD 437;Adapalene IMpurity F;O-DesMethyl Adapalene
CBNumber:
CB7503287
Molecular Formula:
C27H26O3
Molecular Weight:
398.49
MDL Number:
MFCD03106506
MOL File:
125316-60-1.mol
MSDS File:
SDS
Last updated:2023-09-04 15:50:00

CD437 Properties

Melting point 271.6-276 °C
Boiling point 595.0±50.0 °C(Predicted)
Density 1.290
storage temp. -20°C
solubility DMSO: 26 mg/mL
form solid
pka 4.17±0.30(Predicted)
color yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
Safety Statements  22-24/25
WGK Germany  3
RTECS  QJ1975900

CD437 price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C5865 CD437 ≥98% (HPLC), solid 125316-60-1 5mg $258 2024-03-01 Buy
Sigma-Aldrich 178496 Apoptosis Activator VI, CD437/AHPN 125316-60-1 5mg $208 2024-03-01 Buy
Cayman Chemical 71610 CD437 ≥95% 125316-60-1 5mg $86 2024-03-01 Buy
Cayman Chemical 71610 CD437 ≥95% 125316-60-1 10mg $116 2024-03-01 Buy
Sigma-Aldrich C5865 CD437 ≥98% (HPLC), solid 125316-60-1 25mg $870 2024-03-01 Buy
Product number Packaging Price Buy
C5865 5mg $258 Buy
178496 5mg $208 Buy
71610 5mg $86 Buy
71610 10mg $116 Buy
C5865 25mg $870 Buy

CD437 Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An intermediate in the preparation of Adapalene derivatives.

Definition

ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.

Biological Activity

Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.

Biochem/physiol Actions

CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.

storage

Store at -20°C

CD437 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 109)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58

View Lastest Price from CD437 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CD 437 pictures 2020-01-13 CD 437
125316-60-1
US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co
  • CD 437 pictures
  • CD 437
    125316-60-1
  • US $1.00 / g
  • 95-99%
  • Career Henan Chemical Co

CD437 Spectrum

2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen 6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid O-DesMethyl Adapalene CD 437/AHPN Adapalene IMpurity F Apoptosis Activator VI, CD437/AHPN ADAP-IME 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid CD437;CD-437;CD 437 CS-2691 O-Desmethyl Adapalene-13C6 Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem AHPN;CD 437;CD-437 Apoptosis Activator VI 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthoic Acid 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)- 6-(3-(Adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoic acid inhibit,Retinoid X receptors,CD437,CD-437,CD 437,RAR/RXR,Inhibitor,Autophagy,Retinoic acid receptors CD437/6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid Ro 472077 Ro472077 Ro-472077 125316-60-1 Aromatics Intermediates & Fine Chemicals Pharmaceuticals