(S)-Tert-butyl (piperidin-3-ylmethyl)carbamate
- CAS No.
- 1016167-99-9
- Chemical Name:
- (S)-Tert-butyl (piperidin-3-ylmethyl)carbamate
- Synonyms
- (S)-N-Boc-1-(3-piperidyl)methanamine;(R)-3-(Boc-aminomethyl)piperidine,97%;tert-butyl (S)-(piperidin-3-ylmethyl)carbamate;S-3-N-Boc-Aminomethyl Piperidine Hydrochloride;tert-Butyl N-[(3S)-3-Piperidinylmethyl]carbamate;tert-Butyl-N-[(3S)-piperidine-3ylmethyl)] carbamate;Carbamic acid, N-[(3S)-3-piperidinylmethyl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB75832009
- Molecular Formula:
- C11H22N2O2
- Molecular Weight:
- 214.3
- MDL Number:
- MFCD03093385
- MOL File:
- 1016167-99-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl N-[(3S)-piperidin-3-ylmethyl]carbamate 97.0% | 4H56-1-S03 | 250mg | $190 |
| (S)-tert-butyl(piperidin-3-ylmethyl)carbamate | 0420AA | 5g | $242 |
| (S)-tert-butyl(piperidin-3-ylmethyl)carbamate | CS-W006519 | 5g | $255 |
| (S)-3-(Boc-aminomethyl)piperidine 97+% ee | AS55017-3S | 5G | $260 |
| (S)-3-(Boc-aminomethyl)-piperidine | 112215 | 1g | $284 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
(S)-Tert-butyl (piperidin-3-ylmethyl)carbamate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| SynQuest Laboratories | 4H56-1-S03 | tert-Butyl N-[(3S)-piperidin-3-ylmethyl]carbamate 97.0% | 1016167-99-9 | 250mg | $190 | 2021-12-16 | Buy |
| AK Scientific | 0420AA | (S)-tert-butyl(piperidin-3-ylmethyl)carbamate | 1016167-99-9 | 5g | $242 | 2021-12-16 | Buy |
| ChemScene | CS-W006519 | (S)-tert-butyl(piperidin-3-ylmethyl)carbamate | 1016167-99-9 | 5g | $255 | 2021-12-16 | Buy |
| Activate Scientific | AS55017-3S | (S)-3-(Boc-aminomethyl)piperidine 97+% ee | 1016167-99-9 | 5G | $260 | 2021-12-16 | Buy |
| Matrix Scientific | 112215 | (S)-3-(Boc-aminomethyl)-piperidine | 1016167-99-9 | 1g | $284 | 2021-12-16 | Buy |
(S)-Tert-butyl (piperidin-3-ylmethyl)carbamate Chemical Properties,Uses,Production
Synthesis
142643-29-6
1016167-99-9
The general procedure for the synthesis of tert-butyl (S)-(piperidin-3-ylmethyl)carbamate from 3-Boc-aminomethylpiperidine is as follows:Example 4 Synthesis of (3S)-N-(tert-butoxycarbonyl)-3-aminomethylpiperidine (Compound 5): N-(tert-butoxycarbonyl)-3-aminomethylpiperidine (10 g, 47 mmol, 1 equiv), (-)-O,O' -di-β-tosyl-L-tartaric acid (15.52 g, 47 mmol, 1 eq.) were mixed with dry methanol (100 ml) and slowly heated to reflux to form a homogeneous solution. The reaction mixture was cooled to room temperature and stirred for 5-6 hours. The resulting white solid was filtered and washed with a minimal amount of anhydrous methanol. The crude product was purified by recrystallization from methanol. The resulting compound was suspended in distilled water (25 ml) and cooled to 0°C. 10% sodium carbonate solution (100 ml) was added in batches until the reaction mixture was basic and stirring was continued for 10 minutes. The reaction mixture was extracted with ethyl acetate (5 x 50 ml), the organic layer was separated and concentrated under reduced pressure after drying to give the target compound 3. Yield: 3.28 g (65%). [α]D: +11.03 (c=0.10, methanol). Melting point: 64-66°C. IR (pure): 3360, 2972, 1703, 1519, 1455, 1365, 1255, 1172 cm-1. 1H NMR (CDCl3, 300MHz) δ: 1.01-1.21 (m, 2H, H-4); 1.39 (s, 9H, -OC(CH3)3); 1.57- 1.72 (m, 3H, H-3, H-5); 2.20-2.31 (m, 1H, CHaNHBoc); 2.49-2.56 (m, 1H, CHbNHBoc); 2.90-3.03 (m, 4H, H-2, H-4); 4.77 (brs, 1H, NH).13C NMR (CDCl3, 300MHz) δ : 26.56, 29.03, 29.58, 38.44, 44.99, 47.46, 51.16, 79.73, 156.72. FAB MS (m/z): 215 (M+1, 114).
References
[1] Patent: WO2012/104866, 2012, A1. Location in patent: Page/Page column 17-18
(S)-Tert-butyl (piperidin-3-ylmethyl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-Tert-butyl (piperidin-3-ylmethyl)carbamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49968 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
View Lastest Price from (S)-Tert-butyl (piperidin-3-ylmethyl)carbamate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | S-3-N-BOC-AMINOMETHYL PIPERIDINE-HCl
1016167-99-9
|
US $2.00 / KG | 1g | 98%MIN | ASK | Career Henan Chemical Co |
-
- S-3-N-BOC-AMINOMETHYL PIPERIDINE-HCl
1016167-99-9
- US $2.00 / KG
- 98%MIN
- Career Henan Chemical Co
